Zobrazeno 1 - 10
of 1 408
pro vyhledávání: '"Brain microvascular endothelial cells"'
Autor:
Rodrigo Azevedo Loiola, Johan Hachani, Sophie Duban-Deweer, Emmanuel Sevin, Paulina Bugno, Agnieszka Kowalska, Eleonora Rizzi, Fumitaka Shimizu, Takashi Kanda, Caroline Mysiorek, Maciej Mazurek, Fabien Gosselet
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-23 (2024)
Abstract Cell-based therapeutic strategies have been proposed as an alternative for brain and blood vessels repair after stroke, but their clinical application is hampered by potential adverse effects. We therefore tested the hypothesis that secretom
Externí odkaz:
https://doaj.org/article/3fdd9b198ef94d4688410eae49a4a9e2
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Endothelial progenitor cells (EPCs) play a crucial role in maintaining vascular health and aiding in the repair of damaged blood vessels. However, the specific impact of EPCs-derived exosomes on vascular endothelial cell injury caused by lip
Externí odkaz:
https://doaj.org/article/2754664e0b614410aada89b7e26a42a5
Autor:
Surachai Ngamratanapaiboon, Napatarin Srikornvit, Patipol Hongthawonsiri, Krittaboon Pornchokchai, Siriphattarinya Wongpitoonmanachai, Jiajun Mo, Petchlada Pholkla, Pracha Yambangyang, Phichanan Duchda, Jenyuk Lohwacharin, Watcharaporn Devakul Na Ayutthaya
Publikováno v:
Toxicology Reports, Vol 13, Iss , Pp 101691- (2024)
Risperidone is useful for the treatment of schizophrenia symptoms; however, it also has side effects, and an overdose can be harmful. The metabolic effects of risperidone at high therapeutic doses and its metabolites have not been elucidated. Endogen
Externí odkaz:
https://doaj.org/article/6201f2477e284e24b5706f0dc952d882
Autor:
Adnan Gopinadhan, Jason M. Hughes, Andrea L. Conroy, Chandy C. John, Scott G. Canfield, Dibyadyuti Datta
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Background Blood–brain barrier (BBB) disruption is a central feature of cerebral malaria (CM), a severe complication of Plasmodium falciparum (Pf) infections. In CM, sequestration of Pf-infected red blood cells (Pf-iRBCs) to brain endothel
Externí odkaz:
https://doaj.org/article/7d673f06ff7e46ea816437b94c0968fb
Autor:
Shigeru Yamada, Tadahiro Hashita, Shota Yanagida, Hiroyuki Sato, Yukuto Yasuhiko, Kaori Okabe, Takamasa Noda, Motohiro Nishida, Tamihide Matsunaga, Yasunari Kanda
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), which is associated with various neurological symptoms, including nausea, dizziness, headache, encephalitis, and epileptic se
Externí odkaz:
https://doaj.org/article/bd61bb35f58e48ee99829224059da9e7
Autor:
Xiaojun Deng, Xiaoyi Hu, Shang Wang, Hui Zhao, Yaqin Wei, Jiaqi Fu, Wenhui Wu, Jinming Liu, Caicai Zhang, Lili Wang, Ping Yuan
Publikováno v:
Animal Models and Experimental Medicine, Vol 7, Iss 1, Pp 24-35 (2024)
Abstract Background Our previous study found that mouse embryonic neural stem cell (NSC)–derived exosomes (EXOs) regulated NSC differentiation via the miR‐9/Hes1 axis. However, the effects of EXOs on brain microvascular endothelial cell (BMEC) dy
Externí odkaz:
https://doaj.org/article/aac09ceaa0774769ad435a63f629f04e
Autor:
Jinrui Sun, Ruicheng Yang, Jiyang Fu, Dong Huo, Xinyi Qu, Chen Tan, Huanchun Chen, Xiangru Wang
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Meningitic Escherichia coli (E. coli) is the major etiological agent of bacterial meningitis, a life-threatening infectious disease with severe neurological sequelae and high mortality. The major cause of central nervous system (C
Externí odkaz:
https://doaj.org/article/97fbb1913a2d4ba7ba9e2850aebaca3a
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 6, Pp 1344-1350 (2024)
[INLINE:1] Post-acute ischemic stroke hyperglycemia increases the risk of hemorrhagic transformation, which is associated with blood-brain barrier disruption. Brain microvascular endothelial cells are a major component of the blood-brain barrier. Int
Externí odkaz:
https://doaj.org/article/aa3b2d912aba4290a58afb193f49d136
Publikováno v:
Jichu yixue yu linchuang, Vol 43, Iss 11, Pp 1631-1635 (2023)
Objective To explore the effects and mechanism of methylglyoxal (MGO) in human brain microvascular endothelial cell line (hCMEC/D3). Methods The hCMEC/D3 cells were incubated with MGO(0.25, 0.50, 0.75, 1.00 and 1.25 mmol/L) for 24 h. Cell viability w
Externí odkaz:
https://doaj.org/article/af6d7043292449ab8de6b5633b26d513
Autor:
Chiara Stüdle, Hideaki Nishihara, Sven Wischnewski, Laila Kulsvehagen, Sylvain Perriot, Hiroshi Ishikawa, Horst Schroten, Stephan Frank, Nikolaus Deigendesch, Renaud Du Pasquier, Lucas Schirmer, Anne-Katrin Pröbstel, Britta Engelhardt
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-21 (2023)
Abstract Background As a consequence of SARS-CoV-2 infection various neurocognitive and neuropsychiatric symptoms can appear, which may persist for several months post infection. However, cell type-specific routes of brain infection and underlying me
Externí odkaz:
https://doaj.org/article/d9433b49b0e545ddb46501b777be8935