Zobrazeno 1 - 10
of 598
pro vyhledávání: '"Brahm, J"'
Autor:
Ahmad, Raheel, Tyryshkin, Alexei M., Xie, Lingjun, Hansen, William A., Yachnin, Brahm J., Emge, Thomas J., Mashrai, Ashraf, Khare, Sagar D., Knapp, Spencer
Publikováno v:
In Journal of Inorganic Biochemistry July 2023 244
Autor:
Julia Koehler Leman, Sergey Lyskov, Steven M. Lewis, Jared Adolf-Bryfogle, Rebecca F. Alford, Kyle Barlow, Ziv Ben-Aharon, Daniel Farrell, Jason Fell, William A. Hansen, Ameya Harmalkar, Jeliazko Jeliazkov, Georg Kuenze, Justyna D. Krys, Ajasja Ljubetič, Amanda L. Loshbaugh, Jack Maguire, Rocco Moretti, Vikram Khipple Mulligan, Morgan L. Nance, Phuong T. Nguyen, Shane Ó Conchúir, Shourya S. Roy Burman, Rituparna Samanta, Shannon T. Smith, Frank Teets, Johanna K. S. Tiemann, Andrew Watkins, Hope Woods, Brahm J. Yachnin, Christopher D. Bahl, Chris Bailey-Kellogg, David Baker, Rhiju Das, Frank DiMaio, Sagar D. Khare, Tanja Kortemme, Jason W. Labonte, Kresten Lindorff-Larsen, Jens Meiler, William Schief, Ora Schueler-Furman, Justin B. Siegel, Amelie Stein, Vladimir Yarov-Yarovoy, Brian Kuhlman, Andrew Leaver-Fay, Dominik Gront, Jeffrey J. Gray, Richard Bonneau
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Computational methods are becoming an increasingly important part of biological research. Using the Rosetta framework as an example, the authors demonstrate how community-driven development of computational methods can be done in a reproducible and r
Externí odkaz:
https://doaj.org/article/7ccba8c202cd473d906c246ef7b2eb77
Autor:
Jacynthe L. Toulouse, Brahm J. Yachnin, Edward H. Ruediger, Daniel Deon, Marc Gagnon, Kévin Saint-Jacques, Maximilian C. C. J. C. Ebert, Delphine Forge, Dominic Bastien, Damien Y. Colin, Jean Jacques Vanden Eynde, Anne Marinier, Albert M. Berghuis, Joelle N. Pelletier
Publikováno v:
ACS Omega, Vol 4, Iss 6, Pp 10056-10069 (2019)
Externí odkaz:
https://doaj.org/article/b6882ec44dce4affaf57abba4a81cf46
Publikováno v:
In BBA - Proteins and Proteomics December 2016 1864(12):1641-1648
Akademický článek
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Autor:
Raheel Ahmad, Alexei M. Tyryshkin, Lingjun Xie, William A. Hansen, Brahm J. Yachnin, Thomas J. Emge, Ashraf Mashrai, Sagar D. Khare, Spencer Knapp
Publikováno v:
Journal of Inorganic Biochemistry. 244:112206
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d401d705c920cb4c824ea5b46407c1d
https://doi.org/10.1016/j.jinorgbio.2023.112206
https://doi.org/10.1016/j.jinorgbio.2023.112206
Publikováno v:
J Chem Inf Model
As non-"self" macromolecules, biotherapeutics can trigger an immune response that can reduce drug efficacy, require patients to be taken off therapy, or even cause life-threatening reactions. To enable the flexible and facile design of protein biothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c782b568342e5b384ee89a5369293138
https://doi.org/10.1021/acs.jcim.1c00056
https://doi.org/10.1021/acs.jcim.1c00056
Autor:
Brahm J. Yachnin, Sai Kiran Naineni, Mehdi Amiri, Jutta Steinberger, Jerry Pelletier, Sarah A.E. Aboushawareb, Stephen J Kiniry, Francis Robert, Regina Cencic, Pavel V. Baranov, Nahum Sonenberg, Jennifer Chu, Leo Shen, Rayelle Itoua Maïga
Publikováno v:
Nucleic Acids Research
Hippuristanol (Hipp) is a natural product that selectively inhibits protein synthesis by targeting eukaryotic initiation factor (eIF) 4A, a DEAD-box RNA helicase required for ribosome recruitment to mRNA templates. Hipp binds to the carboxyl-terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fdcf49ca66e056ff882d0364ea18d02
https://doi.org/10.1093/nar/gkaa662
https://doi.org/10.1093/nar/gkaa662
Autor:
Brahm J. Yachnin, Laura R. Azouz, Ralph E. White, Conceição A. S. A. Minetti, David P. Remeta, Victor M. Tan, Justin M. Drake, Sagar D. Khare
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Confining the activity of a designed protein to a specific microenvironment would have broad-ranging applications, such as enabling cell type-specific therapeutic action by enzymes while avoiding off-target effects. While many natural enzymes are syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0920c37310a6575d4da650a701305f02
https://doi.org/10.1073/pnas.2116097119
https://doi.org/10.1073/pnas.2116097119
Akademický článek
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