Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bram Luiken"'
Autor:
Annelieke Zeilemaker, Marnie E. Blewitt, Stefan Fröhling, Remco Hoogenboezem, Christoffer Flensburg, Edward Chew, Mathijs A. Sanders, Ian J. Majewski, François G. Kavelaars, Melissa Rijken, Tamara J. McLennan, Andrew W. Roberts, Bram Luiken, Ashish Bajel, Sarah E. Miller, Adil S.A. Al Hinai, Eric M.J. Bindels, Warren S. Alexander, Peter J. M. Valk, Bob Löwenberg
Publikováno v:
Blood, 132(14), 1526-1534. American Society of Hematology
The tendency of 5-methylcytosine (5mC) to undergo spontaneous deamination has had a major role in shaping the human genome, and this methylation damage remains the primary source of somatic mutations that accumulate with age. How 5mC deamination cont
Autor:
Annelieke Zeilemaker, Sarah E. Miller, Marnie E. Blewitt, Ashish Bajel, Andrew W. Roberts, Remco Hoogenboezem, Christoffer Flensburg, Melissa Rijken, Eric M.J. Bindels, Tamara J. McLennan, François G. Kavelaars, Bram Luiken, Edward Chew, Peter J. M. Valk, Ian J. Majewski, Mathijs A. Sanders, al Hinai As, Bob Löwenberg, Warren S. Alexander
Cytosine methylation is essential for normal mammalian development, yet also provides a major mutagenic stimulus. Methylcytosine (5mC) is prone to spontaneous deamination, which introduces cytosine to thymine transition mutations (C>T) upon replicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c16f6302b155302ca46d4d5f69c389e
P083 Automation of the NGSGO library preparation for 96 and 192 samples on the Biomek I7 workstation
Autor:
Shilpa Parakh, Bram Luiken, Remco Malesatein, Maarten T. Penning, Elena Tavkin, Sake van Wageningen, Alisa Jackson
Publikováno v:
Human Immunology. 80:115
Publikováno v:
Human Immunology. 80:54
Autor:
Bram Luiken, Erik H. Rozemuller, H.W. M. van Deutekom, Remco Malestein, Maarten T. Penning, Evelien E. Bouwmans
Publikováno v:
HemaSphere. 3:340
Autor:
Gayatri C. Tetar, Maarten T. Penning, Shilpa Parakh, Wendy Swelsen, Sake van Wageningen, Elena Tavkin, Neubury M. Lardy, Alisa Jackson, Bram Luiken, Debby Krom, Joseph Lu
Publikováno v:
Human Immunology. 79:128
Aim The GenDx NGSgo workflow for HLA typing using Next-generation sequencing (NGS) consists of four practical steps: amplification, library preparation, sequencing and data analysis. Out of these four steps the library preparation is the most labor i
Autor:
Sarah E. Miller, Bob Löwenberg, Melissa Rijken, Warren S. Alexander, Tamara J. McLennan, Ian J. Majewski, François G. Kavelaars, Mathijs A. Sanders, Andrew W. Roberts, Christoffer Flensburg, Peter J. M. Valk, Annelieke Zeilemaker, Remco Hoogenboezem, Marnie E. Blewitt, Eric M.J. Bindels, Bram Luiken, Edward Chew, Ashish Bajel, Adil S.A. Al Hinai
Publikováno v:
Cancer Research. 78:1366-1366
Spontaneous methylcytosine (5mC) deamination is a common source of cytosine to thymine (C>T) mutations. These mutations accumulate over time, serving as a “molecular clock” that tracks cellular age. MBD4 is a thymine glycosylase that recognises s
Publikováno v:
Human Immunology. 78:78
Aim Accurate monitoring of the chimeric status of patients after stem cell transplantation is essential for early detection of transplant rejection or relapse. Currently, micro-chimerism levels are mostly assessed by Short Tandem Repeat (STR) fragmen
Publikováno v:
Human Immunology. 76:88
Aim To overcome the sensitivity and analysis shortcomings of STR-based transplant monitoring methods, and to improve upon the current state of the art in qPCR-based chimerism analysis, KimerDx has developed a new assay and software suite. Method Our