Single-dose serotonergic stimulation shows widespread effects on functional brain connectivity

Autor: Najmeh Khalili-Mahani, Jeroen van der Grond, Serge A.R.B. Rombouts, Joop M. A. van Gerven, Helene C. van Gorsel, Bernadet L. Klaassens, Brandon Whitcher, Bradley T. Wyman

Publikováno v: NeuroImage, 122, 440-450

The serotonergic system is widely distributed throughout the central nervous system. It is well known as a mood regulating system, although it also contributes to many other functions. With resting state functional magnetic resonance imaging (RS-fMRI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd15f7e8f1b58332b1eaf67fc2adefa6
https://doi.org/10.1016/j.neuroimage.2015.08.012

Changes in MR relaxation times of the meniscus with acute loading: An in vivo pilot study in knee osteoarthritis

Autor: Richard B. Souza, Thomas M. Link, Xiaojuan Li, Sharmila Majumdar, Marie-Pierre Hellio Le Graverand-Gastineau, Karupppasamy Subburaj, Bradley T. Wyman

Publikováno v: Journal of Magnetic Resonance Imaging. 41:536-543

THE MENISCUS, A fibrocartilaginous tissue found within the knee joint, is responsible for joint congruity, shock dissipation, load transmission, lubrication, and stability of the joint (1,2). The mechanical function of the meniscus largely depends on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8819be23f538d9615cd1b9443e834346
https://doi.org/10.1002/jmri.24546

Bapineuzumab for mild to moderate Alzheimer's disease in two global, randomized, phase 3 trials

Autor: Tom McRae, Gerald Luscan, Prisca Lucas, Kasia Lobello, David Li, Mercè Boada, Achim Gass, Sadao Katayama, Lingfeng Yang, H. Robert Brashear, Lisa Hua, Ronald Black, Michael Tuchman, Kevin Booth, Bruno Vellas, Rik Vandenberghe, Philip Scheltens, Iona Evans, Bradley T. Wyman, Jochen B. Fiebach, Juha O. Rinne, Derek L. G. Hill

Publikováno v: Alzheimer's Research & Therapy
Vandenberghe, R, Rinne, J O, Boada, M, Katayama, S, Scheltens, P, Vellas, B, Tuchman, M, Gass, A, Fiebach, J B, Hill, D, Lobello, K, Li, D, McRae, T, Lucas, P, Evans, I, Booth, K, Luscan, G, Wyman, B T, Hua, L, Yang, L, Brashear, H R, Black, R S & Bapineuzumab 3000 and 3001 Clinical Study Investigators 2016, ' Bapineuzumab for mild to moderate Alzheimer's disease in two global, randomized, phase 3 trials ', Alzheimer's Research & Therapy, vol. 8, no. 1, 18 . https://doi.org/10.1186/s13195-016-0189-7
Alzheimer's Research & Therapy, 8(1):18. BioMed Central

Background Our objective was to evaluate the efficacy (clinical and biomarker) and safety of intravenous bapineuzumab in patients with mild to moderate Alzheimer’s disease (AD). Methods Two of four phase 3, multicenter, randomized, double-blind, pl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84132c233a2e65697604ddfa3a7a1bbc
https://doi.org/10.1186/s13195-016-0189-7

Standardization of analysis sets for reporting results from ADNI MRI data

Autor: Nick C. Fox, Chahin Pachai, Ronald J. Killiany, Matthew L. Senjem, Paul K. Crane, Clifford R. Jack, Joyce Suhy, Derek L. G. Hill, Patricia E. Cole, Charles DeCarli, Jeffrey L. Gunter, Norbert Schuff, Matt A. Bernstein, Karen Crawford, Paul M. Thompson, Bradley T. Wyman, Michael W. Weiner, Adam J. Schwarz, Danielle J Harvey, Owen Carmichael

Publikováno v: Alzheimer's & Dementia. 9:332-337

The Alzheimer's Disease Neuroimaging Initiative (ADNI) three-dimensional T 1 -weighted magnetic resonance imaging (MRI) acquisitions provide a rich data set for developing and testing analysis techniques for extracting structural endpoints. To promot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9bb71df2c049bbe16d81968a61a018
https://doi.org/10.1016/j.jalz.2012.06.004

Changes in Brain Volume with Bapineuzumab in Mild to Moderate Alzheimer's Disease

Autor: Gregg Keith M, Steven Einstein, Nick C. Fox, Enchi Liu, Iulia Cristina Tudor, Casper Nielsen, Bradley T. Wyman, Michael Grundman, H. Robert Brashear, Eric C. Yuen, Shona Clegg, Yuan Lu, Jianing Di, Gerald Novak, Peter C. Collins

Publikováno v: Journal of Alzheimer's disease : JAD. 49(4)

Background: Bapineuzumab, an anti-amyloid-β monoclonal antibody, was evaluated in two placebo-controlled trials in APOE*ɛ4 carriers and noncarriers, respectively, with Alzheimer’s disease. Objectives: A volumetric magnetic resonance imaging subst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e2443c1059efa6cc108e569918fa56
https://pubmed.ncbi.nlm.nih.gov/26639957