Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Bradley T. Estes"'
Autor:
Dianne Little, Stephen Johnson, Jonathan Hash, Steven A. Olson, Bradley T. Estes, Franklin T. Moutos, B. Duncan X. Lascelles, Farshid Guilak
Publikováno v:
Journal of Experimental Orthopaedics, Vol 3, Iss 1, Pp n/a-n/a (2016)
Abstract Background The hip is one of the most common sites of osteoarthritis in the body, second only to the knee in prevalence. However, current animal models of hip osteoarthritis have not been assessed using many of the functional outcome measure
Externí odkaz:
https://doaj.org/article/4eb47bdd19b6401e8b7423ad3048b665
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 40(8)
Biological resurfacing of entire articular surfaces represents a challenging strategy for treatment of cartilage degeneration that occurs in osteoarthritis. Not only does this approach require anatomically sized and functional engineered cartilage, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec98bda94bff4a4979cacb53ac273eb
https://pubmed.ncbi.nlm.nih.gov/34812518
https://pubmed.ncbi.nlm.nih.gov/34812518
Autor:
Bradley T. Estes, Megan A. Carson, Jonathan W. Stallrich, Franklin T. Moutos, Vincent P. Willard, Deborah J. Veis, Masataka Enomoto, Jeffrey M. Toth, B. Duncan X. Lascelles, Peter Eggert, Dianne Little, Farshid Guilak
Publikováno v:
Science advances. 7(38)
Articular cartilage has unique load-bearing properties but has minimal capacity for intrinsic repair. Here, we used three-dimensional weaving, additive manufacturing, and autologous mesenchymal stem cells to create a tissue-engineered, bicomponent im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad35bdbfb6b5b9ad9a9158475f78b1cd
https://pubmed.ncbi.nlm.nih.gov/34524840
https://pubmed.ncbi.nlm.nih.gov/34524840
Autor:
Patrick B. Wu, Cameron J Bloomquist, Robert Langer, Sarah N Yu, Hyoungshin Park, Jean F. Welter, Lisa E. Freed, Franklin T. Moutos, Benjamin L. Larson, Bradley T. Estes, Farshid Guilak
Publikováno v:
J Tissue Eng Regen Med
PMC
PMC
The development of mechanically functional cartilage and bone tissue constructs of clinically relevant size, as well as their integration with native tissues, remains an important challenge for regenerative medicine. The objective of this study was t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3412648061b5837cec315ea926e5e2
https://doi.org/10.1002/term.2899
https://doi.org/10.1002/term.2899
Autor:
Jagadeesh K. Venkatesan, Franklin T. Moutos, Farshid Guilak, Janina Frisch, Ana Rey-Rico, Magali Cucchiarini, Gertrud Schmitt, Bradley T. Estes, Henning Madry
Publikováno v:
Human Gene Therapy. 29:1277-1286
Combining gene therapy approaches with tissue engineering procedures is an active area of translational research for the effective treatment of articular cartilage lesions, especially to target chondrogenic progenitor cells such as those derived from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43565477208b608acd791bee7f88eb81
https://doi.org/10.1089/hum.2017.165
https://doi.org/10.1089/hum.2017.165
Autor:
Yu Sn, Jean F. Welter, Hyoungshin Park, Bloomquist Cj, Franklin T. Moutos, Benjamin L. Larson, Patrick B. Wu, Farshid Guilak, Robert Langer, Bradley T. Estes, Lisa E. Freed
The development of mechanically functional cartilage and bone tissue constructs of clinically relevant size, as well as their integration with native tissues, remain important challenges for regenerative medicine. The objective of this study was to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ab39f5f1b5f20b215b472b9174897d
https://doi.org/10.1101/395202
https://doi.org/10.1101/395202
Autor:
Xuanhe Zhao, Kristen L. Moffat, Bradley T. Estes, Sara J. Oswald, Kelsey Goon, Farshid Guilak, Franklin T. Moutos
Publikováno v:
Macromolecular bioscience. 18(10)
Biomaterial scaffolds play multiple roles in cartilage tissue engineering, including controlling architecture of newly formed tissue while facilitating growth of embedded cells and simultaneously providing functional properties to withstand the mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c11d9f2bb784fb93efc6278d00a63b
https://pubmed.ncbi.nlm.nih.gov/30040175
https://pubmed.ncbi.nlm.nih.gov/30040175
Autor:
Robert L. Mauck, Farshid Guilak, Kerry O Orji, Alexander L. Neuwirth, Marcelo Batista Bonadio, James M. Friedman, Henning Madry, Mackenzie L. Sennett, George R. Dodge, Franklin T. Moutos, James L. Carey, Bradley T. Estes, Niobra M. Keah
Publikováno v:
Cartilage. 9(4)
Objective To test different fixation methods of a 3-dimensionally woven poly(ϵ-caprolactone) (PCL) scaffold within chondral defects of a weightbearing large animal model. Methods Full thickness chondral defects were made in the femoral condyles of 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de5f4d24f2fd8fb7a9648b86f5d98d0
https://pubmed.ncbi.nlm.nih.gov/28397530
https://pubmed.ncbi.nlm.nih.gov/28397530
Publikováno v:
Advanced Functional Materials. 23:5833-5839
The development of synthetic biomaterials that possess mechanical properties that mimic those of native tissues remains an important challenge to the field of materials. In particular, articular cartilage is a complex nonlinear, viscoelastic, and ani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cfd8f765bfc8714431ee24257144e00
https://doi.org/10.1002/adfm.201300483
https://doi.org/10.1002/adfm.201300483
Autor:
J. Brice Weinberg, Paul H. Ousema, Arnold I. Caplan, Farshid Guilak, Bradley T. Estes, Donald P. Lennon, Franklin T. Moutos
Publikováno v:
Biomaterials. 33:8967-8974
Tissue-engineered constructs designed to treat large cartilage defects or osteoarthritic lesions may be exposed to significant mechanical loading as well as an inflammatory environment upon implantation in an injured or diseased joint. We hypothesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52041e1d3fd5f4375f53bfda4a1ea36b
https://doi.org/10.1016/j.biomaterials.2012.08.045
https://doi.org/10.1016/j.biomaterials.2012.08.045