Genetic inactivation of SARM1 axon degeneration pathway improves outcome trajectory after experimental traumatic brain injury based on pathological, radiological, and functional measures.

Autor: Bradshaw, Donald V.^1,2 (AUTHOR), Knutsen, Andrew K.^3,4 (AUTHOR), Korotcov, Alexandru^3,4 (AUTHOR), Sullivan, Genevieve M.² (AUTHOR), Radomski, Kryslaine L.^2,4 (AUTHOR), Dardzinski, Bernard J.^3,4,5 (AUTHOR), Zi, Xiaomei² (AUTHOR), McDaniel, Dennis P.⁶ (AUTHOR), Armstrong, Regina C.^1,2,4 (AUTHOR) regina.armstrong@usuhs.edu

Publikováno v: Acta Neuropathologica Communications. 5/17/2021, Vol. 9 Issue 1, p1-19. 19p.

Repetitive Blast Exposure Produces White Matter Axon Damage without Subsequent Myelin Remodeling: In Vivo Analysis of Brain Injury Using Fluorescent Reporter Mice.

Autor: Bradshaw DV Jr; Graduate Program in Neuroscience, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; Department of Anatomy, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA., Kim Y; Center for Neuroscience and Regenerative Medicine, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; Department of Anatomy, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA., Fu A; Center for Neuroscience and Regenerative Medicine, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; Department of Anatomy, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA., Marion CM; Graduate Program in Neuroscience, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; Department of Anatomy, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; Department of Neuroscience, Wexner Medical Center, Ohio State University, Columbus, Ohio, USA., Radomski KL; Center for Neuroscience and Regenerative Medicine, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; Department of Anatomy, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA., McCabe JT; Graduate Program in Neuroscience, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; Center for Neuroscience and Regenerative Medicine, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; Department of Anatomy, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA., Armstrong RC; Graduate Program in Neuroscience, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; Center for Neuroscience and Regenerative Medicine, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; Department of Anatomy, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.

Publikováno v: Neurotrauma reports [Neurotrauma Rep] 2021 Mar 31; Vol. 2 (1), pp. 180-192. Date of Electronic Publication: 2021 Mar 31 (Print Publication: 2021).