A 1-Month Ketogenic Diet Increased Mitochondrial Mass in Red Gastrocnemius Muscle, but Not in the Brain or Liver of Middle-Aged Mice

Autor: Zeyu Zhou, Jocelyn Vidales, José A. González-Reyes, Bradley Shibata, Keith Baar, Jennifer M. Rutkowsky, Jon J. Ramsey

Publikováno v: Nutrients, Vol 13, Iss 8, p 2533 (2021)

Alterations in markers of mitochondrial content with ketogenic diets (KD) have been reported in tissues of rodents, but morphological quantification of mitochondrial mass using transmission electron microscopy (TEM), the gold standard for mitochondri

Externí odkaz: https://doaj.org/article/5904fe9e97e64c4398e65e5c48d08c29

Generation of Schwann cell derived melanocytes from hPSCs identifies pro-metastatic factors in melanoma

Autor: Ryan M. Samuel, Albertas Navickas, Ashley Maynard, Eliza A. Gaylord, Kristle Garcia, Samyukta Bhat, Homa Majd, Mikayla N. Richter, Nicholas Elder, Daniel Le, Phi Nguyen, Bradley Shibata, Marta Losa Llabata, Licia Selleri, Diana J. Laird, Spyros Darmanis, Hani Goodarzi, Faranak Fattahi

Publikováno v: bioRxiv

Summary/AbstractThe neural crest (NC) is highly multipotent and generates diverse lineages in the developing embryo. However, spatiotemporally distinct NC populations display differences in fate potential, such as increased gliogenic and parasympathe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed594aa254e5e343e5d5a34952cb6cb5
https://doi.org/10.1101/2023.03.06.531220

Deriving Schwann cells from hPSCs enables disease modeling and drug discovery for diabetic peripheral neuropathy

Autor: Homa Majd, Sadaf Amin, Zaniar Ghazizadeh, Andrius Cesiulis, Edgardo Arroyo, Karen Lankford, Alireza Majd, Sina Farahvashi, Angeline K. Chemel, Mesomachukwu Okoye, Megan D. Scantlen, Jason Tchieu, Elizabeth L. Calder, Valerie Le Rouzic, Bradley Shibata, Abolfazl Arab, Hani Goodarzi, Gavril Pasternak, Jeffery D. Kocsis, Shuibing Chen, Lorenz Studer, Faranak Fattahi

Publikováno v: Cell Stem Cell. 30:632-647.e10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e291548b5a070d937c6a599f6a86596e
https://doi.org/10.1016/j.stem.2023.04.006

Wdfy3 regulates glycophagy, mitophagy, and synaptic plasticity

Autor: Nathaniel Satriya, Eleonora Napoli, Konstantinos Zarbalis, Alexios A Panoutsopoulos, Kira Sterling, Cecilia R Giulivi, P.E. Kysar, Denise M. Imai, Bradley Shibata, David N. Ruskin

Publikováno v: J Cereb Blood Flow Metab
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol 41, iss 12

Autophagy is essential to cell function, as it enables the recycling of intracellular constituents during starvation and in addition functions as a quality control mechanism by eliminating spent organelles and proteins that could cause cellular damag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d50ee5f28f8ab6ab09d229c73f48d35
https://europepmc.org/articles/PMC8669292/

Long-term Evolution and Remodeling of Soft Drusen in Rhesus Macaques

Autor: Yinwen Wang, Sook Hyun Chung, Sara M Thomasy, David Cunefare, Bradley Shibata, Glenn Yiu, Iris Natalie Mollhoff, Sina Farsiu, Jeffrey A. Roberts, Uyen Tu Nguyen

Publikováno v: Investigative Ophthalmology & Visual Science
Investigative ophthalmology & visual science, vol 61, iss 2

Author(s): Yiu, Glenn; Chung, Sook Hyun; Mollhoff, Iris Natalie; Wang, Yinwen; Nguyen, Uyen Tu; Shibata, Bradley; Cunefare, David; Farsiu, Sina; Roberts, Jeffrey; Thomasy, Sara M | Abstract: PurposeTo characterize the evolution and structure of soft

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e13185808d9da269fbe68d787d60910
https://pubmed.ncbi.nlm.nih.gov/32084273