Safety outcomes when switching between biosimilars and reference biologics: A systematic review and meta-analysis.

Autor: Herndon TM; Office of Therapeutic Biologics and Biosimilars, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America., Ausin C; Office of Therapeutic Biologics and Biosimilars, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America., Brahme NN; Office of Therapeutic Biologics and Biosimilars, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America., Schrieber SJ; Office of Therapeutic Biologics and Biosimilars, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America., Luo M; Office of Therapeutic Biologics and Biosimilars, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America., Andrada FC; Office of Therapeutic Biologics and Biosimilars, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America., Kim C; Office of Therapeutic Biologics and Biosimilars, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America., Sun W; Division of Biometrics VIII, Office of Biostatistics, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America., Zhou L; Division of Biometrics VIII, Office of Biostatistics, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America., Grosser S; Division of Biometrics VIII, Office of Biostatistics, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America., Yim S; Office of Therapeutic Biologics and Biosimilars, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America., Ricci MS; Office of Therapeutic Biologics and Biosimilars, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America.

Publikováno v: PloS one [PLoS One] 2023 Oct 03; Vol. 18 (10), pp. e0292231. Date of Electronic Publication: 2023 Oct 03 (Print Publication: 2023).

Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation.

Autor: Huet-Calderwood C; Department of Pharmacology, Yale University, New Haven, CT 06520, USA., Brahme NN; Department of Cell Biology, Yale University, New Haven, CT 06520, USA., Kumar N; Department of Cell Biology, Yale University, New Haven, CT 06520, USA., Stiegler AL; Department of Pharmacology, Yale University, New Haven, CT 06520, USA., Raghavan S; Department of Pharmacology, Yale University, New Haven, CT 06520, USA Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, Karnataka 560065, India., Boggon TJ; Department of Pharmacology, Yale University, New Haven, CT 06520, USA., Calderwood DA; Department of Pharmacology, Yale University, New Haven, CT 06520, USA Department of Cell Biology, Yale University, New Haven, CT 06520, USA david.calderwood@yale.edu.

Publikováno v: Journal of cell science [J Cell Sci] 2014 Oct 01; Vol. 127 (Pt 19), pp. 4308-21. Date of Electronic Publication: 2014 Aug 01.

Kindlin binds migfilin tandem LIM domains and regulates migfilin focal adhesion localization and recruitment dynamics.

Autor: Brahme NN; From the Departments of Cell Biology and., Harburger DS, Kemp-O'Brien K, Stewart R, Raghavan S, Parsons M, Calderwood DA

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2013 Dec 06; Vol. 288 (49), pp. 35604-16. Date of Electronic Publication: 2013 Oct 28.

Cell adhesion: a FERM grasp of the tail sorts out integrins.

Autor: Brahme NN; Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520-8066, USA., Calderwood DA

Publikováno v: Current biology : CB [Curr Biol] 2012 Sep 11; Vol. 22 (17), pp. R692-4.

A conserved lipid-binding loop in the kindlin FERM F1 domain is required for kindlin-mediated αIIbβ3 integrin coactivation.

Autor: Bouaouina M; Department of Pharmacology and Cell Biology and Interdepartmental Program in Vascular Biology and Therapeutics, Yale University School of Medicine, New Haven, Connecticut 06520, USA., Goult BT, Huet-Calderwood C, Bate N, Brahme NN, Barsukov IL, Critchley DR, Calderwood DA

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2012 Mar 02; Vol. 287 (10), pp. 6979-90. Date of Electronic Publication: 2012 Jan 10.