Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Bradley T Scroggins"'
Autor:
Thomas L Prince, Toshiki Kijima, Manabu Tatokoro, Sunmin Lee, Shinji Tsutsumi, Kendrick Yim, Candy Rivas, Sylvia Alarcon, Harvey Schwartz, Kofi Khamit-Kush, Bradley T Scroggins, Kristin Beebe, Jane B Trepel, Len Neckers
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141786 (2015)
The two cytosolic/nuclear isoforms of the molecular chaperone HSP90, stress-inducible HSP90α and constitutively expressed HSP90β, fold, assemble and maintain the three-dimensional structure of numerous client proteins. Because many HSP90 clients ar
Externí odkaz:
https://doaj.org/article/0ff6f1ea8e0146d899d256ab4307650b
Autor:
Xiuxiu Lu, Monika Chandravanshi, Venkata R. Sabbasani, Snehal Gaikwad, V. Keith Hughitt, Nana Gyabaah-Kessie, Bradley T. Scroggins, Sudipto Das, Wazo Myint, Michelle E. Clapp, Charles D. Schwieters, Marzena A. Dyba, Derek L. Bolhuis, Janusz W. Koscielniak, Thorkell Andresson, Michael J. Emanuele, Nicholas G. Brown, Hiroshi Matsuo, Raj Chari, Deborah E. Citrin, Beverly A. Mock, Rolf E. Swenson, Kylie J. Walters
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Proteasome subunit hRpn13 is partially proteolyzed in certain cancer cell types to generate hRpn13Pru by degradation of its UCHL5/Uch37-binding DEUBAD domain and retention of an intact proteasome- and ubiquitin-binding Pru domain. By using s
Externí odkaz:
https://doaj.org/article/287afc8f95ca4e0dbcecccb50eebdb48
Autor:
Shilpa Patil, Jessica L. Reedy, Bradley T. Scroggins, Ayla O. White, Seokjoo Kwon, Uma Shankavaram, Alfonso López-Coral, Eun Joo Chung, Deborah E. Citrin
Publikováno v:
Aging. 14:1068-1086
Radiation therapy is a commonly used treatment modality for cancer. Although effective in providing local tumor control, radiation causes oxidative stress, inflammation, immunomodulatory and mitogenic cytokine production, extracellular matrix product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe0fd31993401a3b4511ed284d236f5
https://doi.org/10.18632/aging.203890
https://doi.org/10.18632/aging.203890
Autor:
Deborah E. Citrin, Murali C. Krishna, James B. Mitchell, Kazuhiro Ichikawa, Yoichi Takakusagi, Vivian Diaz, Kazutoshi Yamamoto, Carole Sourbier, Jeeva P. Munasinghe, Keita Saito, Ayla O. White, Masayuki Matsuo, Bradley T. Scroggins
Supplemental materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cab1e70de90169aaabdcaac1850f97e
https://doi.org/10.1158/1078-0432.22464960.v1
https://doi.org/10.1158/1078-0432.22464960.v1
Autor:
Deborah E. Citrin, Murali C. Krishna, James B. Mitchell, Kazuhiro Ichikawa, Yoichi Takakusagi, Vivian Diaz, Kazutoshi Yamamoto, Carole Sourbier, Jeeva P. Munasinghe, Keita Saito, Ayla O. White, Masayuki Matsuo, Bradley T. Scroggins
Supplemental Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0289a0cd46b4c84fc4c889dffd0815
https://doi.org/10.1158/1078-0432.22464963
https://doi.org/10.1158/1078-0432.22464963
Autor:
Deborah E. Citrin, Murali C. Krishna, James B. Mitchell, Kazuhiro Ichikawa, Yoichi Takakusagi, Vivian Diaz, Kazutoshi Yamamoto, Carole Sourbier, Jeeva P. Munasinghe, Keita Saito, Ayla O. White, Masayuki Matsuo, Bradley T. Scroggins
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7573067900402292b066eded27ace079
https://doi.org/10.1158/1078-0432.22464966.v1
https://doi.org/10.1158/1078-0432.22464966.v1
Autor:
Deborah E. Citrin, Murali C. Krishna, James B. Mitchell, Kazuhiro Ichikawa, Yoichi Takakusagi, Vivian Diaz, Kazutoshi Yamamoto, Carole Sourbier, Jeeva P. Munasinghe, Keita Saito, Ayla O. White, Masayuki Matsuo, Bradley T. Scroggins
Purpose: To evaluate the potential of hyperpolarized [1-13C]-pyruvate magnetic resonance spectroscopic imaging (MRSI) of prostate cancer as a predictive biomarker for targeting the Warburg effect.Experimental Design: Two human prostate cancer cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f32fe26ac830627bb42f484dd97b04
https://doi.org/10.1158/1078-0432.c.6525876
https://doi.org/10.1158/1078-0432.c.6525876
Autor:
Su I. Chung, Darmood Wei, Luca F. Valle, Grace McKay-Corkum, Ayla O. White, Eun Joo Chung, Kathryn E. Hudak, W. Marston Linehan, Jeffrey Burkeen, Shilpa S. Patil, Bradley T. Scroggins, Deborah Citrin
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 100:344-352
Purpose Specificity protein 1 (SP1) is involved in the transcription of several genes implicated in tumor maintenance. We investigated the effects of mithramycin A (MTA), an inhibitor of SP1 DNA binding, on radiation response. Methods and Materials C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e24f7c2b1c9e5aeb8599b4c628e7d7e
https://doi.org/10.1016/j.ijrobp.2017.09.049
https://doi.org/10.1016/j.ijrobp.2017.09.049
Autor:
W. Marston Linehan, Christopher J. Ricketts, Darmood Wei, Sarah M. Baranes, Len Neckers, Pei-Jyun Liao, Carole Sourbier, Lernik Ohanjanian, L. Spencer Krane, Ming-Hui Wei, Cathy D. Vocke, Paul S. Meltzer, Youfeng Yang, J. Keith Killian, Deborah Citrin, Toshiki Kijima, Bradley T. Scroggins, Benjamin K. Gibbs
Publikováno v:
Oncotarget. 9:10723-10733
Papillary renal cell carcinomas (PRCC) are a histologically and genetically heterogeneous group of tumors that represent 15-20% of all kidney neoplasms and may require diverse therapeutic approaches. Alteration of the NF2 tumor suppressor gene, encod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5bdc37cc699145c6a38d05216fcf410
https://doi.org/10.18632/oncotarget.24112
https://doi.org/10.18632/oncotarget.24112
Autor:
Jeeva Munasinghe, Murali C. Krishna, Yoichi Takakusagi, James Mitchell, Bradley T. Scroggins, Keita Saito, Masayuki Matsuo, Ayla O. White, Vivian Diaz, Deborah Citrin, Carole Sourbier, Kazutoshi Yamamoto, Kazuhiro Ichikawa
Publikováno v:
Clin Cancer Res
Purpose: To evaluate the potential of hyperpolarized [1-13C]-pyruvate magnetic resonance spectroscopic imaging (MRSI) of prostate cancer as a predictive biomarker for targeting the Warburg effect. Experimental Design: Two human prostate cancer cell l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4da2b968cda846b8008f10949d4098
https://europepmc.org/articles/PMC7984723/
https://europepmc.org/articles/PMC7984723/