Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Brain Ischemia/pathology"'
1
A Probable Dual Mode of Action for Both L- and D-Lactate Neuroprotection in Cerebral Ischemia
Autor: Konstantin Drandarov, Matthias T. Wyss, Ximena Castillo, Katia Rosafio, Lorenz Hirt, Alfred Buck, Luc Pellerin, Bruno Weber
Publikováno v: Journal of Cerebral Blood Flow and Metabolism, vol. 35, no. 10, pp. 1561-1569
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol. 35, no. 10, pp. 1561-1569
Lactate has been shown to offer neuroprotection in several pathologic conditions. This beneficial effect has been attributed to its use as an alternative energy substrate. However, recent description of the expression of the HCA1 receptor for lactate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08dddf3aed83e7117e18885227349575
https://doi.org/10.1038/jcbfm.2015.115
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2
Developmental Changes and Injury Induced Disruption of the Radial Organization of the Cortex in the Immature Rat Brain Revealed by In Vivo Diffusion Tensor MRI
Autor: Joel R. Garbow, Petra Susan Hüppi, Terrie E. Inder, Stéphane Sizonenko, Stephan E. Maier, Emily J. Camm, Jeffrey J. Neil, Chris E. Williams
Publikováno v: Cerebral Cortex, Vol. 17, No 11 (2007) pp. 2609-17
During brain development, morphological changes modify the cortex from its immature radial organization to its mature laminar appearance. Applying in vivo diffusion tensor imaging (DTI), the microstructural organization of the cortex in the immature
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e756386999a94d3dbb39e9945c26e7f5
http://doc.rero.ch/record/290729/files/bhl168.pdf
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3
The IMPROVE Guidelines (Ischaemia Models : Procedural Refinements Of in Vivo Experiments)
Autor: Rebecca C. Trueman, Claire L. Gibson, Isabel Pérez de Puig, Tracy D. Farr, Christopher McCabe, Anna Morancho, Hilary V O Carswell, Anna Rosell, Stuard M. Allan, Lawrence D. F. Moon, Nathalie Percie du Sert, Lindsay Gallagher, Kathryn Ryder, Anna M. Planas, Raymond C.B. Wong, Michael J. O'Neill, Malcolm R. Macleod, Mark D. Tricklebank, Emily S. Sena, C. Ian Ragan, I. Mhairi Macrae, Brad A. Sutherland, Paul A. Flecknell, Graeme A. Deuchar, Michael J. Haley, Lisa A Roy, Barry W. McColl, Alessio Alfieri, Alba Simats, Lucy Whitfield
Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Journal of Cerebral Blood Flow & Metabolism
Percie du Sert, N, Alfieri, A, Allan, S M, Carswell, H V, Deuchar, G A, Farr, T D, Flecknell, P, Gallagher, L, Gibson, C L, Haley, M J, Macleod, M R, McColl, B W, McCabe, C, Morancho, A, Moon, L DF, O'Neill, M J, Pérez de Puig, I, Planas, A, Ragan, C I, Rosell, A, Roy, L A, Ryder, K O, Simats, A, Sena, E S, Sutherland, B A, Tricklebank, M D, Trueman, R C, Whitfield, L, Wong, R & Macrae, I M 2017, ' The IMPROVE Guidelines (Ischaemia Models : Procedural Refinements Of in Vivo Experiments) ', Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol. 37, no. 11, pp. 3488-3517 . https://doi.org/10.1177/0271678X17709185
Percie du Sert, N, Alfieri, A, Allan, S M, Carswell, H V, Deuchar, G A, Farr, T D, Flecknell, P, Gallagher, L, Gibson, C L, Haley, M J, Macleod, M R, McColl, B W, McCabe, C, Morancho, A, Moon, L D, O'Neill, M J, Pérez de Puig, I, Planas, A, Ragan, C I, Rosell, A, Roy, L A, Ryder, K O, Simats, A, Sena, E S, Sutherland, B A, Tricklebank, M D, Trueman, R C, Whitfield, L, Wong, R & Macrae, I M 2017, ' The IMPROVE Guidelines (Ischaemia Models : Procedural Refinements Of in Vivo Experiments) ', Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol. 37, no. 11, pp. 3488-3517 . https://doi.org/10.1177/0271678X17709185
Digital.CSIC. Repositorio Institucional del CSIC
instname
Percie du Sert, N, Alfieri, A, Allan, S M, Carswell, H V O, Deuchar, G A, Farr, T D, Flecknell, P, Gallagher, L, Gibson, C, Haley, M J, MacLeod, M, McColl, B, McCabe, C, Morancho, A, Moon, L, O'Neill, M, Perez de Puig, I, Planas, A, Ragan, I, Rosell, A, Roy, L, Ryder, K, Simats, A, Sena, E, Sutherland, B, Tricklebank, M, Trueman, R, Whitfield, L, Wong, R & Macrae, M 2017, ' The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments ', Journal of Cerebral Blood Flow and Metabolism, vol. 37, no. 11, 271678X17709185, pp. 3488-3517 . https://doi.org/10.1177/0271678X17709185
Most in vivo models of ischaemic stroke target the middle cerebral artery and a spectrum of stroke severities, from mild to substantial, can be achieved. This review describes opportunities to improve the in vivo modelling of ischaemic stroke and ani
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf9c23a9fe51c599cd16cdb0b956f1b
https://ddd.uab.cat/record/200586
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4
Postischemic treatment of neonatal cerebral ischemia should target autophagy
Autor: Peter G.H. Clarke, Anne Vaslin, Julien Puyal, Vincent Mottier
Publikováno v: Annals of Neurology, vol. 66, no. 3, pp. 378-389
OBJECTIVE: To evaluate the contributions of autophagic, necrotic, and apoptotic cell death mechanisms after neonatal cerebral ischemia and hence define the most appropriate neuroprotective approach for postischemic therapy. METHODS: Rats were exposed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c2427855a3b98cbcd2cc72a27c2a2b
https://doi.org/10.1002/ana.21714
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5
Oxidative Stress Induction of DJ-1 Protein in Reactive Astrocytes Scavenges Free Radicals and Reduces Cell Injury
Autor: Takahiro Taira, Atsuko Yamamoto, Yoshihisa Kitamura, Kazuyuki Takata, Hiroyoshi Ariga, Shigehiro Morikawa, Takashi Taniguchi, Takashi Yanagida, Jun Tsushima, Ikuo Tooyama, Toshihiro Inubushi, Hiroyuki Yasui, Tomonori Shibaike, Daijiro Yanagisawa
Publikováno v: Oxidative Medicine and Cellular Longevity, Vol 2, Iss 1, Pp 36-42 (2009)
Scopus-Elsevier
Oxidative Medicine and Cellular Longevity
Astrocytes, one of the predominant types of glial cells, function as both supportive and metabolic cells for the brain. Under cerebral ischemia/reperfusion-induced oxidative conditions, astrocytes accumulate and activate in the ischemic region. DJ-1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14796fe400fc05fd44a82fd4d8906722
https://doaj.org/article/c951accc23ab47eba1c9ac891a885fa3
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6
Endogenous IFN-β signaling exerts anti-inflammatory actions in experimentally induced focal cerebral ischemia
Autor: Martina Svensson, Kate Lykke Lambertsen, Shohreh Issazadeh-Navikas, Yawei Liu, Bettina Hjelm Clausen, Reza Khorooshi, Totte Stankovich, Tomas Deierborg, Ana R. Inácio, Krzysztof Kucharz, Yiyi Yang
Publikováno v: Journal of Neuroinflammation
Journal of Neuroinflammation, BioMed Central, 2015, 12 (1), pp.211. ⟨10.1186/s12974-015-0427-0⟩
Inacio, A R, Liu, Y, Clausen, B H, Svensson, M, Kucharz, K, Yang, Y, Stankovich, T, Khorooshi, R M H, Lambertsen, K L, Issazadeh-Navikas, S & Deierborg, T 2015, ' Endogenous IFN-β signaling exerts anti-inflammatory actions in experimentally induced focal cerebral ischemia ', Journal of Neuroinflammation, vol. 12, 211 . https://doi.org/10.1186/s12974-015-0427-0
Background Interferon (IFN)-β exerts anti-inflammatory effects, coupled to remarkable neurological improvements in multiple sclerosis, a neuroinflammatory condition of the central nervous system. Analogously, it has been hypothesized that IFN-β, by
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163e46687cdd8b6f4037e9aca6917ea3
https://doi.org/10.1186/s12974-015-0427-0
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7
Non-invasive diagnostic biomarkers for estimating the onset time of permanent cerebral ischemia
Autor: Carole Berthet, Lara Buscemi, Corinne Benakis, Lorenz Hirt, Lijing Xin, Hongxia Lei, Rolf Gruetter
Publikováno v: Journal of Cerebral Blood Flow and Metabolism, vol. 34, no. 11, pp. 1848-1855
ResearcherID
Journal of Cerebral Blood Flow & Metabolism
Journal of Cerebral Blood Flow and Metabolism, Vol. 34, No 11 (2014) pp. 1848-1855
The treatments for ischemic stroke can only be administered in a narrow time-window. However, the ischemia onset time is unknown in ~30% of stroke patients (wake-up strokes). The objective of this study was to determine whether MR spectra of ischemic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac512f9ada91eea18c6189e22f78884
https://serval.unil.ch/notice/serval:BIB_7F4F2FC5DDE2
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8
Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia
Autor: Rhea Sumpter, Julien Puyal, Douglas R. Green, Yongjie Wei, Peter G.H. Clarke, Liying Zhang, Vanessa Ginet, Beth Levine, Sanae Shoji-Kawata, Stanley Y. Shaw, Ramnik J. Xavier, Khoa D. Tran, Bruce A. Posner, Yang Liu
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 51, pp. 20364-20371
A long-standing controversy is whether autophagy is a bona fide cause of mammalian cell death. We used a cell-penetrating autophagy-inducing peptide, Tat-Beclin 1, derived from the autophagy protein Beclin 1, to investigate whether high levels of aut
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb3dcb157ab7eea5588c5b74ef28932
https://pubmed.ncbi.nlm.nih.gov/25376517
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9
Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia
Autor: Liu, Yang, Shoji-Kawata, Sanae, Sumpter, Rhea M, Wei, Yongjie, Ginet, Vanessa, Zhang, Liying, Posner, Bruce, Tran, Khoa A, Green, Douglas R, Xavier, Ramnik J, Shaw, Stanley Y, Clarke, Peter G H, Puyal, Julien, Levine, Beth
A long-standing controversy is whether autophagy is a bona fide cause of mammalian cell death. We used a cell-penetrating autophagy-inducing peptide, Tat-Beclin 1, derived from the autophagy protein Beclin 1, to investigate whether high levels of aut
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2659::51906885d3eb068d20ce5800cb07014f
https://zenodo.org/record/161766
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10
Prognosis of aphasia in stroke patients early after iv thrombolysis
Autor: Fabienne Perren, Eufrozina Selariu, Kasim Abul-Kasim, Christine Kremer, Johan Kappelin
Publikováno v: Clinical Neurology and Neurosurgery, Vol. 115, No 3 (2013) pp. 289-292
Clinical Neurology and Neurosurgery; 115(3), pp 289-292 (2013)
OBJECTIVE: Stroke patients with aphasia have a high long-term morbidity. Intravenous rt-PA (iv) thrombolysis is given more deliberately to these patients. Early outcome data is lacking. Aim of this study was to determine early benefit from rt-PA in p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c5abb5a7356dc8599ee2b32e3290fa
https://archive-ouverte.unige.ch/unige:90325
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