Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Bradley W. Richmond"'
Autor:
Feng Guo, Li Zhang, Yuzhen Yu, Lu Gong, Shiyue Tao, Rhiannon B. Werder, Shreya Mishra, Yihan Zhou, Wardatul Jannat Anamika, Taotao Lao, Hiroyuki Inuzuka, Yihan Zhang, Betty Pham, Tao Liu, Tiffany S. Tufenkjian, Bradley W. Richmond, Wenyi Wei, Hongmei Mou, Andrew A. Wilson, Ming Hu, Wei Chen, Xiaobo Zhou
Publikováno v:
EBioMedicine, Vol 101, Iss , Pp 105026- (2024)
Summary: Background: An intergenic region at chromosome 4q31 is one of the most significant regions associated with COPD susceptibility and lung function in GWAS. In this region, the implicated causal gene HHIP has a unique epithelial expression patt
Externí odkaz:
https://doaj.org/article/dc2c3f9213be44728d34220a6afa9d82
Autor:
Trishul Siddharthan, Kyle Grealis, Jason P. Kirkness, Tamás Ötvös, Darko Stefanovski, Alex Tombleson, Molly Dalzell, Ernesto Gonzalez, Kinjal Bhatt Nakrani, David Wenger, Michael G. Lester, Bradley W. Richmond, Andreas Fouras, Naresh M. Punjabi
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Rationale X-ray velocimetry (XV) has been utilized in preclinical models to assess lung motion and regional ventilation, though no studies have compared XV-derived physiologic parameters to measures derived through conventional means. Object
Externí odkaz:
https://doaj.org/article/47dd2d6913174144aa84dc2cc2db70ad
Autor:
Linh T. Bui, Nichelle I. Winters, Mei-I Chung, Chitra Joseph, Austin J. Gutierrez, Arun C. Habermann, Taylor S. Adams, Jonas C. Schupp, Sergio Poli, Lance M. Peter, Chase J. Taylor, Jessica B. Blackburn, Bradley W. Richmond, Andrew G. Nicholson, Doris Rassl, William A. Wallace, Ivan O. Rosas, R. Gisli Jenkins, Naftali Kaminski, Jonathan A. Kropski, Nicholas E. Banovich, Human Cell Atlas Lung Biological Network
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Patients with chronic lung disease (CLD) have an increased risk for severe coronavirus disease-19 and poor outcomes. Here the authors compare the transcriptomes of single cells isolated from healthy and CLD lungs to identify molecular characteristics
Externí odkaz:
https://doaj.org/article/8c96b7d10ceb4972b8de290313cf45fb
Publikováno v:
Respiratory Medicine Case Reports, Vol 29, Iss , Pp - (2020)
There are growing reports of adverse health effects from e-cigarette use or vaping. The U.S. Centers for Disease Control and Prevention has reported 2409 cases and 52 deaths associated with e-cigarette use as of December 10, 2019. Vaping has been ass
Externí odkaz:
https://doaj.org/article/65de85fe60064a5b9be856c0f56ed78d
Autor:
Bradley W. Richmond, Robert M. Brucker, Wei Han, Rui-Hong Du, Yongqin Zhang, Dong-Sheng Cheng, Linda Gleaves, Rasul Abdolrasulnia, Dina Polosukhina, Peter E. Clark, Seth R. Bordenstein, Timothy S. Blackwell, Vasiliy V. Polosukhin
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The mechanisms driving lung inflammation and remodelling in chronic obstructive pulmonary disease (COPD) are incompletely understood. Here the authors show that lack of secretory IgA promotes bacterial invasion in small airways, resulting in leukocyt
Externí odkaz:
https://doaj.org/article/eeec5588ef414eeb90b7ce8b57b17590
Autor:
Jonathan A. Kropski, Bradley W. Richmond, Christa F. Gaskill, Robert F. Foronjy, Susan M. Majka
Publikováno v:
Pulmonary Circulation, Vol 8 (2017)
Chronic lung disease (CLD), including pulmonary fibrosis (PF) and chronic obstructive pulmonary disease (COPD), is the fourth leading cause of mortality worldwide. Both are debilitating pathologies that impede overall tissue function. A common co-mor
Externí odkaz:
https://doaj.org/article/c8ae17053bae402a88f99e61a2385f3d
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L652-L665
Club cells are found in human small airways where they play an important role in immune defense, xenobiotic metabolism, and repair after injury. Over the past few years, data from single-cell RNA sequencing (scRNA-seq) studies has generated new insig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4b4b26dc688deac0fd3c9f66d00ced9
https://doi.org/10.1152/ajplung.00192.2022
https://doi.org/10.1152/ajplung.00192.2022
Autor:
Jessica B. Blackburn, Jacob A. Schaff, Sergey Gutor, Rui-Hong Du, David Nichols, Taylor Sherrill, Austin J. Gutierrez, Matthew K. Xin, Nancy Wickersham, Yong Zhang, Michael J. Holtzman, Lorraine B. Ware, Nicholas E. Banovich, Jonathan A. Kropski, Timothy S. Blackwell, Bradley W. Richmond
Publikováno v:
American journal of respiratory cell and molecular biology. 67(3)
Loss of secretory IgA (SIgA) is common in chronic obstructive pulmonary disease (COPD) small airways and likely contributes to disease progression. We hypothesized that loss of SIgA results from reduced expression of pIgR (polymeric immunoglobulin re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4faf146e7c33a22350bdd9f083087bcd
https://pubmed.ncbi.nlm.nih.gov/35704450
https://pubmed.ncbi.nlm.nih.gov/35704450
Autor:
Sergey S. Gutor, Rodrigo I. Salinas, David S. Nichols, Julia M. R. Bazzano, Wei Han, Jason J. Gokey, Georgii Vasiukov, James D. West, Dawn C. Newcomb, Anna E. Dikalova, Bradley W. Richmond, Sergey I. Dikalov, Timothy S. Blackwell, Vasiliy V. Polosukhin
Publikováno v:
bioRxiv
Soldiers deployed to Iraq and Afghanistan have a higher prevalence of respiratory symptoms than non-deployed military personnel and some have been shown to have a constellation of findings on lung biopsy termed post-deployment respiratory syndrome (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40a846fd8dda9dd7802cb58e51ba0cf
https://europepmc.org/articles/PMC10245576/
https://europepmc.org/articles/PMC10245576/
Autor:
Sergey S. Gutor, Bradley W. Richmond, Vineet Agrawal, Evan L. Brittain, Matthew F. Mart, Ciara M. Shaver, Pingsheng Wu, Taryn K. Boyle, Ravinder R. Mallugari, Katrina Douglas, Robert N. Piana, Joyce E. Johnson, Robert F. Miller, John H. Newman, Timothy S. Blackwell, Vasiliy V. Polosukhin
BackgroundIncreased frequency of exertional dyspnea has been documented in U.S. military personnel after deployment to Southwest Asia and Afghanistan. We studied whether continued exertional dyspnea in this patient population is associated with pulmo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af8df281667bb561546cda53f5e7076e
https://doi.org/10.1101/2023.05.15.23289956
https://doi.org/10.1101/2023.05.15.23289956