Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Brady Barron"'
Autor:
Annayya R. Aroor, Javad Habibi, Hemanth Kumar Kandikattu, Mona Garro-Kacher, Brady Barron, Dongqing Chen, Melvin R. Hayden, Adam Whaley-Connell, Shawn B. Bender, Thomas Klein, Jaume Padilla, James R. Sowers, Bysani Chandrasekar, Vincent G. DeMarco
Publikováno v:
Cardiovascular Diabetology, Vol 16, Iss 1, Pp 1-15 (2017)
Abstract Background Diastolic dysfunction (DD), a hallmark of obesity and primary defect in heart failure with preserved ejection fraction, is a predictor of future cardiovascular events. We previously reported that linagliptin, a dipeptidyl peptidas
Externí odkaz:
https://doaj.org/article/a266ba0d033d4548a9a0c5f250cb2a1d
Autor:
Luis A. Martinez-Lemus, Annayya R. Aroor, Francisco I. Ramirez-Perez, Guanghong Jia, Javad Habibi, Vincent G. DeMarco, Brady Barron, Adam Whaley-Connell, Ravi Nistala, James R. Sowers
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Obese premenopausal women lose their sex related cardiovascular disease protection and develop greater arterial stiffening than age matched men. In female mice, we have shown that consumption of a Western diet (WD), high in fat and refined sugars, is
Externí odkaz:
https://doaj.org/article/0d2ffd89d1fc4870b097bf206885df63
Autor:
J. Iker Etchegaray, Shannon Kelley, Kristen Penberthy, Laura Karvelyte, Yosuke Nagasaka, Sofia Gasperino, Soumen Paul, Vikram Seshadri, Michael Raymond, Ana Royo Marco, Jonathan Pinney, Marta Stremska, Brady Barron, Christopher Lucas, Nishikant Wase, Yong Fan, Emil Unanue, Bijoy Kundu, Tal Burstyn-Cohen, Justin Perry, Jayakrishna Ambati, Kodi S. Ravichandran
Publikováno v:
Etchegaray, J I, Kelley, S, Penberthy, K K, Karvelyte, L, Nagasaka, Y, Gasperino, S, Paul, S, Seshadri, V, Raymond, M H, Marco, A R, Pinney, J, Stremska, M E, Barron, B, Lucas, C D, Wase, N, Fan, Y, Unanue, E, Kundu, B, Burstyn-Cohen, T, Perry, J S A, Jayakrishna, A & Ravichandran, K S 2023, ' Phagocytosis in the retina promotes local insulin production in the eye ', Nature Metabolism . https://doi.org/10.1038/s42255-022-00728-0
The retina is highly metabolically active, relying on glucose uptake and aerobic glycolysis. Situated in close contact to photoreceptors, a key function of cells in the retinal pigment epithelium (RPE) is phagocytosis of damaged photoreceptor outer s
Autor:
Aroor, Annayya R., Jia, Guanghong, Habibi, Javad, Sun, Zhe, Ramirez-Perez, Francisco I., Brady, Barron, Chen, Dongqing, Martinez-Lemus, Luis A., Manrique, Camila, Nistala, Ravi, Whaley-Connell, Adam T., Demarco, Vincent G., Meininger, Gerald A., Sowers, James R.
Publikováno v:
In Metabolism September 2017 74:32-40
Autor:
Christopher D. Lucas, Christopher B. Medina, Finnius A. Bruton, David A. Dorward, Michael H. Raymond, Turan Tufan, J. Iker Etchegaray, Brady Barron, Magdalena E. M. Oremek, Sanja Arandjelovic, Emily Farber, Suna Onngut-Gumuscu, Eugene Ke, Moira K. B. Whyte, Adriano G. Rossi, Kodi S. Ravichandran
Publikováno v:
SCIENCE IMMUNOLOGY
Lucas, C D, Medina, C B, Bruton, F, Dorward, D, Raymond, M H, Tufan, T, Etchegaray, J I, Barron, B, Oremek, M, Arandjelovic, S, Farber, E, Onngut-Gumuscu, S, Ke, E, Whyte, M K B, Rossi, A G & Ravichandran, K S 2022, ' Pannexin 1 drives efficient epithelial repair after tissue injury ', Science Immunology, vol. 7, no. 71, eabm4032 . https://doi.org/10.1126/sciimmunol.abm4032
Lucas, C D, Medina, C B, Bruton, F, Dorward, D, Raymond, M H, Tufan, T, Etchegaray, J I, Barron, B, Oremek, M, Arandjelovic, S, Farber, E, Onngut-Gumuscu, S, Ke, E, Whyte, M K B, Rossi, A G & Ravichandran, K S 2022, ' Pannexin 1 drives efficient epithelial repair after tissue injury ', Science Immunology, vol. 7, no. 71, eabm4032 . https://doi.org/10.1126/sciimmunol.abm4032
Epithelial tissues such as lung and skin are exposed to the environment and therefore particularly vulnerable to damage during injury or infection. Rapid repair is therefore essential to restore function and organ homeostasis. Dysregulated epithelial
Autor:
Sho Morioka, Daiki Kajioka, Yusuke Yamaoka, Rochelle M. Ellison, Turan Tufan, Inge L. Werkman, Shinji Tanaka, Brady Barron, Satoshi T. Ito, Sarah Kucenas, Mark D. Okusa, Kodi S. Ravichandran
Publikováno v:
Cell. 185:4887-4903.e17
Our bodies turn over billions of cells daily via apoptosis and are in turn cleared by phagocytes via the process of "efferocytosis." Defects in efferocytosis are now linked to various inflammatory diseases. Here, we designed a strategy to boost effer