Potent efficacy signals from systemically administered oncolytic herpes simplex virus (HSV1716) in hepatocellular carcinoma xenograft models

Autor: Braidwood L, Learmonth K, Graham A, Conner J

Publikováno v: Journal of Hepatocellular Carcinoma, Vol 2014, Iss Issue 1, Pp 149-161 (2014)

Lynne Braidwood, Kirsty Learmonth, Alex Graham, Joe Conner Virttu Biologics Ltd, Department of Neurology, Southern General Hospital, Glasgow, UK Abstract: Oncolytic herpes simplex virus (HSV1716), lacking the neurovirulence factor ICP34.5, has highly

Externí odkaz: https://doaj.org/article/bd9f20b497cc499d999381183c08d2bd

A strategy for systemic delivery of the oncolytic herpes virus HSV1716: redirected tropism by antibody-binding sites incorporated on the virion surface as a glycoprotein D fusion protein.

Autor: Conner, J¹ jconner@crusadelabs.co.uk, Braidwood, L¹, Brown, S M¹

Publikováno v: Gene Therapy. Dec2008, Vol. 15 Issue 24, p1579-1592. 14p. 1 Color Photograph, 1 Black and White Photograph, 1 Diagram, 3 Charts, 2 Graphs.

Calcium Release Deficiency Syndrome (CRDS): Rethinking "Atypical" Catecholaminergic Polymorphic Ventricular Tachycardia.

Autor: Porretta, Alessandra P.^1,2 (AUTHOR) alessandra-pia.porretta@chuv.ch, Pruvot, Etienne¹ (AUTHOR), Bhuiyan, Zahurul A.³ (AUTHOR)

Publikováno v: Cardiogenetics. Dec2024, Vol. 14 Issue 4, p211-220. 10p.

Extensive recombination challenges the utility of Sugarcane mosaic virus phylogeny and strain typing.

Autor: Braidwood L; University of Cambridge, Department of Plant Sciences, Cambridge, CB2 3EA, United Kingdom. braidwoodluke@gmail.com., Müller SY; University of Cambridge, Department of Plant Sciences, Cambridge, CB2 3EA, United Kingdom., Baulcombe D; University of Cambridge, Department of Plant Sciences, Cambridge, CB2 3EA, United Kingdom.

Publikováno v: Scientific reports [Sci Rep] 2019 Dec 27; Vol. 9 (1), pp. 20067. Date of Electronic Publication: 2019 Dec 27.

Please stand by: how oncolytic viruses impact bystander cells.

Autor: Sprague L; The Ohio State University College of Medicine, Biomedical Sciences Graduate Program, Columbus, 43201 OH, USA.; The Ohio State University College of Medicine, Biomedical Sciences Graduate Program, Columbus, 43201 OH, USA., Braidwood L; Virttu Biologics, BioCity, Scotland, UK.; Virttu Biologics, BioCity, Scotland, UK., Conner J; Virttu Biologics, BioCity, Scotland, UK.; Virttu Biologics, BioCity, Scotland, UK., Cassady KA; Nationwide Children's Hospital, Division of Infectious Diseases, Columbus, 43205 OH, USA.; Nationwide Children's Hospital, Division of Hematology/Oncology/BMT & Center for Childhood Cancer & Blood Diseases, Columbus, 43205 OH, USA.; Nationwide Children's Hospital, Division of Infectious Diseases, Columbus, 43205 OH, USA.; Nationwide Children's Hospital, Division of Hematology/Oncology/BMT & Center for Childhood Cancer & Blood Diseases, Columbus, 43205 OH, USA., Benencia F; Ohio University Russ College of Engineering & Technology, Biomedical Engineering, Athens, 45701 OH, USA.; Ohio University Russ College of Engineering & Technology, Biomedical Engineering, Athens, 45701 OH, USA., Cripe TP; The Ohio State University College of Medicine, Biomedical Sciences Graduate Program, Columbus, 43201 OH, USA.; Nationwide Children's Hospital, Division of Hematology/Oncology/BMT & Center for Childhood Cancer & Blood Diseases, Columbus, 43205 OH, USA.; The Ohio State University College of Medicine, Biomedical Sciences Graduate Program, Columbus, 43201 OH, USA.; Nationwide Children's Hospital, Division of Hematology/Oncology/BMT & Center for Childhood Cancer & Blood Diseases, Columbus, 43205 OH, USA.

Publikováno v: Future virology [Future Virol] 2018 Sep; Vol. 13 (9), pp. 671-680. Date of Electronic Publication: 2018 Aug 08.