Výsledky vyhledávání - "Bram M. ter Ellen"

Akademický článek

Characterization of soluble TLR2 and CD14 levels during acute dengue virus infection

Autor: Vinit Upasani, Bram M. ter Ellen, Sotheary Sann, Sokchea Lay, Sothy Heng, Denis Laurent, Sowath Ly, Veasna Duong, Philippe Dussart, Jolanda M. Smit, Tineke Cantaert, Izabela A. Rodenhuis-Zybert

Publikováno v: Heliyon, Vol 9, Iss 6, Pp e17265- (2023)

Dengue virus infection results in a broad spectrum of diseases ranging from mild dengue fever (DF) to severe dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Hitherto, there is no consensus biomarker for the prediction of severe dengue

Externí odkaz: https://doaj.org/article/6571c78510974df5859a2edda28959b5

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Akademický článek

Mediators of Obesity Do Not Influence SARS-CoV-2 Infection or Activation of Primary Human Lung Microvascular Endothelial Cells In Vitro

Autor: Bram M. ter Ellen, Jelmer Niewold, Antine Flikweert, Anneke C. Muller Kobold, Peter Heeringa, Matijs van Meurs, Jolanda M. Smit, Peter H. J. van der Voort, Izabela A. Rodenhuis-Zybert, Jill Moser

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Clinical observations have shown that obesity is associated with the severe outcome of SARS-CoV-2 infection hallmarked by microvascular dysfunction in the lungs and other organs. Excess visceral fat and high systemic levels of adipose tissue (AT) der

Externí odkaz: https://doaj.org/article/1a9f1015c76f42d3b6ab2997db4c4c0a

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Akademický článek

TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis

Autor: José A. Aguilar-Briseño, Vinit Upasani, Bram M. ter Ellen, Jill Moser, Mindaugas Pauzuolis, Mariana Ruiz-Silva, Sothy Heng, Denis Laurent, Rithy Choeung, Philippe Dussart, Tineke Cantaert, Jolanda M. Smit, Izabela A. Rodenhuis-Zybert

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)

The mechanisms underlying immunpathologies in dengue virus (DENV) infection are incompletely understood. Here, authors show that TLR2 recognizes DENV particles inducing cytokine expression and activating vascular endothelium cells in vitro, and that

Externí odkaz: https://doaj.org/article/85dea333a8ac4394b33be3faacbbdbda

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Akademický článek

Resveratrol and Pterostilbene Inhibit SARS-CoV-2 Replication in Air–Liquid Interface Cultured Human Primary Bronchial Epithelial Cells

Autor: Bram M. ter Ellen, Nilima Dinesh Kumar, Ellen M. Bouma, Berit Troost, Denise P.I. van de Pol, Heidi H. van der Ende-Metselaar, Leonie Apperloo, Djoke van Gosliga, Maarten van den Berge, Martijn C. Nawijn, Peter H.J. van der Voort, Jill Moser, Izabela A. Rodenhuis-Zybert, Jolanda M. Smit

Publikováno v: Viruses, Vol 13, Iss 7, p 1335 (2021)

The current COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has an enormous impact on human health and economy. In search for therapeutic options, researchers have proposed resveratrol, a food supplemen

Externí odkaz: https://doaj.org/article/16c9bf2d5c77475aa3281a9cc2e0e074

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Akademický článek

TLR2 axis on peripheral blood mononuclear cells regulates inflammatory responses to non-infectious immature dengue virus particles.

Autor: José Alberto Aguilar Briseño, Lennon Ramos Pereira, Marleen van der Laan, Mindaugas Pauzuolis, Bram M Ter Ellen, Vinit Upasani, Jill Moser, Luís Carlos de Souza Ferreira, Jolanda M Smit, Izabela A Rodenhuis-Zybert

Publikováno v: PLoS Pathogens, Vol 18, Iss 10, p e1010499 (2022)

Severe dengue virus (DENV) infection is characterized by exacerbated inflammatory responses that lead to endothelial dysfunction and plasma leakage. We have recently demonstrated that Toll-like receptor 2 (TLR2) on blood monocytes senses DENV infecti

Externí odkaz: https://doaj.org/article/8ed23dd06b8b42bbac9a4af850b0e6eb

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TLR2 axis on peripheral blood mononuclear cells regulates inflammatory responses to circulating, non-infectious immature dengue virus particles

Autor: José A. Aguilar-Briseño, Lennon Ramos Pereira, Marleen van der Laan, Mindaugas Pauzuolis, Bram M. ter Ellen, Vinit Upasani, Jill Moser, Luís Carlos de Souza Ferreira, Jolanda M. Smit, Izabela A. Rodenhuis-Zybert

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9806ea4744f178991d5403bd51734995
https://doi.org/10.1101/2022.04.07.487433

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Characterization of Soluble TLR2 and CD14 Levels During Acute Dengue Virus Infection

Autor: Vinit Upasani, Bram M. ter Ellen, Sotheary Sann, Sokchea Lay, Heng Sothy, Denis Laurent, Sowath Ly, Veasna Duong, Philippe Dussart, Jolanda Smit, Tineke Cantaert, Izabela A. Rodenhuis-Zybert

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::538b677cb87768d53cff9677c3a34286
https://doi.org/10.2139/ssrn.4245553

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MOXIDECTIN AND IVERMECTIN INHIBIT SARS-COV-2 REPLICATION IN VERO E6 CELLS BUT NOT IN HUMAN PRIMARY AIRWAY EPITHELIUM CELLS

Autor: Leonie Apperloo, Djoke van Gosliga, Nilima Dinesh Kumar, Jolanda M. Smit, Ellen M Bouma, Martijn C. Nawijn, Denise P. I. van de Pol, Orestes A Carpaij, Ymkje Stienstra, Maarten van den Berge, Bram M. ter Ellen, Berit Troost, Heidi van der Ende-Metselaar, Izabela A. Rodenhuis-Zybert

Publikováno v: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, 66(1):e01543-21. AMER SOC MICROBIOLOGY

Antiviral therapies are urgently needed to treat and limit the development of severe COVID-19 disease. Ivermectin, a broad-spectrum anti-parasitic agent, has been shown to have anti-SARS-CoV-2 activity in Vero cells at a concentration of 5 µM. These

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ddc884316be65fe45ef42d0792b7e17

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TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis

Autor: Izabela A. Rodenhuis-Zybert, Vinit Upasani, Bram M. ter Ellen, Mariana Ruiz-Silva, Rithy Choeung, Jill Moser, Mindaugas Pauzuolis, Denis R. St. Laurent, Tineke Cantaert, Philippe Dussart, José Alberto Aguilar-Briseño, Sothy Heng, Jolanda M. Smit

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.3177. ⟨10.1038/s41467-020-16849-7⟩
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, 11(1):3177. Nature Publishing Group

Vascular permeability and plasma leakage are immune-pathologies of severe dengue virus (DENV) infection, but the mechanisms underlying the exacerbated inflammation during DENV pathogenesis are unclear. Here, we demonstrate that TLR2, together with it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208ffd5bdf01936c1e26cb9d9b748d7d
https://hal-riip.archives-ouvertes.fr/pasteur-03221719

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