Zobrazeno 1 - 10
of 283
pro vyhledávání: '"Bram Verstockt"'
Autor:
Elise Schoefs, Séverine Vermeire, Marc Ferrante, João Sabino, Bram Verstockt, Luisa Avedano, Maria Stella De Rocchis, Magdalena Sajak-Szczerba, Roberto Saldaña, Noortje Straetemans, Martina Vandebroek, Rosanne Janssens, Isabelle Huys
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundAs the therapeutic landscape for inflammatory bowel disease (IBD) continues to expand, a need exists to understand how patients perceive and value different attributes associated with their disease as well as with current and emerging treat
Externí odkaz:
https://doaj.org/article/2f8326c20364467189da2d150be0f85c
Autor:
Aditi Kumar, Nuha Yassin, Alexandra Marley, Vittoria Bellato, Caterina Foppa, Gianluca Pellino, Pär Myrelid, Monica Millan, Beatriz Gros, Nicolas Avellaneda, Ignacio Catalan-Serra, Alaa El-Hussuna, João A. Cunha Neves, Joana Roseira, Miguel F. Cunha, Bram Verstockt, Dominik Bettenworth, Diane Mege, Matthew J. Brookes
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 16 (2023)
An estimated 2.5–3 million individuals (0.4%) in Europe are affected by inflammatory bowel disease (IBD). Whilst incidence rates for IBD are stabilising across Europe, the prevalence is rising and subsequently resulting in a significant cost to the
Externí odkaz:
https://doaj.org/article/a15373f99e224796af36e34233c99fe1
Autor:
Mallory Chavannes, Bram Verstockt, Mariangela Allocca, David T Rubin, Kerri Novak, Lynn Kysh, Noa Krugliak Cleveland, Michael Todd Dolinger, Tom S Robbins, Shintaro Sagami
Publikováno v:
BMJ Open Gastroenterology, Vol 10, Iss 1 (2023)
Introduction Inflammatory bowel diseases (IBD) are immune-mediated conditions that are increasing in incidence and prevalence worldwide. Their assessment and monitoring are becoming increasingly important, though complex. The best disease control is
Externí odkaz:
https://doaj.org/article/d5f309c116974899a71a02a8fc016e36
Autor:
Pieter Sinonquel, Peter Bossuyt, João Pedro Guedelha Sabino, Bram Verstockt, Takao Makino, Severine Vermeire, Raf Bisschops
Publikováno v:
Endoscopy International Open, Vol 11, Iss 09, Pp E880-E884 (2023)
Externí odkaz:
https://doaj.org/article/f74c0da4fc814777b8eb0604ed086d7c
Autor:
Nathalie Van den Berghe, Dahham Alsoud, Bram Verstockt, Séverine Vermeire, Paul Declerck, Debby Thomas
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 16 (2023)
Background: Since not all Crohn’s disease (CD) patients respond adequately to ustekinumab therapy, biomarkers could aid to monitor treatment response and optimize therapeutic outcomes. Objectives: To explore the dynamics of serum biomarker concentr
Externí odkaz:
https://doaj.org/article/e817b3d18ecf47298e4812bd3cb98c06
Autor:
Séverine Vermeire, Marc Ferrante, Padhmanand Sudhakar, Bram Verstockt, Jonathan Cremer, João Sabino, Sare Verstockt
Publikováno v:
BMJ Open Gastroenterology, Vol 10, Iss 1 (2023)
Objective To infer potential mechanisms driving disease subtypes among patients with inflammatory bowel disease (IBD), we profiled the transcriptome of purified circulating monocytes and CD4 T-cells.Design RNA extracted from purified monocytes and CD
Externí odkaz:
https://doaj.org/article/2411cee628884def842b2992831515db
Autor:
Huiwen Che, Tatjana Jatsenko, Lore Lannoo, Kate Stanley, Luc Dehaspe, Leen Vancoillie, Nathalie Brison, Ilse Parijs, Kris Van Den Bogaert, Koenraad Devriendt, Sabien Severi, Ellen De Langhe, Severine Vermeire, Bram Verstockt, Kristel Van Calsteren, Joris Robert Vermeesch
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract The early detection of tissue and organ damage associated with autoimmune diseases (AID) has been identified as key to improve long-term survival, but non-invasive biomarkers are lacking. Elevated cell-free DNA (cfDNA) levels have been obser
Externí odkaz:
https://doaj.org/article/3703af8193fe44ddb75b69cde0f61608
Autor:
Martina Poletti, Agatha Treveil, Luca Csabai, Leila Gul, Dezso Modos, Matthew Madgwick, Marton Olbei, Balazs Bohar, Alberto Valdeolivas, Denes Turei, Bram Verstockt, Sergio Triana, Theodore Alexandrov, Julio Saez-Rodriguez, Megan L. Stanifer, Steeve Boulant, Tamas Korcsmaros
Publikováno v:
npj Systems Biology and Applications, Vol 8, Iss 1, Pp 1-19 (2022)
Abstract Increasing evidence points towards the key role of the epithelium in the systemic and over-activated immune response to viral infection, including SARS-CoV-2 infection. Yet, how viral infection alters epithelial–immune cell interactions re
Externí odkaz:
https://doaj.org/article/738ae418fdc748b4b520a8a08ccc3aac
Autor:
Johanne Brooks-Warburton, Dezso Modos, Padhmanand Sudhakar, Matthew Madgwick, John P. Thomas, Balazs Bohar, David Fazekas, Azedine Zoufir, Orsolya Kapuy, Mate Szalay-Beko, Bram Verstockt, Lindsay J. Hall, Alastair Watson, Mark Tremelling, Miles Parkes, Severine Vermeire, Andreas Bender, Simon R. Carding, Tamas Korcsmaros
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Single Nucleotide Polymorphisms (SNPs) affect cellular regulatory networks, and SNP co-occurrences contribute to disease pathogenesis in ulcerative colitis (UC). Here the authors introduce iSNP, a precision medicine pipeline that combines genomics an
Externí odkaz:
https://doaj.org/article/8e6aeec152bd4dd190ead523041dd479
Autor:
Kaline Arnauts, Padhmanand Sudhakar, Sare Verstockt, Cynthia Lapierre, Selina Potche, Clara Caenepeel, Bram Verstockt, Jeroen Raes, Séverine Vermeire, João Sabino, Catherine Verfaillie, Marc Ferrante
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Microbial dysbiosis is an established finding in patients with inflammatory bowel disease (IBD), but host-microbial interactions are poorly understood. We aimed to unravel the effect of microbiota exposure on intestinal epithelial cells. Confluent Tr
Externí odkaz:
https://doaj.org/article/9f2e0aa4b7f14da68d410886ab58b74b