Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Bradley T. Andresen"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/b8d7b8b3d3c742bf8c135626273ba80d
Autor:
Md Abdullah Shamim, Ayaz Shahid, Pabitra K. Sardar, Steven Yeung, Jeremiah Reyes, Jenny Kim, Cyrus Parsa, Robert Orlando, Jeffrey Wang, Kristen M. Kelly, Frank L. Meyskens, Bradley T. Andresen, Ying Huang
Publikováno v:
Nanomaterials, Vol 13, Iss 5, p 929 (2023)
The R-carvedilol enantiomer, present in the racemic mixture of the chiral drug carvedilol, does not bind to the β-adrenergic receptors, but exhibits skin cancer preventive activity. For skin delivery, R-carvedilol-loaded transfersomes were prepared
Externí odkaz:
https://doaj.org/article/3d025cf03a8f49b5987bc6fd3a863216
Autor:
Mengbing Chen, Md Abdullah Shamim, Ayaz Shahid, Steven Yeung, Bradley T. Andresen, Jeffrey Wang, Vijaykumar Nekkanti, Frank L. Meyskens, Kristen M. Kelly, Ying Huang
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1151 (2020)
The β-blocker carvedilol has been shown to prevent skin carcinogenesis in vitro and in vivo. Since systemic absorption of the β-blocker may cause cardiovascular disturbance, we developed a carvedilol loaded transfersome for skin-targeted delivery.
Externí odkaz:
https://doaj.org/article/ed49c9635b2845b5ab89447d4593eda0
Autor:
Shane D Anderson, Asna Tabassum, Jae Kyung Yeon, Garima Sharma, Priscilla Santos, Tik Hang Soong, Yin Win Thu, Isaac Nies, Tomomi Kurita, Andrew Chandler, Abdelaziz Alsamarah, Rhye-Samuel Kanassatega, Yun L Luo, Wesley M Botello-Smith, Bradley T Andresen
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 11, p e1007719 (2020)
Angiotensin II type 1 receptor (AT1R) blockers (ARBs) are among the most prescribed drugs. However, ARB effectiveness varies widely, which may be due to non-synonymous single nucleotide polymorphisms (nsSNPs) within the AT1R gene. The AT1R coding seq
Externí odkaz:
https://doaj.org/article/9057f3767c6a46328700c2fefa4f9edc
Autor:
Kristan H Cleveland, Sherry Liang, Andy Chang, Kevin M Huang, Si Chen, Lei Guo, Ying Huang, Bradley T Andresen
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217038 (2019)
Carvedilol is reported to prevent cancers in humans and animal models. However, a molecular mechanism has yet to be established, and the extent to which other β-blockers are chemopreventive remains relatively unknown. A comparative pharmacological a
Externí odkaz:
https://doaj.org/article/0bd2d538206844c3a004f3bc552eb2ca
Autor:
Ying Huang, Bradley T. Andresen, Frank L. Meyskens, Robert Orlando, Cyrus Parsa, Kristan H. Cleveland, Etuajie Oiyemhonlan, Steven Yeung, Sherry Liang, Kevin M. Huang
Supplementary Figure Legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26a284f26aeec453a08684aee10d3295
https://doi.org/10.1158/1940-6207.22534061.v1
https://doi.org/10.1158/1940-6207.22534061.v1
Autor:
Ying Huang, Bradley T. Andresen, Robert Orlando, Cyrus Parsa, Kristan H. Cleveland, Mengbing Chen, Ayaz Shahid, Md Abdullah Shamim, Sherry Liang
Skin cancer is the most common malignancy worldwide and is rapidly rising in incidence, representing a significant public health challenge. The β-blocker, carvedilol, has shown promising effects in preventing skin cancer. However, as a potent β-blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2341dad1490d8615ca2e55bddea42ed4
https://doi.org/10.1158/1940-6207.c.6547555.v1
https://doi.org/10.1158/1940-6207.c.6547555.v1
Autor:
Ying Huang, Bradley T. Andresen, Frank L. Meyskens, Robert Orlando, Cyrus Parsa, Kristan H. Cleveland, Etuajie Oiyemhonlan, Steven Yeung, Sherry Liang, Kevin M. Huang
Supplemental Figure S1. UV lamp emission spectrum. UVP supplied spectrum of the UV bulb #95-0042-08 and #95-0043-13. Spectrum modified to show a fill under the curve and delete values under zero. The range corresponds to the range depicted for carved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c427d52bb1b5eae585e4dff77a153f3
https://doi.org/10.1158/1940-6207.22534067
https://doi.org/10.1158/1940-6207.22534067
Autor:
Ayaz Shahid, Mengbing Chen, Carol Lin, Bradley T. Andresen, Cyrus Parsa, Robert Orlando, Ying Huang
Publikováno v:
Cancers; Volume 15; Issue 3; Pages: 583
The current study evaluated the effects of the β-blocker carvedilol on benzo(a)pyrene (B(a)P) and its active metabolite benzo(a)pyrene diol epoxide (BPDE)-induced lung toxicity, inflammation and carcinogenesis and explored the potential mechanisms.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e49bb2b6644e2574cb6f492b6ad631
Autor:
Xia Li, Bingsen Zhou, Tiantian Liu, Steven Yeung, Cyrus Parsa, Zhijun Wang, Ying Huang, Wei Wu, Robert Orlando, Mandy Liu, Bradley T. Andresen, Charles Wang, Yilong Zhang
Publikováno v:
Precision Clinical Medicine. 4:231-245
The medicinal mushroom Ganoderma lucidum (GL, Reishi or Lingzhi) exhibits an inhibitory effect on cancers. However, the underlying mechanism of the antitumor activity of GL is not fully understood. In this study, we characterized the gene networks re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::381972f1fcda6c69a50740560d36a511
https://doi.org/10.1093/pcmedi/pbab023
https://doi.org/10.1093/pcmedi/pbab023