Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Bradley St. Croix"'
Autor:
Andrew J. Mungall, Yussanne Ma, Sorana Morrissy, Bradley St. Croix, Michelle Kushida, Ana Nikolic, Alex Murison, Mathieu Lupien, Douglas J. Mahoney, Fiona J. Coutinho, Peter B. Dirks, Florence M.G. Cavalli, Richard A. Moore, Paul Guilhamon, Michael D. Taylor, Katrina Ellestad, John J.Y. Lee, Michael J. Johnston, Aly Abdelkareem, Steven Seaman, Marco A. Marra, Nicoletta Ninkovic, Marco Gallo, Franz J. Zemp, Trevor J. Pugh
Publikováno v:
Genome Research. 29:1211-1222
SUMMARYWe investigated the role of 3D genome architecture in instructing functional properties of glioblastoma stem cells (GSCs) by generating the highest-resolution 3D genome maps to-date for this cancer. Integration of DNA contact maps with chromat
Autor:
Rebeca Gonzalez-Pastor, Igor P. Dmitriev, Charles B. Shoemaker, David T. Curiel, Elena A. Kashentseva, Bradley St. Croix, Myungeun Lee, Zhi Hong Lu, Steven Seaman, Jacqueline M. Tremblay
Publikováno v:
J Control Release
For the developing field of gene therapy the successful address of the basic requirement effective gene delivery has remained a critical barrier. In this regard, the "Holy Grail" vector envisioned by the field's pioneers embodied the ability to achie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7bd1354bd0cae24b0a2ae8098fa225
https://europepmc.org/articles/PMC10292108/
https://europepmc.org/articles/PMC10292108/
Autor:
Meijie Tian, Adam Tai-Chi Cheuk, Yong Song, Sivasish Sindiri, Nan Li, Christopher M. Dower, Mitchell Ho, Bradley St Croix, Javed Khan
Publikováno v:
Cancer Research. 80:5871-5871
Background: Neuroblastoma (NB) is the most common extra-cranial solid cancer in children. Although multimodal therapies with differentiating agents and immunotherapy with anti-GD2 antibody and GM-CSF have shown promising results, it remains deadly in
Autor:
Zakaria Grada, Bradley S. Fletcher, Stephen Gottschalk, Meenakshi Hegde, Kevin Aviles-Padilla, Tiara T. Byrd, Bradley St Croix, Kevin Bielamowicz, Nabil Ahmed, Kristen Fousek
Publikováno v:
Cancer Research. 75:B74-B74
Background: Glioblastoma (GBM) is the most common and most aggressive primary brain tumor in adults. With the current standard treatment, survival is poor with substantial treatment related toxicities underscoring the need for new targeted therapies.
Autor:
Tiara T. Byrd, Bradley S. Fletcher, Nabil Ahmed, Kristen Fousek, Kevin Aviles-Padilla, Meenakshi Hegde, Kevin Bielamowicz, Stephen Gottschalk, Bradley St Croix, Zakaria Grada
Publikováno v:
Cancer Research. 74:LB-264
Background: T cells can be genetically modified to express chimeric antigen receptors (CAR) molecules on the surface. These CAR-bearing T cells combine the specificity of an antibody with the killing properties of a T cell for a targeted immunotherap