Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Brandee Decker-Rockefeller"'
Publikováno v:
Animal Models and Experimental Medicine, Vol 6, Iss 4, Pp 362-368 (2023)
Abstract Background Genetic analysis in human patients has linked mutations in PIK3CA, the catalytic subunit of PI‐3′Kinase, to sporadic incidences of vascular malformations. Methods We have developed a mouse model with inducible and endothelial
Externí odkaz:
https://doaj.org/article/7945351559c84f52a9fbd7bd6995bf7a
Publikováno v:
Cell Reports, Vol 24, Iss 11, Pp 2869-2882 (2018)
Summary: Cerebrovascular malformations (CVMs) affect approximately 3% of the population, risking hemorrhagic stroke, seizures, and neurological deficits. Recently Ras mutations have been identified in a majority of brain arterio-venous malformations.
Externí odkaz:
https://doaj.org/article/c0bba12a08d944f1a10fe59ad70e2bed