A new piperazine derivative: 1-(4-(3,5-di-tert-butyl-4-hydroxybenzyl) piperazin-1-yl)-2-methoxyethan-1-one with antioxidant and central activity.

Autor: Brito AF; Post Graduate Program in Biological Sciences, ICB, Federal University of Goiás, Campus Samambaia, Goiania, GO, 74001-970, Brazil., Braga PCCS; Faculty of Pharmacy, Laboratory of Medicinal Pharmaceutical Chemistry, Federal University of Goiás, Goiania, GO, Brazil., Moreira LKS; Post Graduate Program in Biological Sciences, ICB, Federal University of Goiás, Campus Samambaia, Goiania, GO, 74001-970, Brazil., Silva DM; Post Graduate Program in Biological Sciences, ICB, Federal University of Goiás, Campus Samambaia, Goiania, GO, 74001-970, Brazil., Silva DPB; Post Graduate Program in Biological Sciences, ICB, Federal University of Goiás, Campus Samambaia, Goiania, GO, 74001-970, Brazil., Sanz G; Chemistry Institute, Federal University of Goiás, Campus Samambaia, Goiania, GO, Brazil., Vaz BG; Chemistry Institute, Federal University of Goiás, Campus Samambaia, Goiania, GO, Brazil., de Carvalho FS; Chemistry Institute, Federal University of Goiás, Campus Samambaia, Goiania, GO, Brazil., Lião LM; Chemistry Institute, Federal University of Goiás, Campus Samambaia, Goiania, GO, Brazil., Silva RR; Laboratory of Biochemical and Molecular Pharmacology, Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Noël F; Laboratory of Biochemical and Molecular Pharmacology, Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Neri HFS; Post Graduate Program in Biological Sciences, ICB, Federal University of Goiás, Campus Samambaia, Goiania, GO, 74001-970, Brazil., Ghedini PC; Post Graduate Program in Biological Sciences, ICB, Federal University of Goiás, Campus Samambaia, Goiania, GO, 74001-970, Brazil., de Carvalho MF; Faculty of Pharmacy, Laboratory of Medicinal Pharmaceutical Chemistry, Federal University of Goiás, Goiania, GO, Brazil., de S Gil E; Faculty of Pharmacy, Laboratory of Medicinal Pharmaceutical Chemistry, Federal University of Goiás, Goiania, GO, Brazil., Costa EA; Department of Pharmacology, ICB, Federal University of Goiás, Campus Samambaia, 314, Goiania, GO, 74001-970, Brazil. xico@ufg.br., Menegatti R; Faculty of Pharmacy, Laboratory of Medicinal Pharmaceutical Chemistry, Federal University of Goiás, Goiania, GO, Brazil.

Publikováno v: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2018 Mar; Vol. 391 (3), pp. 255-269. Date of Electronic Publication: 2017 Dec 19.