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Disturbed brain energy metabolism in a rodent model of DYT-TOR1A dystonia

Autor: Susanne Knorr, Lisa Rauschenberger, Muthuraman Muthuraman, Rhonda McFleder, Thomas Ott, Kathrin Grundmann-Hauser, Takahiro Higuchi, Jens Volkmann, Chi Wang Ip

Publikováno v: Neurobiology of Disease, Vol 194, Iss , Pp 106462- (2024)

DYT-TOR1A (DYT1) dystonia, characterized by reduced penetrance and suspected environmental triggers, is explored using a “second hit” DYT-TOR1A rat model. We aim to investigate the biological mechanisms driving the conversion into a dystonic phen

Externí odkaz: https://doaj.org/article/e3e0427f360e46b5810d1e70a6ce8c05

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A tribute to Arne Schousboe's contributions to neurochemistry and his innovative and enduring research in GABA, glutamate, and brain energy metabolism.

Autor: McKenna MC; Department of Pediatrics and Program in Neuroscience, University of Maryland School of Medicine, Baltimore, Maryland, USA., Sonnewald U; Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway., Waageptersen HS; University of Southern Denmark, Odense, Denmark., White HS; Department of Pharmacy, University of Washington, Seattle, Washington, USA.

Publikováno v: Journal of neurochemistry [J Neurochem] 2025 Jan; Vol. 169 (1), pp. e16207. Date of Electronic Publication: 2024 Aug 26.