Zobrazeno 1 - 10
of 1 286
pro vyhledávání: '"Brain Bank"'
Autor:
Kunie Ando, Marième Ndjim, Sabrina Turbant, Gaëlle Fontaine, Gustavo Pregoni, Luce Dauphinot, Zehra Yilmaz, Valérie Suain, Salwa Mansour, Michèle Authelet, Robert De Dekker, Karelle Leroy, Benoît Delatour, Brain Bank NeuroCEB Neuropathology Network, Charles Duyckaerts, Marie-Claude Potier, Jean-Pierre Brion
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-15 (2020)
Abstract Synaptojanin 1 (SYNJ1) is a brain-enriched lipid phosphatase critically involved in autophagosomal/endosomal trafficking, synaptic vesicle recycling and metabolism of phosphoinositides. Previous studies suggest that SYNJ1 polymorphisms have
Externí odkaz:
https://doaj.org/article/0a052a9fe57e48cdaf033a75854e03be
Autor:
Cristina Nuñez-Diaz, Emelie Andersson, Nina Schultz, Dovilė Pocevičiūtė, Oskar Hansson, The Netherlands Brain Bank, K Peter R. Nilsson, Malin Wennström
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Amyloid beta (Aβ) deposits and hyperphosphorylated tau (p-tau) accumulation have been identified in the retina of Alzheimer’s disease (AD) patients and transgenic AD mice. Previous studies have shown that retinal microglia engu
Externí odkaz:
https://doaj.org/article/27397dde590844f6a269713b5b3e9bdf
Autor:
Narimène Asbelaoui, Charly Abi-Ghanem, Géraldine Schlecht-Louf, Hania Oukil, Cindy Degerny, The Netherlands Brain Bank, Michael Schumacher, Abdel Mouman Ghoumari
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-25 (2024)
Abstract In men, reduced levels of testosterone are associated with the prevalence and progression of multiple sclerosis (MS), a chronic and disabling demyelinating disorder. Testosterone has been shown to promote myelin repair. Here, we demonstrate
Externí odkaz:
https://doaj.org/article/31f51b5ad97d44a495a82252831844e3
Autor:
Narimene Asbelaoui, Charly Abi–Ghanem, Geraldine Schlecht–Louf, Hania Oukil, Cindy Degerny, The Netherlands Brain Bank, Michael Schumacher, Abdel Mouman Ghoumarir
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/33084b3121354bb09637a0a8b509d26b
Autor:
Lucia AA Giannini, Merel O Mol, Ana Rajicic, Renee van Buuren, Lana Sarkar, Sanaz Arezoumandan, Daniel T Ohm, David J Irwin, Annemieke JM Rozemuller, Netherlands Brain Bank, John C van Swieten, Harro Seelaar
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-20 (2023)
Abstract Early pathological features of frontotemporal lobar degeneration (FTLD) due to MAPT pathogenic variants (FTLD-MAPT) are understudied, since early-stage tissue is rarely available. Here, we report unique pathological data from three presympto
Externí odkaz:
https://doaj.org/article/233371915a9f40739440fe3dd0d35b5a
Akademický článek
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Autor:
Luigi Fiondella, Priya Gami-Patel, Christian A. Blok, Annemieke J. M. Rozemuller, Jeroen J. M. Hoozemans, The Netherlands Brain Bank, Yolande A. L. Pijnenburg, Marta Scarioni, Anke A. Dijkstra
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-9 (2023)
Abstract Movement disorders (MD) have been linked to degeneration of the substantia nigra (SN) in Parkinson’s disease and include bradykinesia, rigidity, and tremor. They are also present in frontotemporal dementia (FTD), where MD have been linked
Externí odkaz:
https://doaj.org/article/bab65ac4d8ab44aa8bf3bf7b7f3a9496
Autor:
Cristina Nuñez-Diaz, Dovilė Pocevičiūtė, Nina Schultz, The Netherlands Brain Bank, Charlotte Welinder, Karl Swärd, Malin Wennström
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-11 (2023)
Abstract The islet amyloid polypeptide (IAPP), a pancreas-produced peptide, has beneficial functions in its monomeric form. However, IAPP aggregates, related to type 2 diabetes mellitus (T2DM), are toxic not only for the pancreas, but also for the br
Externí odkaz:
https://doaj.org/article/237474e1021e46ca980562fee8c36642
Autor:
Merel O. Mol, Suzanne S. M. Miedema, Shamiram Melhem, Ka Wan Li, Frank Koopmans, Harro Seelaar, Kurt Gottmann, Volkmar Lessmann, Netherlands Brain Bank, August B. Smit, John C. van Swieten, Jeroen G. J. van Rooij
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract Semantic dementia (SD) is a clinical subtype of frontotemporal dementia consistent with the neuropathological diagnosis frontotemporal lobar degeneration (FTLD) TDP type C, with characteristic round TDP-43 protein inclusions in the dentate g
Externí odkaz:
https://doaj.org/article/8c2d7e6c8ed449b1816eb6adb95fcab9
Autor:
Malin Wennström, Nina Schultz, Paula Mille Gallardo, The Netherlands Brain Bank, Geidy E. Serrano, Thomas G. Beach, Suchira Bose, Oskar Hansson
Publikováno v:
Cells, Vol 13, Iss 4, p 331 (2024)
The levels of p-tau217 and p-tau231 in cerebrospinal fluid (CSF) are associated with early amyloid beta (Aß) changes in the brain, while the CSF levels of p-tau205 are foremost related to tau pathology in the later stages of the disease. To investig
Externí odkaz:
https://doaj.org/article/5d38e2a219bc48b9afc1b06ad95db8b7