Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Brain microenvironment"'
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Breast cancer is the leading cancer diagnosed in women globally, with brain metastasis emerging as a major cause of death, particularly in human epidermal growth factor receptor 2 positive and triple-negative breast cancer subtypes. Comprehensive und
Externí odkaz:
https://doaj.org/article/93c1a938f4c54d1d9773eda08d321050
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Breast cancer is the most frequent malignancy in women, constituting 15.2% of all new cancers diagnosed in the United States. Distant breast cancer metastasis accounts for the majority of breast cancer-related deaths; brain metastasis is the third mo
Externí odkaz:
https://doaj.org/article/67bd97ec0b3a4b42868e8652916f06e6
Autor:
Michael McKenna, Jeremy R. Filteau, Brendan Butler, Kenneth Sluis, Michael Chungyoun, Nels Schimek, Elizabeth Nance
Publikováno v:
Journal of Biological Engineering, Vol 16, Iss 1, Pp 1-22 (2022)
Abstract Background The brain extracellular environment is involved in many critical processes associated with neurodevelopment, neural function, and repair following injury. Organization of the extracellular matrix and properties of the extracellula
Externí odkaz:
https://doaj.org/article/2e9e5164c35b4efebe66d0986b646b78
Autor:
Asad Ur Rehman, Parvez Khan, Shailendra Kumar Maurya, Jawed A. Siddiqui, Juan A. Santamaria-Barria, Surinder K. Batra, Mohd Wasim Nasser
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-20 (2022)
Abstract Brain metastasis (BrM) is a major problem associated with cancer-related mortality, and currently, no specific biomarkers are available in clinical settings for early detection. Liquid biopsy is widely accepted as a non-invasive method for d
Externí odkaz:
https://doaj.org/article/a342a78c37b14c9fac985a0241c7c12e
Autor:
Elliya Park, Lily Yi Li, Chunsheng He, Azhar Z. Abbasi, Taksim Ahmed, Warren D. Foltz, Regan O'Flaherty, Maham Zain, Robert P. Bonin, Andrew M. Rauth, Paul E. Fraser, Jeffrey T. Henderson, Xiao Yu Wu
Publikováno v:
Advanced Science, Vol 10, Iss 12, Pp n/a-n/a (2023)
Abstract Finding effective disease‐modifying treatment for Alzheimer's disease remains challenging due to an array of factors contributing to the loss of neural function. The current study demonstrates a new strategy, using multitargeted bioactive
Externí odkaz:
https://doaj.org/article/00664533c62e4fa0a99ec8433353bc08
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
The incidence of brain metastases (BrM) has become a growing concern recently. It is a common and often fatal manifestation in the brain during the end-stage of many extracranial primary tumors. Increasing BrM diagnoses can be attributed to improveme
Externí odkaz:
https://doaj.org/article/b5ea1c67e8a3497e9d0c27da87036605
Autor:
Lisa R. Decotret, Rocky Shi, Kiersten N. Thomas, Manchi Hsu, Catherine J. Pallen, Kevin L. Bennewith
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Organotypic cultures of murine brain slices are well-established tools in neuroscience research, including electrophysiology studies, modeling neurodegeneration, and cancer research. Here, we present an optimized ex vivo brain slice invasion assay th
Externí odkaz:
https://doaj.org/article/8df087dba80a434fb6e21bfef215d29d
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/a21d245d6af046709c0315ce2d6d210a
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Brain metastasis of a cancer is a malignant disease with high mortality, but the cause and the molecular mechanism remain largely unknown. Using the samples of primary tumors of 22 cancer types in the TCGA database, we have performed a computational
Externí odkaz:
https://doaj.org/article/e3182d9c2b2647ad960d61aa546bc9da
