Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Bradley P. Clarke"'
Autor:
Yihu Xie, Shengyan Gao, Ke Zhang, Prasanna Bhat, Bradley P. Clarke, Kimberly Batten, Menghan Mei, Matthew Gazzara, Jerry W. Shay, Kristen W. Lynch, Alexia E. Angelos, Pate S. Hill, Austin L. Ivey, Beatriz M.A. Fontoura, Yi Ren
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112988- (2023)
Summary: mRNA in eukaryotic cells is packaged into highly compacted ribonucleoprotein particles (mRNPs) in the nucleus and exported to the cytoplasm for translation. mRNP packaging and export require the evolutionarily conserved transcription-export
Externí odkaz:
https://doaj.org/article/df54e3fcb6014d21ab1a152352313d47
Publikováno v:
eLife, Vol 12 (2024)
In eukaryotes, RNAs transcribed by RNA Pol II are modified at the 5′ end with a 7-methylguanosine (m7G) cap, which is recognized by the nuclear cap binding complex (CBC). The CBC plays multiple important roles in mRNA metabolism, including transcri
Externí odkaz:
https://doaj.org/article/12579e65da634c5d8603a993028379ac
Akademický článek
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Autor:
Yun Yang, Jiwei Liu, Bradley R. Clarke, Laura Seidel, Jani R. Bolla, Philip N. Ward, Peijun Zhang, Carol V. Robinson, Chris Whitfield, James H. Naismith
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The Wzc–Wza complex forms part of the bacterial extracellular polysaccharides synthesis machinery, where cycling of the Wzc between phosphorylation states is crucial to both synthesis and export. Here the authors report the structure of the Wzc oct
Externí odkaz:
https://doaj.org/article/953375ccf8f24a0f97419d2d1888d0c0
Autor:
Leah Calvert, Mark P. Green, Geoffry N. De Iuliis, Matthew D. Dun, Brett D. Turner, Bradley O. Clarke, Andrew L. Eamens, Shaun D. Roman, Brett Nixon
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2022)
Per-fluoroalkyl and polyfluoroalkyl substances (PFAS) are a diverse group of synthetic fluorinated chemicals used widely in industry and consumer products. Due to their extensive use and chemical stability, PFAS are ubiquitous environmental contamina
Externí odkaz:
https://doaj.org/article/098e2dbc408545178278350272cfca09
Publikováno v:
eLife, Vol 10 (2021)
The evolutionarily conserved TRanscript-EXport (TREX) complex plays central roles during mRNP (messenger ribonucleoprotein) maturation and export from the nucleus to the cytoplasm. In yeast, TREX is composed of the THO sub-complex (Tho2, Hpr1, Tex1,
Externí odkaz:
https://doaj.org/article/187b40c3801e49bba4811c46bfc3123f
Autor:
Timothy L. Coggan, Damien Moodie, Adam Kolobaric, Drew Szabo, Jeff Shimeta, Nicholas D. Crosbie, Elliot Lee, Milena Fernandes, Bradley O. Clarke
Publikováno v:
Heliyon, Vol 5, Iss 8, Pp e02316- (2019)
Quantifying the emissions of per- and polyfluoroalkyl substances (PFAS) from Australian wastewater treatment plants (WWTP) is of high importance due to potential impacts on receiving aquatic ecosystems. The new Australian PFAS National Environmental
Externí odkaz:
https://doaj.org/article/58b1e54509a3444191405ede84bb82ad
Autor:
Austin L. Ivey, Pate S. Hill, Yihu Xie, Yi Ren, Bradley P. Clarke, W. Hayes McDonald, Susan R. Wente, Christopher L. Lord
Publikováno v:
Proc Natl Acad Sci U S A
The C-terminal domain (CTD) kinase I (CTDK-1) complex is the primary RNA Polymerase II (Pol II) CTD Ser2 kinase in budding yeast. CTDK-1 consists of a cyclin-dependent kinase (CDK) Ctk1, a cyclin Ctk2, and a unique subunit Ctk3 required for CTDK-1 ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424e111a3f70a253d04d7d792d2a3ba6
https://doi.org/10.1073/pnas.2019163118
https://doi.org/10.1073/pnas.2019163118
The evolutionarily conserved TREX complex plays central roles during mRNP (messenger ribonucleoprotein) maturation and export from the nucleus to the cytoplasm. In yeast, TREX is composed of the THO sub-complex (Tho2, Hpr1, Tex1, Mft1, and Thp2), the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::639919608eabc59a3200be0440cf5525
https://doi.org/10.1101/2021.01.04.425184
https://doi.org/10.1101/2021.01.04.425184
