Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Brain insulin signaling"'
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 22, Pp 237-249 (2023)
Poor cognitive ability is a consequence of a wide variety of neurobehavioral disorders and is a growing health problem, especially among the elderly and patients with diabetes. The precise underlying cause of this complication is not well-defined. Ho
Externí odkaz:
https://doaj.org/article/15876505fb3a40f0bd4cfcb03639576f
Autor:
Matthäus Metz, James O'Hare, Bob Cheng, Michelle Puchowicz, Christoph Buettner, Thomas Scherer
Publikováno v:
Molecular Metabolism, Vol 73, Iss , Pp 101723- (2023)
Objectives: Insulin's ability to counterbalance catecholamine-induced lipolysis defines insulin action in adipose tissue. Insulin suppresses lipolysis directly at the level of the adipocyte and indirectly through signaling in the brain. Here, we furt
Externí odkaz:
https://doaj.org/article/8cd03a65b14245de85da4286aaef9d59
Autor:
Kristina Wardelmann, Michaela Rath, José Pedro Castro, Sabine Blümel, Mareike Schell, Robert Hauffe, Fabian Schumacher, Tanina Flore, Katrin Ritter, Andreas Wernitz, Toru Hosoi, Koichiro Ozawa, Burkhard Kleuser, Jürgen Weiß, Annette Schürmann, André Kleinridders
Publikováno v:
Antioxidants, Vol 10, Iss 5, p 711 (2021)
Mitochondria are critical for hypothalamic function and regulators of metabolism. Hypothalamic mitochondrial dysfunction with decreased mitochondrial chaperone expression is present in type 2 diabetes (T2D). Recently, we demonstrated that a dysregula
Externí odkaz:
https://doaj.org/article/9db7b1040f554f3f80b1b7f6dd84a90e
Autor:
Yaribeygi, Habib, Maleki, Mina, Butler, Alexandra E., Jamialahmadi, Tannaz, Sahebkar, Amirhossein
Poor cognitive ability is a consequence of a wide variety of neurobehavioral disorders and is a growing health problem, especially among the elderly and patients with diabetes. The precise underlying cause of this complication is not well-defined. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a27b1954524eff6c18d0e809e8cb908f
Akademický článek
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Akademický článek
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Autor:
Robert Hauffe, C. Ronald Kahn, Eugenia Alfine, Jürgen Weiß, Tanina Flore, Kathrin Warnke, Michaela Rath, Chantal Chudoba, Mareike Schell, Weikang Cai, Sabine Blümel, Kristina Wardelmann, Katrin Ritter, André Kleinridders
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 21, Iss, Pp 68-81 (2019)
Molecular Metabolism, Vol 21, Iss, Pp 68-81 (2019)
Objective Insulin action in the brain controls metabolism and brain function, which is linked to proper mitochondrial function. Conversely, brain insulin resistance associates with mitochondrial stress and metabolic and neurodegenerative diseases. In
Autor:
Yanxing eChen, Xiaoqin eRun, Zhihou eLiang, Yang eZhao, CHUN-LING eDAI, Khalid eIqbal, Fei eLiu, CHENG-XIN eGONG
Publikováno v:
Frontiers in Aging Neuroscience, Vol 6 (2014)
Background: It is well documented that elderly individuals are at increased risk of cognitive decline after anesthesia. General anesthesia is believed to be a risk factor for Alzheimer’s disease (AD). Recent studies suggest that anesthesia may incr
Externí odkaz:
https://doaj.org/article/8a51a9a596944cb1b014806481fb5b52
Autor:
Wardelmann, Kristina, Rath, Michaela, Castro, José Pedro, Blümel, Sabine, Schell, Mareike, Hauffe, Robert, Schumacher, Fabian, Flore, Tanina, Ritter, Katrin, Wernitz, Andreas, Hosoi, Toru, Ozawa, Koichiro, Kleuser, Burkhard, Weiß, Jürgen, Schürmann, Annette, Kleinridders, André
Publikováno v:
Antioxidants, Vol 10, Iss 711, p 711 (2021)
Antioxidants
Antioxidants, 10(5):711
Volume 10
Issue 5
Antioxidants
Antioxidants, 10(5):711
Volume 10
Issue 5
Mitochondria are critical for hypothalamic function and regulators of metabolism. Hypothalamic mitochondrial dysfunction with decreased mitochondrial chaperone expression is present in type 2 diabetes (T2D). Recently, we demonstrated that a dysregula