Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Brandi N Williamson"'
Autor:
Meaghan Flagg, Kerry Goldin, Lizzette Pérez-Pérez, Manmeet Singh, Brandi N. Williamson, Nathanael Pruett, Chuong D. Hoang, Emmie de Wit
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
There is tremendous heterogeneity in the severity of COVID-19 disease in the human population, and the mechanisms governing the development of severe disease remain incompletely understood. The emergence of SARS-CoV-2 variants of concern (VOC) Delta
Externí odkaz:
https://doaj.org/article/ec540c177e954033983095d97fb37a3b
Autor:
Emmie de Wit, Friederike Feldmann, Jacqueline Cronin, Kerry Goldin, Reinaldo Mercado-Hernandez, Brandi N. Williamson, Kimberly Meade-White, Atsushi Okumura, Julie Callison, Sarah Weatherman, Rebecca Rosenke, Victoria A. Avanzato, Jamie Lovaglio, Dana P. Scott, Andrea Marzi, Heinz Feldmann
Publikováno v:
EBioMedicine, Vol 87, Iss , Pp 104405- (2023)
Summary: Background: Nipah virus (NiV) causes recurrent outbreaks of lethal respiratory and neurological disease in Southeast Asia. The World Health Organization considers the development of an effective vaccine against NiV a priority. Methods: We pr
Externí odkaz:
https://doaj.org/article/dfff7aaf39d542d6855906a23c3664cd
Therapeutic Efficacy of Human Monoclonal Antibodies against Andes Virus Infection in Syrian Hamsters
Autor:
Brandi N. Williamson, Joseph Prescott, Jose L. Garrido, Raymond A. Alvarez, Heinz Feldmann, Maria I. Barría
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 10, Pp 2707-2710 (2021)
Andes virus, an orthohantavirus endemic to South America, causes severe hantavirus cardiopulmonary syndrome associated with human-to-human transmission. No approved treatments or vaccines against this virus are available. We show that a combined trea
Externí odkaz:
https://doaj.org/article/1f5f799122d1481f90e267d97e87fac0
Autor:
Robert J. Fischer, Neeltje van Doremalen, Danielle R. Adney, Claude Kwe Yinda, Julia R. Port, Myndi G. Holbrook, Jonathan E. Schulz, Brandi N. Williamson, Tina Thomas, Kent Barbian, Sarah L. Anzick, Stacy Ricklefs, Brian J. Smith, Dan Long, Craig Martens, Greg Saturday, Emmie de Wit, Sarah C. Gilbert, Teresa Lambe, Vincent J. Munster
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Emerging SARS-CoV-2 variants raise concerns about vaccine effectiveness. Here, the authors show that the ChAdOx1 nCoV-19 (AZD1222) vaccine protects Syrian hamsters from pulmonary infection and disease after infection with SARS-CoV-2 B.1.351 or B.1.1.
Externí odkaz:
https://doaj.org/article/cd521c32186f4059b6298768dcc0d51a
Autor:
Robert J. Fischer, Dylan H. Morris, Neeltje van Doremalen, Shanda Sarchette, M. Jeremiah Matson, Trenton Bushmaker, Claude Kwe Yinda, Stephanie N. Seifert, Amandine Gamble, Brandi N. Williamson, Seth D. Judson, Emmie de Wit, James O. Lloyd-Smith, Vincent J. Munster
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 9, Pp 2253-2255 (2020)
The coronavirus pandemic has created worldwide shortages of N95 respirators. We analyzed 4 decontamination methods for effectiveness in deactivating severe acute respiratory syndrome coronavirus 2 virus and effect on respirator function. Our results
Externí odkaz:
https://doaj.org/article/0f3a76f2a68942b09df6897d345cbc9c
Autor:
Kyle Rosenke, Michael A. Jarvis, Friederike Feldmann, Benjamin Schwarz, Atsushi Okumura, Jamie Lovaglio, Greg Saturday, Patrick W. Hanley, Kimberly Meade-White, Brandi N. Williamson, Frederick Hansen, Lizette Perez-Perez, Shanna Leventhal, Tsing-Lee Tang-Huau, Julie Callison, Elaine Haddock, Kaitlin A. Stromberg, Dana Scott, Graham Sewell, Catharine M. Bosio, David Hawman, Emmie de Wit, Heinz Feldmann
Publikováno v:
JCI Insight, Vol 5, Iss 23 (2020)
We remain largely without effective prophylactic/therapeutic interventions for COVID-19. Although many human COVID-19 clinical trials are ongoing, there remains a deficiency of supportive preclinical drug efficacy studies to help guide decisions. Her
Externí odkaz:
https://doaj.org/article/28b738a56bae42afa6e041613cef0ac9
Autor:
Ted Hackstadt, Abhilash I. Chiramel, Forrest H. Hoyt, Brandi N. Williamson, Cheryl A. Dooley, Paul A. Beare, Emmie de Wit, Sonja M. Best, Elizabeth R. Fischer
Publikováno v:
Viruses, Vol 13, Iss 9, p 1798 (2021)
A variety of immunolabeling procedures for both light and electron microscopy were used to examine the cellular origins of the host membranes supporting the SARS-CoV-2 replication complex. The endoplasmic reticulum has long been implicated as a sourc
Externí odkaz:
https://doaj.org/article/da0bb646eddd4b82911ad4eb61c121bb
Autor:
Brandi N. Williamson, Kimberly Meade-White, Kristin Boardman, Jonathan E. Schulz, Carson T. Telford, Dania M. Figueroa Acosta, Trenton Bushmaker, Robert J. Fischer, Kyle Rosenke, Heinz Feldmann
Publikováno v:
Viruses, Vol 13, Iss 6, p 1006 (2021)
Hantavirus pulmonary syndrome (HPS) is an often-fatal disease caused by New World hantaviruses, such as Sin Nombre orthohantavirus (SNV). In the US, >800 cases of HPS have been confirmed since it was first discovered in 1993, of which 43 were reporte
Externí odkaz:
https://doaj.org/article/70b3b53117504dde8e89badcbc82b78b
Autor:
Keesha Matz, Jackson Emanuel, Julie Callison, Don Gardner, Rebecca Rosenke, Reinaldo Mercado-Hernandez, Brandi N. Williamson, Heinz Feldmann, Andrea Marzi
Publikováno v:
Microorganisms, Vol 9, Iss 6, p 1178 (2021)
Zika virus (ZIKV), a member of the Flaviviridae family, is an important human pathogen that has caused epidemics in Africa, Southeast Asia, and the Americas. No licensed treatments for ZIKV disease are currently available. Favipiravir (T-705; 6-fluor
Externí odkaz:
https://doaj.org/article/392f68027eca4e5fa5d1e080bac02e8f
Therapeutic Efficacy of Human Monoclonal Antibodies against Andes Virus Infection in Syrian Hamsters
Autor:
Jose Luis Garrido, Brandi N. Williamson, Raymond A. Alvarez, Joseph Prescott, Heinz Feldmann, María Inés Barría
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 10, Pp 2707-2710 (2021)
Emerging Infectious Diseases
Emerging Infectious Diseases
Andes virus, an orthohantavirus endemic to South America, causes severe hantavirus cardiopulmonary syndrome associated with human-to-human transmission. No approved treatments or vaccines against this virus are available. We show that a combined trea