Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bradley W. Beeler"'
Publikováno v:
Cureus.
Publikováno v:
Cureus
Hemophagocytic lymphohistiocytosis (HLH) is a severe systemic inflammatory syndrome that is often fatal. In the adult population, it is believed to develop secondary to immune dysregulation due to rheumatologic, infectious, malignant, and recently, i
Publikováno v:
Transfusion. 60:30-35
Background Hyperhemolysis syndrome (HHS) is a posttransfusion complication most frequently seen in sickle cell disease (SCD), characterized by rapid destruction of transfused and autologous red blood cells (RBCs), resulting in reticulocytopenia and a
Publikováno v:
Military medicine. 186(5-6)
Neurofibromatosis type 1 (NF1) is an autosomal dominant condition affecting 1 in 3,500 people resulting from an NF1 gene mutation that encodes the nonfunctional protein neurofibromin mutant. Neurofibromin is a negative regulator of RAS signaling invo
Publikováno v:
Biology of Blood and Marrow Transplantation. 26:S227-S228
Anaplastic lymphoma-kinase (ALK) positive large B cell lymphoma (LBCL) is a rare, aggressive lymphoma with high relapse rates and poor response to standard cytotoxic therapy. Brigatinib, a next-generation multi-kinase inhibitor that blocks signal tra
Autor:
Brendan C Graham, Michael B. Osswald, Bradley W Beeler, Andrew P. Cap, Nay Win, Aaron T. Henderson, Lauren E. Lee
Publikováno v:
Blood. 132:4933-4933
Hyperhemolysis syndrome (HHS) is a rare, life-threatening complication of red blood cell (RBC) transfusion characterized by fevers, pain, reticulocytopenia and hemolysis of both native and allogeneic RBCs. Management is not standardized. While the pa
Autor:
Sanjay K. Singh, David J. Hammond, Antonio E. Rusiñol, James A. Thompson, Bradley W. Beeler, Alok Agrawal, Michael K. Pangburn, Lawrence A. Potempa
Publikováno v:
Journal of Biological Chemistry. 285:36235-36244
C-reactive protein (CRP) is a phylogenetically conserved protein; in humans, it is present in the plasma and at sites of inflammation. At physiological pH, native pentameric CRP exhibits calcium-dependent binding specificity for phosphocholine. In th
Publikováno v:
Clinica Chimica Acta. 409:143-144
Dear Editor, We recently reported that C-reactive protein (CRP), when present with the small-molecule compound phosphoethanolamine (PEt) (Sigma-Aldrich), acquired the capability to bind to native low-density lipoprotein (LDL), and that PEt enhanced t
Autor:
Lee, Lauren E., Beeler, Bradley W., Graham, Brendan C., Cap, Andrew P., Win, Nay, Chen, Frederick
Publikováno v:
Transfusion; Jan2020, Vol. 60 Issue 1, p30-35, 6p, 1 Graph