Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Brahmananda R. Chitteti"'
Autor:
Ying-Hua Cheng, Robyn K. Fuchs, Haley McGough, David J. Olivos, Pierre P. Eleniste, Richard Adam Hooker, Marta Alvarez, Edward F. Srour, Mark C. Horowitz, Christopher Yim, Wendy A. Ciovacco, Monique Bethel, Angela Bruzzaniti, Brahmananda R. Chitteti, Melissa A. Kacena
Publikováno v:
Journal of Cellular Biochemistry. 118:2231-2240
The Lnk adapter protein negatively regulates the signaling of thrombopoietin (TPO), the main megakaryocyte (MK) growth factor. Lnk-deficient (-/-) mice have increased TPO signaling and increased MK number. Interestingly, several mouse models exist in
Autor:
Brahmananda R. Chitteti, Edward F. Srour, Angela Bruzzaniti, Amanda F. Taylor, Melissa A. Kacena, Monique Bethel, Mark C. Horowitz, Ying Hua Cheng, Calvin L. T. Barnes
Publikováno v:
Journal of Cellular Physiology. 230:2142-2151
Emerging data suggest that megakaryocytes (MKs) play a significant role in skeletal homeostasis. Indeed, osteosclerosis observed in several MK-related disorders may be a result of increased numbers of MKs. In support of this idea, we have previously
Autor:
Kelly S. Schweitzer, Darwin J. Prockop, Ru Yi, Hal E. Broxmeyer, Jie Xie, Dmitry O. Traktuev, Todd G. Cook, Brahmananda R. Chitteti, Xuan Ou, Matthew J. Justice, Dongni Feng, Keith L. March, Edward F. Srour, Daria Barwinska, Mary Van Demark, Irina Petrache
Publikováno v:
Stem Cells. 33:468-478
Objective: Bone marrow-derived hematopoietic stem and progenitor cells (HSC/HPC) are critical to homeostasis and tissue repair. The aims of this study were to delineate the myelotoxicity of cigarette smoking (CS) in a murine model, to explore human a
Autor:
Fredrick M. Pavalko, Melissa A. Kacena, Joseph P. Bidwell, Lindsey D. Mayo, Mark C. Horowitz, Brahmananda R. Chitteti, Rita Gerard-O'Riley, Drew A. Streicher, Edward F. Srour, Ying Hua Cheng, David L. Waning
Publikováno v:
Journal of Cellular Physiology. 230:578-586
Recent studies suggest that megakaryocytes (MKs) may play a significant role in skeletal homeostasis, as evident by the occurrence of osteosclerosis in multiple MK related diseases (Lennert et al., 1975; Thiele et al., 1999; Chagraoui et al., 2006).
Autor:
David J, Olivos, Marta, Alvarez, Ying-Hua, Cheng, Richard Adam, Hooker, Wendy A, Ciovacco, Monique, Bethel, Haley, McGough, Christopher, Yim, Brahmananda R, Chitteti, Pierre P, Eleniste, Mark C, Horowitz, Edward F, Srour, Angela, Bruzzaniti, Robyn K, Fuchs, Melissa A, Kacena
Publikováno v:
Journal of cellular biochemistry. 118(8)
The Lnk adapter protein negatively regulates the signaling of thrombopoietin (TPO), the main megakaryocyte (MK) growth factor. Lnk-deficient (−/−) mice have increased TPO signaling and increased MK number. Interestingly, several mouse models exis
Publikováno v:
Stem cells (Dayton, Ohio). 36(1)
Although mesenchymal stromal cells (MSCs) have significant potential in cell-based therapies, little is known about the factors that regulate their functions. While exploring regulatory molecules potentially involved in MSC activities, we found that
Publikováno v:
Current Opinion in Hematology. 20:273-280
Purpose of review Many surface antigens have been previously used to identify hematopoietic stem cells or cellular elements of the hematopoietic niche. However, to date, not a single surface marker has been identified as a common marker expressed on
Autor:
Tomas E. Meijome, Fredrick M. Pavalko, Brahmananda R. Chitteti, Khanh Nguyen, Lindsey D. Mayo, Edward F. Srour, Artur Plett, Hui Lin Chua, Christie M. Orschell, Melissa A. Kacena, R. Adam Hooker, Angela Bruzzaniti, Rita Gerard-O'Riley, Ying Hua Cheng, David L. Waning
Publikováno v:
Journal of Bone and Mineral Research. 28:1434-1445
Preclinical and clinical evidence from megakaryocyte (MK)-related diseases suggests that MKs play a significant role in maintaining bone homeostasis. Findings from our laboratories reveal that MKs significantly increase osteoblast (OB) number through
Autor:
Jonathan Hoggatt, Giao Hangoc, Steven Messina-Graham, Sara L. Rohrabaugh, Sherif S. Farag, Brahmananda R. Chitteti, Louis M. Pelus, Heather O'Leary, Xuan Ou, Jennifer M. Speth, Hal E. Broxmeyer, Timothy B. Campbell, Scott Cooper, Charlie Mantel, Edward F. Srour
Publikováno v:
Nature Medicine. 18:1786-1796
Enhancement of hematopoietic recovery after radiation, chemotherapy, or hematopoietic stem cell (HSC) transplantation is clinically relevant. Dipeptidylpeptidase (DPP4) cleaves a wide variety of substrates, including the chemokine stromal cell-derive
Autor:
Dongjun Lee, Charles P. Lin, Kalle Sipilä, Jyrki Heino, Tiffany A. Tate, Raphaël Turcotte, Youmna Kfoury, Kevin A. Goncalves, Joel A. Spencer, Francois Mercier, Brahmananda R. Chitteti, Ninib Baryawno, Noriaki Ono, Toshihiro Shioda, Cristina Lo Celso, Masatake Osawa, Edward F. Srour, David T. Scadden, Jonathan Hoggatt, Ani Papazian, Guo-fu Hu, Peter V. Kharchenko, Jacqueline Bachand, Lev Silberstein, Nicolas Severe, Stephen L. Nutt
Physiological stem cell function is regulated by secreted factors produced by niche cells. In this study, we describe an unbiased approach based on the differential single-cell gene expression analysis of mesenchymal osteolineage cells close to, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9afb79d90b5218e62fd2e00862fd5b6
https://europepmc.org/articles/PMC5402355/
https://europepmc.org/articles/PMC5402355/