Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Bradley S. Fletcher"'
Autor:
Nabil Ahmed, Brad St. Croix, Bradley S. Fletcher, Meenakshi Hegde, Michael T. Lewis, Matthew J. Ellis, Benjamin Deneen, Poul H. Sorensen, Joachim Koch, Winfried S. Wels, Matthew L. Baker, Suzanne Powell, John Hicks, Nino Rainusso, Daniel Landi, Kevin Bielamowicz, Htoo Zarni Oo, Vita S. Salsman, Lacey Dobrolecki, Steven Seaman, Heba Samaha, Christopher Szot, Antonella Pignata, Kristen Fousek, Tiara T. Byrd
Information about methods and data that further support the claims made in this article. This includes, but is not limited to TEM8 distribution in normal tissues, CAR T cell normalization, additional control groups and CAR toxicity studies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059c2ab76dcfed3e611890416f8bbef3
https://doi.org/10.1158/0008-5472.22417994.v1
https://doi.org/10.1158/0008-5472.22417994.v1
Autor:
Nabil Ahmed, Brad St. Croix, Bradley S. Fletcher, Meenakshi Hegde, Michael T. Lewis, Matthew J. Ellis, Benjamin Deneen, Poul H. Sorensen, Joachim Koch, Winfried S. Wels, Matthew L. Baker, Suzanne Powell, John Hicks, Nino Rainusso, Daniel Landi, Kevin Bielamowicz, Htoo Zarni Oo, Vita S. Salsman, Lacey Dobrolecki, Steven Seaman, Heba Samaha, Christopher Szot, Antonella Pignata, Kristen Fousek, Tiara T. Byrd
L2 2G and L2 3G CAR T cell normalization and functional testing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe823f256230caf791bf1669207c24e
https://doi.org/10.1158/0008-5472.22418006
https://doi.org/10.1158/0008-5472.22418006
Autor:
Nabil Ahmed, Brad St. Croix, Bradley S. Fletcher, Meenakshi Hegde, Michael T. Lewis, Matthew J. Ellis, Benjamin Deneen, Poul H. Sorensen, Joachim Koch, Winfried S. Wels, Matthew L. Baker, Suzanne Powell, John Hicks, Nino Rainusso, Daniel Landi, Kevin Bielamowicz, Htoo Zarni Oo, Vita S. Salsman, Lacey Dobrolecki, Steven Seaman, Heba Samaha, Christopher Szot, Antonella Pignata, Kristen Fousek, Tiara T. Byrd
No overt toxicity detected in mice receiving TEM8 CAR T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43220c88bbd61e7387860d21e71559c4
https://doi.org/10.1158/0008-5472.22418000.v1
https://doi.org/10.1158/0008-5472.22418000.v1
Autor:
Nabil Ahmed, Brad St. Croix, Bradley S. Fletcher, Meenakshi Hegde, Michael T. Lewis, Matthew J. Ellis, Benjamin Deneen, Poul H. Sorensen, Joachim Koch, Winfried S. Wels, Matthew L. Baker, Suzanne Powell, John Hicks, Nino Rainusso, Daniel Landi, Kevin Bielamowicz, Htoo Zarni Oo, Vita S. Salsman, Lacey Dobrolecki, Steven Seaman, Heba Samaha, Christopher Szot, Antonella Pignata, Kristen Fousek, Tiara T. Byrd
TEM8 distribution in normal tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b91f2acad14ec3d3551ac6177dba8a9
https://doi.org/10.1158/0008-5472.22418012
https://doi.org/10.1158/0008-5472.22418012
Autor:
Nabil Ahmed, Brad St. Croix, Bradley S. Fletcher, Meenakshi Hegde, Michael T. Lewis, Matthew J. Ellis, Benjamin Deneen, Poul H. Sorensen, Joachim Koch, Winfried S. Wels, Matthew L. Baker, Suzanne Powell, John Hicks, Nino Rainusso, Daniel Landi, Kevin Bielamowicz, Htoo Zarni Oo, Vita S. Salsman, Lacey Dobrolecki, Steven Seaman, Heba Samaha, Christopher Szot, Antonella Pignata, Kristen Fousek, Tiara T. Byrd
L2 CAR T cells provide a survival advantage and disrupt vessels and tumor architecture in TNBC xenografts .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b9ca39933febc4775e876b27540fe1
https://doi.org/10.1158/0008-5472.22418003
https://doi.org/10.1158/0008-5472.22418003
Autor:
Nabil Ahmed, Brad St. Croix, Bradley S. Fletcher, Meenakshi Hegde, Michael T. Lewis, Matthew J. Ellis, Benjamin Deneen, Poul H. Sorensen, Joachim Koch, Winfried S. Wels, Matthew L. Baker, Suzanne Powell, John Hicks, Nino Rainusso, Daniel Landi, Kevin Bielamowicz, Htoo Zarni Oo, Vita S. Salsman, Lacey Dobrolecki, Steven Seaman, Heba Samaha, Christopher Szot, Antonella Pignata, Kristen Fousek, Tiara T. Byrd
L2 CAR T cells reduce mammosphere formation when compared to irrelevant CAR control cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6bb2e729ea4a30f3acefdca8403f2c
https://doi.org/10.1158/0008-5472.22418009
https://doi.org/10.1158/0008-5472.22418009
Autor:
Nabil Ahmed, Brad St. Croix, Bradley S. Fletcher, Meenakshi Hegde, Michael T. Lewis, Matthew J. Ellis, Benjamin Deneen, Poul H. Sorensen, Joachim Koch, Winfried S. Wels, Matthew L. Baker, Suzanne Powell, John Hicks, Nino Rainusso, Daniel Landi, Kevin Bielamowicz, Htoo Zarni Oo, Vita S. Salsman, Lacey Dobrolecki, Steven Seaman, Heba Samaha, Christopher Szot, Antonella Pignata, Kristen Fousek, Tiara T. Byrd
Mice that received systemic administration of L2 CAR T cells have normal pathology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c438e3436b2714009feb00643b53ce
https://doi.org/10.1158/0008-5472.22417997.v1
https://doi.org/10.1158/0008-5472.22417997.v1
Autor:
Garry Schwartz, Mauricio Lynn, Kim Hien T. Dao, Katherine Walsh, Jed B. Gorlin, Marc Zumberg, Amanda M. VanSandt, Elizabeth A. Griffiths, Aryeh Shander, Bradley S. Fletcher
Publikováno v:
Transfusion. 60:932-939
BACKGROUND Hemoglobin-Based Oxygen Carriers (HBOCs) can act as an "oxygen bridge" in acute severe anemia when transfusion is indicated, but not possible. We present data on 10 Expanded Access (EA) patients treated with high cumulative doses of Hemopu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326301ae90360dc606ba4659eac97ff2
https://doi.org/10.1111/trf.15778
https://doi.org/10.1111/trf.15778
Publikováno v:
International Journal of Hematology and Blood Disorders. 2:1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ddcc7cb5063c9ef3a334e3e3be5bcb2
https://doi.org/10.15226/2639-7986/2/3/00113
https://doi.org/10.15226/2639-7986/2/3/00113
Autor:
Antonella Pignata, Meenakshi Hegde, Kevin Bielamowicz, Winfried S. Wels, Nabil Ahmed, Bradley S. Fletcher, Tiara T. Byrd, Daniel Landi, B St Croix, Joachim Koch, Steven Seaman, Christopher S. Szot, Amanda Wakefield, Kristen Fousek
Publikováno v:
Cancer Research. 76:PD3-07
Background: Triple Negative Breast Cancer (TNBC) refers to an aggressive subtype of breast cancer negative for HER2, estrogen and progesterone receptors. Lacking these receptors, individuals with TNBC do not benefit from many of the targeted therapie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bba7a20ec566958315a86b32dd191423
https://doi.org/10.1158/1538-7445.sabcs15-pd3-07
https://doi.org/10.1158/1538-7445.sabcs15-pd3-07