Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Bram C. J. van der Eerden"'
Autor:
Ariadne Bosman, W. Nadia H. Koek, Natalia Campos-Obando, Bram C. J. van der Eerden, M. A. Ikram, André G. Uitterlinden, Johannes P. T. M. van Leeuwen, M. C. Zillikens
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Sex differences in serum phosphate and calcium have been reported but the exact nature and underlying regulatory mechanisms remain unclear. We aimed to compare calcium and phosphate concentrations between sexes, and explore potential covaria
Externí odkaz:
https://doaj.org/article/73cdc742487d446cad10ed487b8298e8
Autor:
Shuang Zhang, Jeroen van de Peppel, Marijke Koedam, Johannes P. T. M. van Leeuwen, Bram C. J. van der Eerden
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background Recent evidence suggests that accumulation of marrow adipose tissue induced by aberrant lineage allocation of bone marrow-derived mesenchymal stromal cells (BMSCs) contributes to the pathophysiologic processes of osteoporosis. Alt
Externí odkaz:
https://doaj.org/article/77502ca1f7bc408e9ed5ddab9acddfbe
Autor:
Noreen Mumtaz, Marijke Koedam, Johannes P. T. M. van Leeuwen, Marion P. G. Koopmans, Bram C. J. van der Eerden, Barry Rockx
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 1621-1634 (2022)
Bone-related complications are commonly reported following arbovirus infection. These arboviruses are known to disturb bone-remodeling and induce inflammatory bone loss via increased activity of bone resorbing osteoclasts (OCs). We previously showed
Externí odkaz:
https://doaj.org/article/9800a21cf53445d5bcde625755c92e1f
Autor:
Barbara Voraberger, Johannes A. Mayr, Nadja Fratzl-Zelman, Stéphane Blouin, Suma Uday, Robert Kopajtich, Marijke Koedam, Helena Hödlmayr, Saskia B. Wortmann, Bernhard Csillag, Holger Prokisch, Bram C. J. van der Eerden, Ahmed El-Gazzar, Wolfgang Högler
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Bi-allelic variants in ASCC1 cause the ultrarare bone fragility disorder “spinal muscular atrophy with congenital bone fractures-2” (SMABF2). However, the mechanism by which ASCC1 dysfunction leads to this musculoskeletal condition and the nature
Externí odkaz:
https://doaj.org/article/4a17473717f247b2b3e96b896af55a6c
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/42268edd2e4946a0957157d955f66356
Autor:
Barnabas P. Ilenwabor, Heidi Schigt, Andreas Kompatscher, Caro Bos, Malou Zuidscherwoude, Bram C. J. van der Eerden, Joost G. J. Hoenderop, Jeroen H. F. de Baaij
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Autosomal dominant mutations in FAM111A are causative for Kenny-Caffey syndrome type 2. Patients with Kenny-Caffey syndrome suffer from severe growth retardation, skeletal dysplasia, hypoparathyroidism, hypocalcaemia, hyperphosphataemia and
Externí odkaz:
https://doaj.org/article/6bb0d67424d841f29a387deff5e3e7ee
Autor:
Shuang Zhang, Nicholas Lyons, Marijke Koedam, Jeroen van de Peppel, Johannes P.T.M. van Leeuwen, Bram C. J. van der Eerden
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Several physiological and pathological conditions such as aging, obesity, diabetes, anorexia nervosa are associated with increased adipogenesis in the bone marrow. A lack of effective drugs hinder the improved treatment for aberrant accumulation of b
Externí odkaz:
https://doaj.org/article/2fa104be394e48ceb5bac3ab0764c218
Autor:
Natalia Campos‐Obando, Ariadne Bosman, Maryam Kavousi, Carolina Medina‐Gomez, Bram C. J. van der Eerden, Daniel Bos, Oscar H. Franco, André G. Uitterlinden, M. Carola Zillikens
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 15 (2022)
Background Hyperphosphatemia has been associated with coronary artery calcification (CAC) mostly in chronic kidney disease, but the association between phosphate levels within the normal phosphate range and CAC is unclear. Our objectives were to eval
Externí odkaz:
https://doaj.org/article/7a1b7a53140b46c492daf7cb0d63e6fc
Autor:
Wida Razawy, Celso H. Alves, Marijke Koedam, Patrick S. Asmawidjaja, Adriana M. C. Mus, Mohamed Oukka, Pieter J. M. Leenen, Jenny A. Visser, Bram C. J. van der Eerden, Erik Lubberts
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The IL-23 receptor (IL-23R) signaling pathway has pleiotropic effects on the differentiation of osteoclasts and osteoblasts, since it can inhibit or stimulate these processes via different pathways. However, the potential role of this pathwa
Externí odkaz:
https://doaj.org/article/4178bd5619304f8498fcb69ed29bb6bc
Autor:
Gijs A. C. Franken, Murat Seker, Caro Bos, Laura A. H. Siemons, Bram C. J. van der Eerden, Annabel Christ, Joost G. J. Hoenderop, René J. M. Bindels, Dominik Müller, Tilman Breiderhoff, Jeroen H. F. de Baaij
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Patients with mutations in Cyclin M2 (CNNM2) suffer from hypomagnesaemia, seizures, and intellectual disability. Although the molecular function of CNNM2 is under debate, the protein is considered essential for renal Mg2+ reabsorption. Here,
Externí odkaz:
https://doaj.org/article/425e0fafae4846bc82edea83d0b50985