Výsledky vyhledávání - "Bradley Poteat"

Supplemental figures 1-7 from Cell Adhesion Molecule CD166 Drives Malignant Progression and Osteolytic Disease in Multiple Myeloma

Autor: Edward F. Srour, Attaya Suvannasankha, John Chirgwin, Melissa A. Kacena, Rafat Abonour, Helmut Hanenberg, Christophe Machal, Angelo A. Cardoso, Yinghua Cheng, Bradley Poteat, Colin Crean, Hao Wu, Khalid S. Mohammad, Linlin Xu

S1: Distribution of CD166 mRNA expression across 30 multiple myeloma and 22 breast cancer cell lines were analyzed; S2: The percentage of CD166+ cells within H929 cells from BM-homed cells were examined flow cytometrically; S3: Data are representativ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc3465646592da6395363d113aa2399
https://doi.org/10.1158/0008-5472.22412841.v1

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Data from Cell Adhesion Molecule CD166 Drives Malignant Progression and Osteolytic Disease in Multiple Myeloma

Multiple myeloma is incurable once osteolytic lesions have seeded at skeletal sites, but factors mediating this deadly pathogenic advance remain poorly understood. Here, we report evidence of a major role for the cell adhesion molecule CD166, which w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e07796945de5b8e3296b8f4f2e2d03d
https://doi.org/10.1158/0008-5472.c.6508536.v1

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Impact of interactions of cellular components of the bone marrow microenvironment on hematopoietic stem and progenitor cell function

Autor: Brahmananda R. Chitteti, Sonia Rodriguez-Rodriguez, W. Scott Goebel, Ying Hua Cheng, Edward F. Srour, Bradley Poteat, Melissa A. Kacena, Nadia Carlesso

Publikováno v: Blood. 115:3239-3248

Hematopoietic stem (HSC) and progenitor (HPC) cell fate is governed by intrinsic and extrinsic parameters. We examined the impact of hematopoietic niche elements on HSC and HPC function by analyzing the combined effect of osteoblasts (OBs) and stroma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a96ed3ac38152506dad74ce4cff0d7
https://doi.org/10.1182/blood-2009-09-246173

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CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche

Autor: Malgorzata M. Kamocka, Helmut Hanenberg, Yinghua Cheng, Amy Zollman, Hal E. Broxmeyer, Louis M. Pelus, Brahmananda R. Chitteti, Huajia Zhang, Edward F. Srour, Michihiro Kobayashi, Angelo A. Cardoso, Melissa A. Kacena, Bradley Poteat, Nadia Carlesso

Publikováno v: Blood. 124(4)

We previously showed that immature CD166(+) osteoblasts (OB) promote hematopoietic stem cell (HSC) function. Here, we demonstrate that CD166 is a functional HSC marker that identifies both murine and human long-term repopulating cells. Both murine LS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24896eb5cfcb63d470605f7e5b33a279
https://pubmed.ncbi.nlm.nih.gov/25061166

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CD166 (ALCAM): A Functional Marker of Primitive Murine and Human Hematopoietic Stem Cells and Cellular Elements of Their Niche

Autor: Yinghua Cheng, Hal E. Broxmeyer, Louis M. Pelus, Brahmananda R. Chitteti, Bradley Poteat, Melissa A. Kacena, Edward F. Srour, Peirong Hu, Michihiro Kobayashi

Publikováno v: Blood. 120:640-640

Abstract 640 Phenotypic definition of murine and human hematopoietic stem cells (HSC) relies on a large number of markers. Few surface antigens with functional importance have been identified as key common markers on adult murine and human HSC. Intim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8981a7d29f4e931a3e7eb5843b0986a1
https://doi.org/10.1182/blood.v120.21.640.640

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Bone Marrow Niche Attenuation by Non-Steroidal Anti-Inflammatory Drugs Mobilizes Hematopoietic Stem and Progenitor Cells by Differing Mechanisms

Autor: Bradley Poteat, Brahmananda R. Chitteti, Peirong Hu, Edward F. Srour, Khalid S. Mohammad, Jonathan Hoggatt, Pratibha Singh, Louis M. Pelus, Theresa A. Guise, Jennifer M. Speth

Publikováno v: Blood. 118:724-724

Abstract 724 Hematopoeitic stem (HSC) and progenitor cells (HPC) are localized in niches contained within the bone marrow (BM) microenvironment. To facilitate acquisition of HSC/HPC for hematopoietic transplantation, donors can be treated with granul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99ead662a21b3feac10c9494c28c5c3b
https://doi.org/10.1182/blood.v118.21.724.724

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The Impact of Developmental Stage of Osteoblasts and Collagen Fibril Matrix Properties On Hematopoietic Stem Cell Function

Autor: Brahmananda R. Chitteti, Ying-Hua Cheng, Edward F. Srour, Eric Brandner, S.L. Voytik Harbin, Bradley Poteat, Melissa A. Kacena

Publikováno v: Blood. 114:3638-3638

Abstract 3638 Poster Board III-574 Previously we reported the impact of hematopoietic niche (HN) elements, calvaria-derived osteoblasts (OB) and bone marrow derived stromal cells (SC), on murine hematopoietic stem cells (HSC, defined as Lin-sca1+c-ki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fcb802ce0575946230b88c5d68b4f5d1
https://doi.org/10.1182/blood.v114.22.3638.3638

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Differential Maintenance of Cell Cycle Status of Human Bone Marrow- and Umbilical Cord Blood-Derived CD34+ Cells after Homing to the Bone Marrow Microenvironment

Autor: Karen E. Pollok, Edward F. Srour, Bradley Poteat, Attaya Suvannasankha, Brahmananda R. Chitteti

Publikováno v: Blood. 112:1327-1327

Transplanted human bone marrow (BM) CD34+ cells remain mitotically quiescent up to 72h following their homing to the BM of irradiated NOD/SCID mice (Blood2002;99(5):1585). To investigate whether umbilical cord blood (UCB)-derived CD34+ cells behave s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3e8bae5b1311d2a6c65e211b3b471dd8
https://doi.org/10.1182/blood.v112.11.1327.1327

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