Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Bram G Janssen"'
Autor:
Charlotte Van Der Stukken, Tim S Nawrot, Congrong Wang, Wouter Lefebvre, Charlotte Vanpoucke, Michelle Plusquin, Harry A Roels, Bram G Janssen, Dries S. Martens
Publikováno v:
Environment International, Vol 171, Iss , Pp 107695- (2023)
Background: Particulate matter (PM) is associated with aging markers at birth, including telomeres and mitochondria. It is unclear whether markers of the core-axis of aging, i.e. tumor suppressor p53 (p53) and peroxisome proliferator-activated recept
Externí odkaz:
https://doaj.org/article/906d8a9bc9a448d9bded683a2dc4aedb
Autor:
Kristof Y Neven, MSc, Nelly D Saenen, PhD, Letitzia Tarantini, MSc, Bram G Janssen, PhD, Wouter Lefebvre, PhD, Charlotte Vanpoucke, MSc, Valentina Bollati, ProfPhD, Tim S Nawrot, ProfPhD
Publikováno v:
The Lancet Planetary Health, Vol 2, Iss 4, Pp e174-e183 (2018)
Summary: Background: Exposure to particulate air pollution has been linked with risk of carcinogenesis. Damage to repair pathways might have long-term adverse health effects. We aimed to investigate the association of prenatal exposure to air polluti
Externí odkaz:
https://doaj.org/article/1feb514263574144a4988b56f08beb0b
Publikováno v:
Epigenetics, Vol 16, Iss 2, Pp 121-131 (2021)
While previous studies have demonstrated that prenatal exposure to environmental stressors is associated with mitochondrial DNA (mtDNA) methylation, more recent investigations are questioning the accuracy of the methylation assessment and its biologi
Externí odkaz:
https://doaj.org/article/28295c797e894448a67eb89cf3d1fbe5
Autor:
Esmée M. Bijnens, Catherine Derom, Steven Weyers, Bram G. Janssen, Evert Thiery, Tim S. Nawrot
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-9 (2019)
Abstract Background Developmental processes in the placenta and the fetal brain are shaped by the similar biological signals. Evidence accumulates that adaptive responses of the placenta may influence central nervous system development. We hypothesiz
Externí odkaz:
https://doaj.org/article/0cfab73ab7794db2b60099710749245a
Autor:
Charlotte Cosemans, Congrong Wang, Dries S. Martens, Bram G. Janssen, Charlotte Vanpoucke, Wouter Lefebvre, Karen Smeets, Tim S. Nawrot, Michelle Plusquin
Publikováno v:
Environmental Science & Technology. 57:350-359
Autor:
Ellen Winckelmans, Karen Vrijens, Maria Tsamou, Bram G. Janssen, Nelly D. Saenen, Harry A. Roels, Jos Kleinjans, Wouter Lefebvre, Charlotte Vanpoucke, Theo M. de Kok, Tim S. Nawrot
Publikováno v:
Environmental Health, Vol 16, Iss 1, Pp 1-17 (2017)
Abstract Background Air pollution exposure during pregnancy has been associated with adverse birth outcomes and health problems later in life. We investigated sex-specific transcriptomic responses to gestational long- and short-term exposure to parti
Externí odkaz:
https://doaj.org/article/8fc6aae16a5e4b90b3888ef4dcb85942
Autor:
Charlotte Cosemans, Congrong Wang, Rossella Alfano, Dries S. Martens, Hanne Sleurs, Yinthe Dockx, Kenneth Vanbrabant, Bram G. Janssen, Charlotte Vanpoucke, Wouter Lefebvre, Karen Smeets, Tim S. Nawrot, Michelle Plusquin
Publikováno v:
Environmental Health. 21
Background Mitochondria play an important role in the energy metabolism and are susceptible to environmental pollution. Prenatal air pollution exposure has been linked with childhood obesity. Placental mtDNA mutations have been associated with prenat
Publikováno v:
Epigenetics
article-version (VoR) Version of Record
article-version (VoR) Version of Record
While previous studies have demonstrated that prenatal exposure to environmental stressors is associated with mitochondrial DNA (mtDNA) methylation, more recent investigations are questioning the accuracy of the methylation assessment and its biologi
Pre-admission air pollution exposure prolongs the duration of ventilation in intensive care patients
Autor:
Tim S. Nawrot, Omar El Salawi, Charlotte Vanpoucke, Walter Verbrugghe, Bianca Cox, Annick De Weerdt, Margot Jans, Esmée M. Bijnens, Bram G. Janssen, Philippe G. Jorens, Wouter Lefebvre
Publikováno v:
Intensive Care Medicine
Intensive care medicine
Intensive care medicine
Purpose Air pollutant exposure constitutes a serious risk factor for the emergence or aggravation of (existing) pulmonary disease. The impact of pre-intensive care ambient air pollutant exposure on the duration of artificial ventilation was, however,
Autor:
Dries S. Martens, Adrian Covaci, Annette Vriens, Vera Nelen, Elly Den Hond, Sam De Craemer, Michelle Plusquin, Thomas Schettgen, Greet Schoeters, Bram G. Janssen, Tim S. Nawrot, Stefaan De Henauw, Willy Baeyens, Liesbeth Bruckers, Ilse Loots
Publikováno v:
Environmental science and technology
Mitochondria] DNA (mtDNA) content and telomere length are putative aging biomarkers and are sensitive to environmental stressors, including pollutants. Our objective was to identify, from a set of environmental exposures, which exposure is associated