Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Brady F, Cress"'
Autor:
Denish Piya, Nicholas Nolan, Madeline L Moore, Luis A Ramirez Hernandez, Brady F Cress, Ry Young, Adam P Arkin, Vivek K Mutalik
Publikováno v:
PLoS Biology, Vol 21, Iss 12, p e3002416 (2023)
Phages are one of the key ecological drivers of microbial community dynamics, function, and evolution. Despite their importance in bacterial ecology and evolutionary processes, phage genes are poorly characterized, hampering their usage in a variety
Externí odkaz:
https://doaj.org/article/be995ca2d1d543d08eae1523a7649a57
Autor:
Megan Kizer, Peiqin Li, Brady F. Cress, Lei Lin, Tom T. Jing, Xing Zhang, Ke Xia, Robert J. Linhardt, Xing Wang
Publikováno v:
ACS Omega, Vol 3, Iss 10, Pp 13667-13675 (2018)
Externí odkaz:
https://doaj.org/article/70d031b5d389477d8761c7a290d2d8bc
Autor:
Benjamin A. Adler, Tomas Hessler, Brady F. Cress, Arushi Lahiri, Vivek K. Mutalik, Rodolphe Barrangou, Jillian Banfield, Jennifer A. Doudna
Publikováno v:
Nature Microbiology. 7:1967-1979
CRISPR-Cas13 proteins are RNA-guided RNA nucleases that defend against incoming RNA and DNA phages by binding to complementary target phage transcripts followed by general, non-specific RNA degradation. Here we analysed the defensive capabilities of
Autor:
Gavin J Knott, Brady F Cress, Jun-Jie Liu, Brittney W Thornton, Rachel J Lew, Basem Al-Shayeb, Daniel J Rosenberg, Michal Hammel, Benjamin A Adler, Marco J Lobba, Michael Xu, Adam P Arkin, Christof Fellmann, Jennifer A Doudna
Publikováno v:
eLife, Vol 8 (2019)
CRISPR-Cas systems provide bacteria and archaea with programmable immunity against mobile genetic elements. Evolutionary pressure by CRISPR-Cas has driven bacteriophage to evolve small protein inhibitors, anti-CRISPRs (Acrs), that block Cas enzyme fu
Externí odkaz:
https://doaj.org/article/164dc30ebd294804bf4e661f484ab735
Autor:
Denish Piya, Nicholas Nolan, Madeline L. Moore, Luis A. Ramirez Hernandez, Brady F. Cress, Ry Young, Adam P. Arkin, Vivek K. Mutalik
Phages are one of the key ecological drivers of microbial community dynamics, function and evolution. Despite their importance in bacterial ecology and evolutionary processes, phage genes are poorly characterized, hampering their usage in a variety o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57a1ae4aa94bfc37ae412155b9f2eba5
https://doi.org/10.1101/2023.05.14.540688
https://doi.org/10.1101/2023.05.14.540688
Autor:
J. Andrew Jones, Victoria R. Vernacchio, Shannon M. Collins, Abhijit N. Shirke, Yu Xiu, Jacob A. Englaender, Brady F. Cress, Catherine C. McCutcheon, Robert J. Linhardt, Richard A. Gross, Mattheos A. G. Koffas
Publikováno v:
mBio, Vol 8, Iss 3 (2017)
ABSTRACT Fermentation-based chemical production strategies provide a feasible route for the rapid, safe, and sustainable production of a wide variety of important chemical products, ranging from fuels to pharmaceuticals. These strategies have yet to
Externí odkaz:
https://doaj.org/article/e8e823118eb74a3091c85258ec13f55c
Publikováno v:
Nucleic acids research. 50(15)
Tools for synthetically controlling gene expression are a cornerstone of genetic engineering. CRISPRi and CRISPRa technologies have been applied extensively for programmable modulation of gene transcription, but there are few such tools for targeted
Autor:
Benjamin A. Adler, Tomas Hessler, Brady F Cress, Vivek K. Mutalik, Rodolphe Barrangou, Jillian Banfield, Jennifer A Doudna
CRISPR-Cas13 proteins are RNA-guided RNA nucleases that defend against invasive phages through general, non-specific RNA degradation upon complementary target transcript binding. Despite being RNA nucleases, Cas13 effectors are capable of inhibiting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8da3831a866e9b9e1897e987ecde7ca8
https://doi.org/10.1101/2022.03.25.485874
https://doi.org/10.1101/2022.03.25.485874
Autor:
Benjamin E. Rubin, Spencer Diamond, Brady F. Cress, Alexander Crits-Christoph, Yue Clare Lou, Adair L. Borges, Haridha Shivram, Christine He, Michael Xu, Zeyi Zhou, Sara J. Smith, Rachel Rovinsky, Dylan C. J. Smock, Kimberly Tang, Trenton K. Owens, Netravathi Krishnappa, Rohan Sachdeva, Rodolphe Barrangou, Adam M. Deutschbauer, Jillian F. Banfield, Jennifer A. Doudna
Publikováno v:
Nature microbiology, vol 7, iss 1
Nat Microbiol
Nat Microbiol
Knowledge of microbial gene functions comes from manipulating the DNA of individual strains in isolation from their natural communities. While this approach to microbial genetics has been foundational, its requirement for culturable microorganisms ha
Autor:
Gyoo Yeol Jung, Zhengtao Wang, Mattheos A. G. Koffas, Rufeng Wang, John C. Hordines, Brady F. Cress, Zheng Yang, Shujuan Zhao
Publikováno v:
ACS Synthetic Biology. 8:2121-2130
A common challenge in the assembly and optimization of plant natural product biosynthetic pathways in recombinant hosts is the identification of gene orthologues that will result in best production titers. Here, we describe the modular assembly of a