Unraveling Brain Microcircuits, Dendritic Spines, and Synaptic Processing Using Multiple Complementary Approaches

Autor: Alberto A. Rasia-Filho

Publikováno v: Frontiers in Physiology, Vol 13 (2022)

Externí odkaz: https://doaj.org/article/8eb9977b5deb4cd9b30460af67e6c13b

TNF-α-sensitive brain pericytes activate microglia by releasing IL-6 through cooperation between IκB-NFκB and JAK-STAT3 pathways

Autor: Izzettin Hatip-Al-Khatib, Funda F. Bölükbaşı Hatip, Junichi Matsumoto, Fuyuko Takata, Takashi Machida, Yasufumi Kataoka, Shinya Dohgu, Atsushi Yamauchi

Publikováno v: Brain Research. 1692:34-44

Interleukin (IL)-6 is an important mediator of neurovascular dysfunction, neurodegeneration and/or neuroinflammation. We previously reported that brain pericytes released higher levels of IL-6 than did glial cells (astrocytes and microglia) in respon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706aba2f546c7b20734ef8cf336638f0
https://doi.org/10.1016/j.brainres.2018.04.023

Robust Control of a Brain-Persisting Parasite through MHC I Presentation by Infected Neurons

Autor: Anna Salvioni, Sophie Blanié, Virginie Vasseur, Nicolas Blanchard, Roland S. Liblau, Marcy Belloy, Ellen A. Robey, Elsa Suberbielle, Emilie Bassot, Vincent Cantaloube-Ferrieu, Aurore Lebourg

Publikováno v: Cell Reports
Cell Reports, 2019, 27 (11), pp.3254-3268.e8. ⟨10.1016/j.celrep.2019.05.051⟩
Cell Reports, Elsevier Inc, 2019, 27 (11), pp.3254-3268.e8. ⟨10.1016/j.celrep.2019.05.051⟩
Cell reports, vol 27, iss 11
Cell Rep
Cell Reports, Vol 27, Iss 11, Pp 3254-3268.e8 (2019)

Summary: Control of CNS pathogens by CD8 T cells is key to avoid fatal neuroinflammation. Yet, the modalities of MHC I presentation in the brain are poorly understood. Here, we analyze the antigen presentation mechanisms underlying CD8 T cell-mediate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b986ea5219ec9e06ea88a6de4a737a1c
https://hal.science/hal-02374306/document

Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity

Autor: Wolfgang Wurst, Ingrid Wagner, Thomas Misgeld, Rosa Maria Karl, Ralf Kühn, Jennifer Wettmarshausen, Nicolas Snaidero, Stefan F. Lichtenthaler, Laura Trovò, Stephan A. Müller, Fabiana Perocchi, Doron Merkler, Caroline Fecher, Jana Hartmann, Arthur Konnerth, Sylvia Heink, Thomas Korn, Oskar Ortiz

Publikováno v: Nature Neuroscience
Nature reviews / Neuroscience 22(10), 1731-1742 (2019). doi:10.1038/s41593-019-0479-z
Nature Neuroscience, Vol. 22, No 10 (2019) pp. 1731-1742

Mitochondria vary in morphology and function in different tissues; however, little is known about their molecular diversity among cell types. Here we engineered MitoTag mice, which express a Cre recombinase-dependent green fluorescent protein targete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c650d2db0b8796ebba9490815ff77185
https://pubmed.ncbi.nlm.nih.gov/31554939

Estudo sobre os neurônios de von Economo do pré-cúneo humano

Autor: Fuentealba Villarroel, Francisco Javier

Publikováno v: Biblioteca Digital de Teses e Dissertações da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS

O pré-cúneo (PC, área de Brodmann 7m) é uma estrutura localizada na porção póstero-medial do córtex parietal, de maior volume comparado com os primatas não humanos, ao qual são atribuídas funções sensório-motoras, cognitivas e visuais.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::c421475ba263357ad5e21e3e143d99c4