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pro vyhledávání: '"Brain Phenix"'
Autor:
Yong Liu, Yadan W. Chen, Artis Klapars, Thomas J. Novak, Lisa F. Frey, Brain Phenix, Kevin R. Campos, Cheng-yi Chen
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 49:702-710
Taranabant (MK-0364) is a highly potent and selective cannabinoid-1 receptor (CB-1R) inverse agonist. It is being developed at MerckCompany to treat obesity. The chemical synthesis of MK-0364 drug substance involved the direct coupling of chiral amin