Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Bradley Whitman"'
Autor:
Bert C. Lynn, Melissa A. Bradley-Whitman, Erin L. Abner, Stephen W. Scheff, Mark A. Lovell, Kelly N. Roberts
Publikováno v:
Brain injury. 32(3)
BACKGROUND Although elevated serum levels of visinin-like protein 1 (VILIP-1), a neuron-specific calcium sensor protein, are associated with ischaemic stroke, only a single study has evaluated VILIP-1 as a biomarker of traumatic brain injury (TBI). T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b7d34dcb9b2ada641407c9e20e6dbe
https://pubmed.ncbi.nlm.nih.gov/29283288
https://pubmed.ncbi.nlm.nih.gov/29283288
Publikováno v:
Journal of molecular neuroscience : MN. 63(2)
Epigenetic modifications to cytosine have been shown to regulate transcription in cancer, embryonic development, and recently neurodegeneration. While cytosine methylation studies are now common in neurodegenerative research, hydroxymethylation studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae08dabc84c7771b089b81ecfb4ae69
https://pubmed.ncbi.nlm.nih.gov/28866733
https://pubmed.ncbi.nlm.nih.gov/28866733
Akademický článek
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Autor:
Christopher M. Norris, Tina L. Beckett, M. Paul Murphy, Melissa A. Bradley-Whitman, Bert C. Lynn, Mark A. Lovell, Shuling X. Fister
Because traditional approaches to drug development for Alzheimer's disease are becoming increasingly expensive and in many cases disappointingly unsuccessful, alternative approaches are required to shift the paradigm. Following leads from investigati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c5c617a7becda98f02a6d75c60d73e
https://europepmc.org/articles/PMC6025774/
https://europepmc.org/articles/PMC6025774/
Publikováno v:
Journal of Alzheimer's disease : JAD. 47(3)
Specific biomarkers in a readily accessible biological fluid, such as blood, could aid in the identification, characterization, validation, and routine monitoring of Alzheimer's disease (AD) progression. In the current study, levels of the previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a3d3f2d25dd2758b58e826e769aeb7
https://pubmed.ncbi.nlm.nih.gov/26401710
https://pubmed.ncbi.nlm.nih.gov/26401710
Publikováno v:
Archives of toxicology. 89(7)
Increasing evidence suggests free radical mediated oxidation of biological substrates is a key feature of Alzheimer’s disease (AD) pathogenesis. While it has long been established that biomarkers of lipid peroxidation (LPO) are elevated in AD brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad633ea51cbbe341cbafd211e2394c3c
https://pubmed.ncbi.nlm.nih.gov/25895140
https://pubmed.ncbi.nlm.nih.gov/25895140
Akademický článek
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Publikováno v:
Stroke. 45
BACKGROUND: Pre-hospital detection of ischemic brain injury will exclude stroke mimics and refine patient triage. Using “dipstick” immuno-chromatography, we validated a rapid-sequence method to identify visinin-like protein-1 (VILIP-1), a neurona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f5371d03bc8b75d5fd4df251b25add7
https://doi.org/10.1161/str.45.suppl_1.tmp53
https://doi.org/10.1161/str.45.suppl_1.tmp53
Autor:
Bradley-Whitman Ma, Lovell Ma
Publikováno v:
Journal of Analytical & Bioanalytical Techniques.
Studies of oxidative damage during the progression of Alzheimer’s Disease (AD) suggest a central role in disease pathogenesis. To determine if RNA oxidation increases in the progression of AD levels of oxidized bases from RNA from the superior and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6cd5d4098c3e0e1b0ae85696875bfba
https://doi.org/10.4172/2155-9872.s2-004
https://doi.org/10.4172/2155-9872.s2-004
Autor:
Mark A. Lovell, Michael Paul Murphy, Michael D. Timmons, Melissa A. Bradley-Whitman, Tina L. Beckett, Bert C. Lynn
Publikováno v:
Journal of neurochemistry. 128(2)
Studies of oxidative damage during the progression of Alzheimer's disease (AD) suggest its central role in disease pathogenesis. To investigate levels of nucleic acid oxidation in both early and late stages of AD, levels of multiple base adducts were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065c369905d3cd6866f89dc588db471e
https://pubmed.ncbi.nlm.nih.gov/24032632
https://pubmed.ncbi.nlm.nih.gov/24032632