Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Bradley Poteat"'
4
Data from Cell Adhesion Molecule CD166 Drives Malignant Progression and Osteolytic Disease in Multiple Myeloma
Autor: Edward F. Srour, Attaya Suvannasankha, John Chirgwin, Melissa A. Kacena, Rafat Abonour, Helmut Hanenberg, Christophe Machal, Angelo A. Cardoso, Yinghua Cheng, Bradley Poteat, Colin Crean, Hao Wu, Khalid S. Mohammad, Linlin Xu
Multiple myeloma is incurable once osteolytic lesions have seeded at skeletal sites, but factors mediating this deadly pathogenic advance remain poorly understood. Here, we report evidence of a major role for the cell adhesion molecule CD166, which w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e07796945de5b8e3296b8f4f2e2d03d
https://doi.org/10.1158/0008-5472.c.6508536.v1
Zobrazit plný text záznamu
5
Cell Adhesion Molecule CD166 Drives Malignant Progression and Osteolytic Disease in Multiple Myeloma
Autor: Attaya Suvannasankha, Christophe Machal, Helmut Hanenberg, Hao Wu, Rafat Abonour, John M. Chirgwin, Yinghua Cheng, Khalid S. Mohammad, Colin D. Crean, Edward F. Srour, Linlin Xu, Bradley Poteat, Angelo A. Cardoso, Melissa A. Kacena
Publikováno v: Cancer research. 76(23)
Multiple myeloma is incurable once osteolytic lesions have seeded at skeletal sites, but factors mediating this deadly pathogenic advance remain poorly understood. Here, we report evidence of a major role for the cell adhesion molecule CD166, which w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bdfe49b6798aaf5a7ed8764b02fb366
https://pubmed.ncbi.nlm.nih.gov/27634757
Zobrazit plný text záznamu
6
Impact of interactions of cellular components of the bone marrow microenvironment on hematopoietic stem and progenitor cell function
Autor: Brahmananda R. Chitteti, Sonia Rodriguez-Rodriguez, W. Scott Goebel, Ying Hua Cheng, Edward F. Srour, Bradley Poteat, Melissa A. Kacena, Nadia Carlesso
Publikováno v: Blood. 115:3239-3248
Hematopoietic stem (HSC) and progenitor (HPC) cell fate is governed by intrinsic and extrinsic parameters. We examined the impact of hematopoietic niche elements on HSC and HPC function by analyzing the combined effect of osteoblasts (OBs) and stroma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a96ed3ac38152506dad74ce4cff0d7
https://doi.org/10.1182/blood-2009-09-246173
Zobrazit plný text záznamu
7
CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche
Autor: Malgorzata M. Kamocka, Helmut Hanenberg, Yinghua Cheng, Amy Zollman, Hal E. Broxmeyer, Louis M. Pelus, Brahmananda R. Chitteti, Huajia Zhang, Edward F. Srour, Michihiro Kobayashi, Angelo A. Cardoso, Melissa A. Kacena, Bradley Poteat, Nadia Carlesso
Publikováno v: Blood. 124(4)
We previously showed that immature CD166(+) osteoblasts (OB) promote hematopoietic stem cell (HSC) function. Here, we demonstrate that CD166 is a functional HSC marker that identifies both murine and human long-term repopulating cells. Both murine LS
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24896eb5cfcb63d470605f7e5b33a279
https://pubmed.ncbi.nlm.nih.gov/25061166
Zobrazit plný text záznamu
8
Role Of CD166 In Multiple Myeloma Cell Homing To The Bone Marrow Microenvironment and Disease Progression
Autor: Bradley Poteat, Khalid S. Mohammad, Attaya Suvannasankha, Hao Wu, Helmut Hanenberg, Edward F. Srour, Christophe Machal, John M. Chirgwin, Linlin Xu, Colin D. Crean, Angelo A. Cardoso
Publikováno v: Blood. 122:3102-3102
Multiple myeloma (MM) is a plasma cell malignancy characterized by multiple lytic lesions throughout the skeleton, suggesting that trafficking of MM cells from the bone marrow (BM) and lodgment of these cells at secondary sites is important in diseas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45e9a263086a2ed4619ed713ce9d3e61
https://doi.org/10.1182/blood.v122.21.3102.3102
Zobrazit plný text záznamu
9
CD166 (ALCAM): A Functional Marker of Primitive Murine and Human Hematopoietic Stem Cells and Cellular Elements of Their Niche
Autor: Yinghua Cheng, Hal E. Broxmeyer, Louis M. Pelus, Brahmananda R. Chitteti, Bradley Poteat, Melissa A. Kacena, Edward F. Srour, Peirong Hu, Michihiro Kobayashi
Publikováno v: Blood. 120:640-640
Abstract 640 Phenotypic definition of murine and human hematopoietic stem cells (HSC) relies on a large number of markers. Few surface antigens with functional importance have been identified as key common markers on adult murine and human HSC. Intim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8981a7d29f4e931a3e7eb5843b0986a1
https://doi.org/10.1182/blood.v120.21.640.640
Zobrazit plný text záznamu
10
Bone Marrow Niche Attenuation by Non-Steroidal Anti-Inflammatory Drugs Mobilizes Hematopoietic Stem and Progenitor Cells by Differing Mechanisms
Autor: Bradley Poteat, Brahmananda R. Chitteti, Peirong Hu, Edward F. Srour, Khalid S. Mohammad, Jonathan Hoggatt, Pratibha Singh, Louis M. Pelus, Theresa A. Guise, Jennifer M. Speth
Publikováno v: Blood. 118:724-724
Abstract 724 Hematopoeitic stem (HSC) and progenitor cells (HPC) are localized in niches contained within the bone marrow (BM) microenvironment. To facilitate acquisition of HSC/HPC for hematopoietic transplantation, donors can be treated with granul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99ead662a21b3feac10c9494c28c5c3b
https://doi.org/10.1182/blood.v118.21.724.724
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje