Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Bradley R, Jones"'
Autor:
Jane J. Chung-Do, Samantha Keaulana Scott, Bradley R. Jones, Mele A. Look, Deborah A. Taira, Neal A. Palafox, Kamahanahokulani Farrar, Marjorie K. Leimomi M. Mau
Publikováno v:
Frontiers in Public Health, Vol 11 (2024)
To address the history of unethical research and community distrust in research among Native Hawaiian and Pacific Islander communities, we developed the “Community 101 for Researchers” training program, which was launched in 2014 to enhance the c
Externí odkaz:
https://doaj.org/article/a3192196a8874ea0ac4c92f294315832
Autor:
Natalie N. Kinloch, Aniqa Shahid, Winnie Dong, Don Kirkby, Bradley R. Jones, Charlotte J. Beelen, Daniel MacMillan, Guinevere Q. Lee, Talia M. Mota, Hanwei Sudderuddin, Evan Barad, Marianne Harris, Chanson J. Brumme, R. Brad Jones, Mark A. Brockman, Jeffrey B. Joy, Zabrina L. Brumme
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTIn order to cure human immunodeficiency virus (HIV), we need to better understand the within-host evolutionary origins of the small reservoir of genome-intact proviruses that persist within infected cells during antiretroviral therapy (ART).
Externí odkaz:
https://doaj.org/article/1447a0402b68443b8658e7d4faad4893
Autor:
Aniqa Shahid, Bradley R Jones, Julia S W Yang, Winnie Dong, Tawimas Shaipanich, Kathryn Donohoe, Chanson J Brumme, Jeffrey B Joy, Janice M Leung, Zabrina L Brumme
Publikováno v:
PLoS Pathogens, Vol 18, Iss 11, p e1010613 (2022)
The lung is an understudied site of HIV persistence. We isolated 898 subgenomic proviral sequences (nef) by single-genome approaches from blood and lung from nine individuals on long-term suppressive antiretroviral therapy (ART), and characterized ge
Externí odkaz:
https://doaj.org/article/b8375e0e10134f47b56087abcbfb4199
Autor:
Hanwei Sudderuddin, Natalie N. Kinloch, Steven W. Jin, Rachel L. Miller, Bradley R. Jones, Chanson J. Brumme, Jeffrey B. Joy, Mark A. Brockman, Zabrina L. Brumme
Publikováno v:
Retrovirology, Vol 17, Iss 1, Pp 1-10 (2020)
Abstract The HIV accessory protein Nef downregulates the viral entry receptor CD4, the Human Leukocyte Antigen (HLA)-A and -B molecules, the Serine incorporator 5 (SERINC5) protein and other molecules from the infected cell surface, thereby promoting
Externí odkaz:
https://doaj.org/article/dd7f59c20e0e483ab4cac2ba140f1252
Autor:
F. Harrison Omondi, Hanwei Sudderuddin, Aniqa Shahid, Natalie N. Kinloch, Bradley R. Jones, Rachel L. Miller, Olivia Tsai, Daniel MacMillan, Alicja Trocha, Mark A. Brockman, Chanson J. Brumme, Jeffrey B. Joy, Richard Liang, Bruce D. Walker, Zabrina L. Brumme
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Curing HIV will require eliminating the reservoir of integrated, replication-competent proviruses that persist despite antiretroviral therapy (ART). Understanding the burden, genetic diversity, and longevity of persisting proviruses in diver
Externí odkaz:
https://doaj.org/article/e29d5e60d3034aedb7b7c5c53808e009
Autor:
Kelsie Brooks, F. Harrison Omondi, Richard H. Liang, Hanwei Sudderuddin, Bradley R. Jones, Jeffrey B. Joy, Chanson J. Brumme, Eric Hunter, Zabrina L. Brumme
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Human immunodeficiency virus (HIV) can persist as an integrated provirus, in a transcriptionally repressed state, within infected cells. This small yet enduring pool of cellular reservoirs that harbor replication-competent HIV is the main barrier to
Externí odkaz:
https://doaj.org/article/8ff485234fc84014b344a0c98b5515c5
Publikováno v:
Ecology and Evolution, Vol 9, Iss 12, Pp 6756-6771 (2019)
Abstract Cophylogeny is the congruence of phylogenetic relationships between two different groups of organisms due to their long‐term interaction. We investigated the use of tree shape distance measures to quantify the degree of cophylogeny. We imp
Externí odkaz:
https://doaj.org/article/e7245970f56d4a9d99541479d3cc083d
Autor:
Kelsie Brooks, Bradley R Jones, Dario A Dilernia, Daniel J Wilkins, Daniel T Claiborne, Samantha McInally, Jill Gilmour, William Kilembe, Jeffrey B Joy, Susan A Allen, Zabrina L Brumme, Eric Hunter
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008378 (2020)
The HIV-1 reservoir consists of latently infected cells that persist despite antiretroviral therapy (ART). Elucidating the proviral genetic composition of the reservoir, particularly in the context of pre-therapy viral diversity, is therefore importa
Externí odkaz:
https://doaj.org/article/13bf90a11ad542a4b717846ef1e5870e
Autor:
Srinath C. Yeshwant, MD, Mitchell H. Tsai, MD, MMM, Bradley R. Jones, MD, Mark P. Hamlin, MD, MS, FCCM, Ariel D. Bensimhon, MD, Daniel L. Lustgarten, MD, PhD, FHRS
Publikováno v:
HeartRhythm Case Reports, Vol 3, Iss 8, Pp 396-399 (2017)
Externí odkaz:
https://doaj.org/article/8959ab7af8fc473ea019430c7c29cebf
Autor:
Zabrina L. Brumme, Bradley R Jones, F. Harrison Omondi, Chanson J. Brumme, Natalie N. Kinloch, Olivia Tsai, Hanwei Sudderuddin, Daniel MacMillan, Mark A. Brockman, Alicja Trocha, Richard H. Liang, Bruce D. Walker, Jeffrey B. Joy, Rachel L Miller, Aniqa Shahid
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
mBio
mBio
Curing HIV will require eliminating the reservoir of integrated, replication-competent proviruses that persist despite antiretroviral therapy (ART). Understanding the burden, genetic diversity and longevity of persisting proviruses in diverse individ