Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Bram, Gerritsen"'
Autor:
Joann Diray-Arce, Helen E. R. Miller, Evan Henrich, Bram Gerritsen, Matthew P. Mulè, Slim Fourati, Jeremy Gygi, Thomas Hagan, Lewis Tomalin, Dmitry Rychkov, Dmitri Kazmin, Daniel G. Chawla, Hailong Meng, Patrick Dunn, John Campbell, The Human Immunology Project Consortium (HIPC), Minnie Sarwal, John S. Tsang, Ofer Levy, Bali Pulendran, Rafick Sekaly, Aris Floratos, Raphael Gottardo, Steven H. Kleinstein, Mayte Suárez-Fariñas
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-16 (2022)
Measurement(s) Transcriptomics • Hemagglutination Inhibition Assay • IgG IgM IgA Total Measurement • Virus-neutralizing Antibody • ELISA Technology Type(s) Microarray • RNA sequencing • Hemagglutination Inhibition Assay • ELISA • Micr
Externí odkaz:
https://doaj.org/article/e29b684ada444c44833f7762240235b8
Autor:
Yujiao Zhao, Matthew Amodio, Brent Vander Wyk, Bram Gerritsen, Mahesh M Kumar, David van Dijk, Kevin Moon, Xiaomei Wang, Anna Malawista, Monique M Richards, Megan E Cahill, Anita Desai, Jayasree Sivadasan, Manjunatha M Venkataswamy, Vasanthapuram Ravi, Erol Fikrig, Priti Kumar, Steven H Kleinstein, Smita Krishnaswamy, Ruth R Montgomery
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 3, p e0008112 (2020)
The genus Flavivirus contains many mosquito-borne human pathogens of global epidemiological importance such as dengue virus, West Nile virus, and Zika virus, which has recently emerged at epidemic levels. Infections with these viruses result in diver
Externí odkaz:
https://doaj.org/article/b845d9f70c124f9aaf91dca3f01f7623
Autor:
Peter C de Greef, Theres Oakes, Bram Gerritsen, Mazlina Ismail, James M Heather, Rutger Hermsen, Benjamin Chain, Rob J de Boer
Publikováno v:
eLife, Vol 9 (2020)
The clone size distribution of the human naive T-cell receptor (TCR) repertoire is an important determinant of adaptive immunity. We estimated the abundance of TCR sequences in samples of naive T cells from blood using an accurate quantitative sequen
Externí odkaz:
https://doaj.org/article/97a56772865248cc95c8c2981abdc580
Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination
Autor:
Slim, Fourati, Lewis E, Tomalin, Matthew P, Mulè, Daniel G, Chawla, Bram, Gerritsen, Dmitry, Rychkov, Evan, Henrich, Helen E R, Miller, Thomas, Hagan, Joann, Diray-Arce, Patrick, Dunn, Ofer, Levy, Raphael, Gottardo, Minnie M, Sarwal, John S, Tsang, Mayte, Suárez-Fariñas, Bali, Pulendran, Steven H, Kleinstein, Alkis, Togias
Publikováno v:
Nature Immunology. 23:1777-1787
Several studies have shown that the pre-vaccination immune state is associated with the antibody response to vaccination. However, the generalizability and mechanisms that underlie this association remain poorly defined. Here, we sought to identify a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd8319e180e93c109adce90301b00b6
https://doi.org/10.1038/s41590-022-01329-5
https://doi.org/10.1038/s41590-022-01329-5
Autor:
Patricia A. Possik, Judith Müller, Carmen Gerlach, Juliana C.N. Kenski, Xinyao Huang, Aida Shahrabi, Oscar Krijgsman, Ji-Ying Song, Marjon A. Smit, Bram Gerritsen, Cor Lieftink, Kristel Kemper, Magali Michaut, Roderick L. Beijersbergen, Lodewyk Wessels, Ton N. Schumacher, Daniel S. Peeper
Publikováno v:
Cell Reports, Vol 9, Iss 4, Pp 1375-1386 (2014)
To identify factors preferentially necessary for driving tumor expansion, we performed parallel in vitro and in vivo negative-selection short hairpin RNA (shRNA) screens. Melanoma cells harboring shRNAs targeting several DNA damage response (DDR) kin
Externí odkaz:
https://doaj.org/article/a4a4973345cf4a9daafaab7b6cdd3545
Autor:
Thomas, Hagan, Bram, Gerritsen, Lewis E, Tomalin, Slim, Fourati, Matthew P, Mulè, Daniel G, Chawla, Dmitri, Rychkov, Evan, Henrich, Helen E R, Miller, Joann, Diray-Arce, Patrick, Dunn, Audrey, Lee, Ofer, Levy, Raphael, Gottardo, Minne M, Sarwal, John S, Tsang, Mayte, Suárez-Fariñas, Rafick-Pierre, Sékaly, Steven H, Kleinstein, J S, Tsang
Publikováno v:
Nature immunology. 23(12)
Systems vaccinology has defined molecular signatures and mechanisms of immunity to vaccination. However, comparative analysis of immunity to different vaccines is lacking. We integrated transcriptional data of over 3,000 samples, from 820 adults acro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::28e82f406ef6fae921fca14081dca96b
https://pubmed.ncbi.nlm.nih.gov/36443516
https://pubmed.ncbi.nlm.nih.gov/36443516
Autor:
Minnie M. Sarwal, Patrick Dunn, Evan Henrich, Ofer Levy, Raphael Gottardo, Aris Floratos, Joann Diray-Arce, Bram Gerritsen, John N. Campbell, Hailong Meng, Mayte Suárez-Fariñas, Dmitri Kazmin, Lewis Tomalin, Jeremy Gygi, Rafick Pierre Sekaly, Daniel G. Chawla, Steven H. Kleinstein, Slim Fourati, Bali Pulendran, Matthew P. Mulé, Helen E.R. Miller, Thomas Hagan, Dmitry Rychkov, John S. Tsang
Vaccines are among the most cost-effective public health interventions for preventing infection-induced morbidity and mortality, yet much remains to be learned regarding the mechanisms by which vaccines protect. Systems immunology combines traditiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adcf2c7e880b9607cd3a5de3b52b4627
https://doi.org/10.1101/2021.11.05.465336
https://doi.org/10.1101/2021.11.05.465336
Autor:
Patrick Dunn, Ofer Levy, Raphael Gottardo, E. Henrich, Bram Gerritsen, Joann Diray-Arce, Rp. Sékaly, Mayte Suárez-Fariñas, Her. Miller, Slim Fourati, Minnie M. Sarwal, Dmitry Rychkov, Mp. Mulè, John S. Tsang, Bali Pulendran, Thomas Hagan, Dg. Chawla, Le. Tomalin, Sh. Kleinstein
Many factors determine whether an individual responding to vaccination will generate an immune response that can lead to protection. Several studies have shown that the pre-vaccination immune state is associated with the antibody response to vaccines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ddec182b555c053ecd6b12acbfb21d5
https://doi.org/10.1101/2021.09.26.461847
https://doi.org/10.1101/2021.09.26.461847
Autor:
Aridaman Pandit, Bram Gerritsen
Publikováno v:
Immunology & Cell Biology. 94:236-241
CD8(+) T cells have an important role in protection against infections and reinfections of intra-cellular pathogens like viruses. Naive CD8(+) T cells circulating in blood or lymphoid tissues can get activated upon stimulation by cognate antigen. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baaa6c46e66091784c64aa8c6fd0293f
https://doi.org/10.1038/icb.2015.118
https://doi.org/10.1038/icb.2015.118