Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Brahma V. Kumar"'
Autor:
Michelle Miron, Wenzhao Meng, Aaron M. Rosenfeld, Shirit Dvorkin, Maya Meimei Li Poon, Nora Lam, Brahma V. Kumar, Yoram Louzoun, Eline T. Luning Prak, Donna L. Farber
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)
Abstract Background Immune-mediated protection is mediated by T cells expressing pathogen-specific T cell antigen receptors (TCR) that are maintained at diverse sites of infection as tissue-resident memory T cells (TRM) or that disseminate as circula
Externí odkaz:
https://doaj.org/article/c9735e3dd8794a808679dc6e6b7b0c8f
Autor:
Brahma V. Kumar, Wenji Ma, Michelle Miron, Tomer Granot, Rebecca S. Guyer, Dustin J. Carpenter, Takashi Senda, Xiaoyun Sun, Siu-Hong Ho, Harvey Lerner, Amy L. Friedman, Yufeng Shen, Donna L. Farber
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2921-2934 (2017)
Tissue-resident memory T cells (TRMs) in mice mediate optimal protective immunity to infection and vaccination, while in humans, the existence and properties of TRMs remain unclear. Here, we use a unique human tissue resource to determine whether hum
Externí odkaz:
https://doaj.org/article/f3e9780754764601b97c47d562f49b9a
Autor:
Shirit Dvorkin, Maya Meimei Li Poon, Yoram Louzoun, Nora Lam, Brahma V Kumar, Eline T. Luning Prak, Donna L. Farber, Michelle Miron, Wenzhao Meng, Aaron M. Rosenfeld
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)
Genome Medicine
Genome Medicine
BackgroundImmune-mediated protection is mediated by T cells expressing pathogen-specific T cell antigen receptors (TCR) that are maintained at diverse sites of infection as tissue-resident memory T cells (TRM) or that disseminate as circulating effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c81d2eea554e3d5ca673edab42bae8
Autor:
Yufeng Shen, Uri Hershberg, Wenzhao Meng, Aaron M. Rosenfeld, Takashi Senda, Bochao Zhang, Dora Chen, Dustin J. Carpenter, Adeeb Rahman, Eline T. Luning Prak, Amy L. Friedman, Tomer Granot, Brahma V. Kumar, Michelle Miron, Harvey Lerner, Donna L. Farber
Publikováno v:
The Journal of Immunology. 201:2132-2140
Translating studies on T cell function and modulation from mouse models to humans requires extrapolating in vivo results on mouse T cell responses in lymphoid organs (spleen and lymph nodes [LN]) to human peripheral blood T cells. However, our unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d12eac96215337f51e0d1a6e5996a279
https://doi.org/10.4049/jimmunol.1800716
https://doi.org/10.4049/jimmunol.1800716
Publikováno v:
Immunity. 48:202-213
Throughout life, T cells coordinate multiple aspects of adaptive immunity, including responses to pathogens, allergens, and tumors. In mouse models, the role of T cells is studied in the context of a specific type of pathogen, antigen, or disease con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d589e80f9f9429e4a9df8f06acce195b
https://doi.org/10.1016/j.immuni.2018.01.007
https://doi.org/10.1016/j.immuni.2018.01.007
Autor:
Rebecca S. Guyer, Dustin Carpener, Takashi Senda, Yufeng Shen, Amy L. Friedman, Tomer Granot, Michelle Miron, Harvey Lerner, Brahma V. Kumar, Xiaoyun Sun, Donna L. Farber, Siu-hong Ho, Wenji Ma
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2921-2934 (2017)
Tissue-resident memory T cells (TRMs) in mice mediate optimal protective immunity to infection and vaccination, while in humans, the existence and properties of TRMs remain unclear. Here, we use a unique human tissue resource to determine whether hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60c7c7197dc03e1ec769021fcf798764
http://www.sciencedirect.com/science/article/pii/S2211124717312202
http://www.sciencedirect.com/science/article/pii/S2211124717312202
Autor:
Attila Bacsi, Balazs Hegedus, Tünde Fekete, Zsofia Foldvari, Arpad Lanyi, Brahma V. Kumar, Éva Rajnavölgyi, Kitti Pazmandi, Tamás Garay, Gábor Koncz, Attila Szabo
Publikováno v:
Cellular Signalling. 28:335-347
Background BRAF-mutant melanoma is characterized by aggressive metastatic potential and therapeutic resistance. The innate immune receptor RIG-I has emerged as a potential target in melanoma therapies but the contributing pathways involved in anti-ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::addfc2eaef1c1524a2b7ae7b3bcecaee
https://doi.org/10.1016/j.cellsig.2016.01.012
https://doi.org/10.1016/j.cellsig.2016.01.012
Autor:
Radomir Kratchmarov, Michelle Miron, Takashi Senda, Harvey Lerner, Donna L. Farber, Amy L. Friedman, Steven L. Reiner, Dustin J. Carpenter, Brahma V. Kumar
Publikováno v:
JCI Insight. 3
Tissue-resident memory T cells (TRMs) accelerate pathogen clearance through rapid and enhanced functional responses in situ. TRMs are prevalent in diverse anatomic sites throughout the human lifespan, yet their phenotypic and functional diversity has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5707a3b93f382956e8726d14ac672d9
https://doi.org/10.1172/jci.insight.123568
https://doi.org/10.1172/jci.insight.123568
Autor:
Michelle, Miron, Brahma V, Kumar, Wenzhao, Meng, Tomer, Granot, Dustin J, Carpenter, Takashi, Senda, Dora, Chen, Aaron M, Rosenfeld, Bochao, Zhang, Harvey, Lerner, Amy L, Friedman, Uri, Hershberg, Yufeng, Shen, Adeeb, Rahman, Eline T, Luning Prak, Donna L, Farber
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 201(7)
Translating studies on T cell function and modulation from mouse models to humans requires extrapolating in vivo results on mouse T cell responses in lymphoid organs (spleen and lymph nodes) to human peripheral blood T cells. However, our understandi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c83f3af49a16d38a8c448b573502666
https://pubmed.ncbi.nlm.nih.gov/30111633
https://pubmed.ncbi.nlm.nih.gov/30111633
Autor:
Harvey Lerner, Brahma V. Kumar, Thomas J. Connors, Dustin J. Carpenter, Nobuhide Matsuoka, Adam Griesemer, Donna L. Farber, Joseph J.C. Thome, Takashi Senda, Claire L. Gordon, Michelle Miron, Tomoaki Kato, Amy L. Friedman, Tomer Granot, Joshua Weiner
Organ donors are sources of physiologically healthy organs and tissues for life-saving transplantation, and have been recently used for human immunology studies which are typically confined to the sampling of peripheral blood. Donors comprise a diver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44512941920098cc755261b5d537bf0c
https://europepmc.org/articles/PMC5740015/
https://europepmc.org/articles/PMC5740015/