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pro vyhledávání: '"Brahma P. Sani"'
Autor:
Brahma P. Sani
Publikováno v:
Chemistry and Biology of Synthetic Retinoids ISBN: 9781351070638
Chemistry and Biology of Synthetic Retinoids
Chemistry and Biology of Synthetic Retinoids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6678ba82a46c546f6ac2324a292773d
https://doi.org/10.1201/9781351070638-15
https://doi.org/10.1201/9781351070638-15
Publikováno v:
Archives of Biochemistry and Biophysics. 343:234-242
To characterize the dimerization of retinoid receptors in solution, RAR alpha homodimers and RAR alpha-RXR alpha heterodimers, formed in the absence or the presence of a naturally occurring RA response element (betaRARE) under different ionic conditi
Publikováno v:
Biochemical and Biophysical Research Communications. 223:293-298
Retinyl methyl ether (RME) which prevents cancers of the rat mammary gland, binds to cellular retinol-binding protein and serum retinol-binding protein but not to cellular retinoic acid-binding protein or to the nuclear retinoid receptors, RARs/RXRs.
Autor:
Lee Mo, Muzaffar Alam, Levin Aa, Pratap Venepally, Zhestkov, E. Li, Brahma P. Sani, Andrew W. Norris, Kazmer S, Xiao-kun Zhang
Publikováno v:
Journal of Medicinal Chemistry. 38:2302-2310
We recently demonstrated in animal models that a new conformationally defined RA isomer (Vaezi et al. J. Med. Chem. 1994, 37, 4499-4507) was as effective as RA in the prevention of skin papillomas but was less toxic. In order to provide more details
Publikováno v:
Carcinogenesis. 16:2531-2534
The cellular transport, metabolism and biological activity of retinoids are mediated by their specific binding proteins and nuclear receptors. For an understanding of the mode of action of retinoids with potential cancer chemopreventive or other biol
Autor:
Donald L. Hill, Brahma P. Sani
Publikováno v:
ChemInform. 22
Publisher Summary The word retinoid is a general term that includes both the naturally occurring compounds with vitamin A activity and the synthetic analogs of retinol, with or without biological activity. The classic retinoid structure is generally
Autor:
Adam B. Keeton, Jason Whitt, Gregory S. Gorman, Bini Mathew, Lori Coward, Heather N. Tinsley, Gary A. Piazza, Robert C. Reynolds, Brahma P. Sani, Bernard D. Gary, Jose Thaiparambil, Yonghe Li, Yulia Maxuitenko, Judith V. Hobrath
Publikováno v:
Cancer prevention research (Philadelphia, Pa.). 2(6)
Nonsteroidal anti-inflammatory drugs such as sulindac have shown promising antineoplastic activity, although toxicity from cyclooxygenase (COX) inhibition and the suppression of prostaglandin synthesis limits their use for chemoprevention. Previous s
Autor:
Donald L. Hill, Brahma P. Sani
Publikováno v:
Drug Metabolism Reviews. 23:413-438
(1991). Metabolic Disposition and Development of New Chemopreventive Retinoids. Drug Metabolism Reviews: Vol. 23, No. 3-4, pp. 413-438.
Autor:
Leonard J. Schiff, Gang Liu, Tomas Mustelin, Danni L. Harris, Brahma P. Sani, Jun-ichi Fukushi, Zebin Xia, Mao Ye, Peter D. Hobbs, Sankari Arumugarajah, Marcia I. Dawson, Wan-Ru Chao, William B. Stallcup, Xiao-kun Zhang, Ying Su, Nahid Waleh, Lulu Farhana, Lutz Tautz, Young-Hoon Han, Joseph A. Fontana, Bhamik B. Patel, Mohammad Bhuiyan, Ling Jong
Apoptotic and antiproliferative activities of small heterodimer partner (SHP) nuclear receptor ligand (E)-4-[3'-(1-adamantyl)-4'-hydroxyphenyl]-3-chlorocinnamic acid (3-Cl-AHPC), which was derived from 6-[3'-(1-adamantyl)-4'-hydroxyphenyl]-2-naphthal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07933b22a5efeceee356dbb6c7bcb108
https://europepmc.org/articles/PMC2528874/
https://europepmc.org/articles/PMC2528874/
Autor:
Brahma P. Sani, Jerry L. Frye, James M. Riordan, Linda Simpson-Herren, Y. Fulmer Shealy, Donald L. Hill
Publikováno v:
Journal of medicinal chemistry. 46(10)
The design of analogues of 7,8-dihydroretinoic acid (7,8-dihydro-RA) was based on reported biological activities of this retinoid and its dihydro-TMMP(1) analogue and on structural hypotheses. 7-Oxa-7,8-dihydroretinoids (5, 6) were prepared by O-alky