Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Brain infiltration"'
Autor:
Clara Muñoz-Castro, Marina Mejias-Ortega, Elisabeth Sanchez-Mejias, Victoria Navarro, Laura Trujillo-Estrada, Sebastian Jimenez, Juan Antonio Garcia-Leon, Juan Jose Fernandez-Valenzuela, Maria Virtudes Sanchez-Mico, Carmen Romero-Molina, Ines Moreno-Gonzalez, David Baglietto-Vargas, Marisa Vizuete, Antonia Gutierrez, Javier Vitorica
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-21 (2023)
Abstract Microglia are brain-resident myeloid cells and play a major role in the innate immune responses of the CNS and the pathogenesis of Alzheimer's disease (AD). However, the contribution of nonparenchymal or brain-infiltrated myeloid cells to di
Externí odkaz:
https://doaj.org/article/4356ba8ee739486f92b38c01b92e57e2
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Brain infiltration of the natural killer (NK) cells has been observed in several neurodegenerative disorders, including Parkinson’s disease (PD). In a mouse model of α-synucleinopathy, it has been shown that NK cells help in clearing α-synuclein
Externí odkaz:
https://doaj.org/article/e938f7af62874dacac715f552417928f
Autor:
Carlos del Pilar, Rafael Lebrón-Galán, Ester Pérez-Martín, Laura Pérez-Revuelta, Carmelo Antonio Ávila-Zarza, José Ramón Alonso, Diego Clemente, Eduardo Weruaga, David Díaz
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
The progression of neurodegenerative diseases is reciprocally associated with impairments in peripheral immune responses. We investigated different contexts of selective neurodegeneration to identify specific alterations of peripheral immune cells an
Externí odkaz:
https://doaj.org/article/1971fdd4f2dc4269806dea73b2b40141
Autor:
Francesc Miró-Mur, Xabier Urra, Francisca Ruiz-Jaén, Jordi Pedragosa, Ángel Chamorro, Anna M. Planas
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Ischemic stroke causes brain tissue damage and may release central nervous system (CNS)-specific peptides to the periphery. Neural antigen presentation in the lymphoid tissue could prime immune cells and result in adaptive immune response. However, a
Externí odkaz:
https://doaj.org/article/737dd6483a9148e48f599ed4baa11655
Autor:
David L. Bernstein, Slava Rom
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Stroke is a debilitating illness facing healthcare today, affecting over 800,000 people and causing over 140,000 deaths each year in the United States. Despite being the third-leading cause of death, very few treatments currently exist for stroke. Of
Externí odkaz:
https://doaj.org/article/3a5d5bb7852c4d608d6c1a63e15b9d2c
Autor:
Kee Wui Huang, Bernardo L. Sabatini
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Viral vectors are essential tools for the study of neural circuits, with glycoprotein-deleted rabies viruses being widely used for monosynaptic retrograde tracing to map connectivity between specific cell types in the nervous system. However, the use
Externí odkaz:
https://doaj.org/article/3992e5db7c7b4aa59f5795f5eb05b7aa
Akademický článek
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Autor:
Fang Zhang, Qiuchen Zhao, Yinghua Jiang, Ning Liu, Qiang Liu, Fu-Dong Shi, Junwei Hao, Yun Xu, Eng H. Lo, Xiaoying Wang
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Stroke patients with diabetes suffer from higher mortality rate and worsened neurological outcome. However, the responses of immune system to cerebral ischemia in the setting of diabetes remain poorly understood.Methods: In this study, we
Externí odkaz:
https://doaj.org/article/d655111b1f304fdbaddaf0aabd57f760
Akademický článek
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Akademický článek
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