Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Brain / drug effects"'
Autor:
Kuhns, Lauren, Kroon, Emese, Lesscher, Heidi, Mies, Gabry, Cousijn, Janna, AISS Behaviour Neuroscience
Publikováno v:
Translational Psychiatry, 12(1):345. Nature Publishing Group
Translational Psychiatry, 12(1), 1. Nature Publishing Group
Translational Psychiatry, 12(1), 1. Nature Publishing Group
Adolescence is an important developmental period associated with increased risk for excessive alcohol use, but also high rates of recovery from alcohol use-related problems, suggesting potential resilience to long-term effects compared to adults. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd8e6be20d95f4fd4d99bba8221712b
https://pure.eur.nl/en/publications/e3293f32-174e-4c40-9cbe-b3cdcdf965f3
https://pure.eur.nl/en/publications/e3293f32-174e-4c40-9cbe-b3cdcdf965f3
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports, Vol. 11, No 1 (2021) P. 18137
Scientific Reports
Scientific Reports, Vol. 11, No 1 (2021) P. 18137
Scientific Reports
Despite Paraquat (PQ) being banned in several countries, it is still one of the most commonly used herbicides in agriculture. This compound is known to induce damaging effects on human and animal brain cells by generating Reactive Oxygen Species (ROS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f726193cd36deafe615910a48ce44729
https://doaj.org/article/084e55285876488aafdac7ec4a55a5eb
https://doaj.org/article/084e55285876488aafdac7ec4a55a5eb
Autor:
Gabriel Servilha-Menezes, Rui M.P. da Silva-Júnior, Melita Salkovic-Petrisic, Suélen Santos Alves, Jan Homolak, Norberto Garcia-Cairasco
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Almost 115 years ago, Alois Alzheimer described Alzheimer’s disease (AD) for the first time. Since then, many hypotheses have been proposed. However, AD remains a severe health public problem. The current medical approaches for AD are limited to sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9c906714bf33029469a2037701a83a
https://doi.org/10.3233/jad-210234
https://doi.org/10.3233/jad-210234
Publikováno v:
Anesthesia and Analgesia, 130(5), 1211-1221. LIPPINCOTT WILLIAMS & WILKINS
Anesthesia and Analgesia
Anesthesia and Analgesia
BACKGROUND: Brain monitors tracking quantitative brain activities from electroencephalogram (EEG) to predict hypnotic levels have been proposed as a labor-saving alternative to behavioral assessments. Expensive clinical trials are required to validat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0b635802c891e81444833e30597a86
https://doi.org/10.1213/ane.0000000000004651
https://doi.org/10.1213/ane.0000000000004651
Autor:
Jacobus Gidion Louw, Alastair van Heerden, Leana Olivier, Tersius Lambrechts, Mandi Broodryk, Liska Bunge, Martlé Vosloo, Mark Tomlinson
Publikováno v:
JMIR Formative Research
JMIR Formative Research, Vol 5, Iss 7, p e20658 (2021)
Louw, J G, van Heerden, A, Olivier, L, Lambrechts, T, Broodryk, M, Bunge, L, Vosloo, M & Tomlinson, M 2021, ' Executive Function After Prenatal Alcohol Exposure in Children in a South African Population: Cross-sectional Study ', JMIR formative research, vol. 5, no. 7, e20658 . https://doi.org/10.2196/20658
JMIR Formative Research, Vol 5, Iss 7, p e20658 (2021)
Louw, J G, van Heerden, A, Olivier, L, Lambrechts, T, Broodryk, M, Bunge, L, Vosloo, M & Tomlinson, M 2021, ' Executive Function After Prenatal Alcohol Exposure in Children in a South African Population: Cross-sectional Study ', JMIR formative research, vol. 5, no. 7, e20658 . https://doi.org/10.2196/20658
BackgroundAlcohol is a teratogen; its consumption during pregnancy can lead to negative birth outcomes, collectively referred to as fetal alcohol spectrum disorders. Neurodevelopmental delays in higher-order cognitive functions that affect developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::88a93dfc875c5afc06d764e3bb6ceab0
http://europepmc.org/articles/PMC8285745
http://europepmc.org/articles/PMC8285745
Autor:
Tom Hansen, Laszlo Vutskits, Fang Liu, Jurgen C. de Graaff, David O. Warner, Mary Ellen McCann, Lena S. Sun, James D. O’Leary, Karin Becke, Peter Szmuk, Nicola Groes Clausen, Andreas W. Loepke, Nicola Disma, Cynthia F. Salorio, Andrew Davidson, Ansgar M. Brambrink, Sulpicio G. Soriano
Publikováno v:
Paediatric Anaesthesia, 28(9), 758-763. Wiley-Blackwell Publishing Ltd
Paediatric Anaesthesia, Vol. 28, No 9 (2018) pp. 758-763
Disma, N, O'Leary, J D, Loepke, A W, Brambrink, A M, Becke, K, Clausen, N G, De Graaff, J C, Liu, F, Hansen, T G, McCann, M E, Salorio, C F, Soriano, S, Sun, L S, Szmuk, P, Warner, D O, Vutskits, L & Davidson, A J 2018, ' Anesthesia and the developing brain : A way forward for laboratory and clinical research ', Paediatric Anaesthesia, vol. 28, no. 9, pp. 758-763 . https://doi.org/10.1111/pan.13455
Paediatric Anaesthesia, Vol. 28, No 9 (2018) pp. 758-763
Disma, N, O'Leary, J D, Loepke, A W, Brambrink, A M, Becke, K, Clausen, N G, De Graaff, J C, Liu, F, Hansen, T G, McCann, M E, Salorio, C F, Soriano, S, Sun, L S, Szmuk, P, Warner, D O, Vutskits, L & Davidson, A J 2018, ' Anesthesia and the developing brain : A way forward for laboratory and clinical research ', Paediatric Anaesthesia, vol. 28, no. 9, pp. 758-763 . https://doi.org/10.1111/pan.13455
All commonly used general anesthetics have been shown to cause neurotoxicity in animal models, including nonhuman primates. Opinion, however, remains divided over how cumulative evidence from preclinical and human studies in this field should be inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afb306a3c2cbb0239679691cc4d3210
https://doi.org/10.1111/pan.13455
https://doi.org/10.1111/pan.13455
Autor:
M.R. Heiner-Fokkema, E. van Dam, F. J. van Spronsen, Raf Evers, Amj van Wegberg, Mch Janssen, M.C. de Vries, Jgm Burgerhof
Publikováno v:
Molecular Genetics and Metabolism, 133, 49-55
Molecular Genetics and Metabolism, 133, 1, pp. 49-55
Molecular Genetics and Metabolism, 133(1), 49-55. ACADEMIC PRESS INC ELSEVIER SCIENCE
Molecular Genetics and Metabolism, 133, 1, pp. 49-55
Molecular Genetics and Metabolism, 133(1), 49-55. ACADEMIC PRESS INC ELSEVIER SCIENCE
BACKGROUND: In patients with phenylketonuria, stability of blood phenylalanine and tyrosine concentrations might influence brain chemistry and therefore patient outcome. This study prospectively investigated the effects of tetrahydrobiopterin (BH4),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f717397510dcf86ca6197440b3604ef
http://hdl.handle.net/2066/233491
http://hdl.handle.net/2066/233491
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8767, p 8767 (2020)
Jensen, N J, Wodschow, H Z, Nilsson, M & Rungby, J 2020, ' Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases ', International Journal of Molecular Sciences, vol. 21, no. 22, 8767 . https://doi.org/10.3390/ijms21228767
International Journal of Molecular Sciences
Jensen, N J, Wodschow, H Z, Nilsson, M & Rungby, J 2020, ' Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases ', International Journal of Molecular Sciences, vol. 21, no. 22, 8767 . https://doi.org/10.3390/ijms21228767
International Journal of Molecular Sciences
Under normal physiological conditions the brain primarily utilizes glucose for ATP generation. However, in situations where glucose is sparse, e.g., during prolonged fasting, ketone bodies become an important energy source for the brain. The brain’
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5c473855e864b6d72fdac48583ef9c
https://www.mdpi.com/1422-0067/21/22/8767
https://www.mdpi.com/1422-0067/21/22/8767
Autor:
Gregers Wegener, Samia R. L. Joca, Ariandra G. Sartim, Cassiano F.A. Diniz, Aline Lulho Roncalho
Publikováno v:
Joca, S, Sartim, A, Roncalho, A, Diniz, C & Wegener, G 2019, ' Nitric oxide signalling and antidepressant action revisited ', Cell and Tissue Research, vol. 377, no. 1, pp. 45-58 . https://doi.org/10.1007/s00441-018-02987-4
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Cell and Tissue Research
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Cell and Tissue Research
Studies about the pathogenesis of mood disorders have consistently shownthat multiple factors, including genetic and environmental, play a crucial roleon their development and neurobiology. Multiple pathological theories havebeen proposed, of which s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe16e88a7cab374f9bfc128399ac3c9
https://doi.org/10.1007/s00441-018-02987-4
https://doi.org/10.1007/s00441-018-02987-4
Autor:
Jinglu Ai, R. L. Macdonald, Mervyn D.I. Vergouwen, Shakira Brathwaite, H Ni, Joost C. M. Meijers, H Wan, Yiming Wang, Elly M. Hol
Publikováno v:
Journal of Thrombosis and Haemostasis
Journal of Thrombosis and Haemostasis, 16, 1413-1422. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 16(7), 1413. Wiley-Blackwell
Journal of thrombosis and haemostasis, 16(7), 1413-1422. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 16, 1413-1422. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 16(7), 1413. Wiley-Blackwell
Journal of thrombosis and haemostasis, 16(7), 1413-1422. Wiley-Blackwell
Essentials von Willebrand Factor (VWF) and ADAMTS13 may affect early injury after subarachnoid hemorrhage (SAH). Early brain injury was assessed in VWF−/−, ADAMTS13−/− and recombinant (r) ADAMTS13 treated mice. VWF−/− and rADAMTS13 treate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b5717ba674e50c8f0ea29e47800996
https://doi.org/10.1111/jth.14136
https://doi.org/10.1111/jth.14136