Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Bradley M. Readnour"'
Autor:
Yetunde A. Ayinuola, Sheiny Tjia-Fleck, Bradley M. Readnour, Zhong Liang, Olawole Ayinuola, Lake N. Paul, Shaun W. Lee, Vincent A. Fischetti, Victoria A. Ploplis, Francis J. Castellino
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The proteolytic activity of human plasmin (hPm) is utilized by various cells to provide a surface protease that increases the potential of cells to migrate and disseminate. Skin-trophic Pattern D strains of Streptococcus pyogenes (GAS), e.g., GAS iso
Externí odkaz:
https://doaj.org/article/4262c9215512430a994f4458ce0b40ed
Publikováno v:
Biochemistry. 62:735-746
Cellular plasminogen (Pg) receptors (PgR) are utilized to recruit Pg, stimulate its activation to the serine protease, plasmin (Pm), and sterically protect the generated Pm from inactivation by natural host inhibitors. The net result is that cells co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0795989e1d54825f0d8a6ec809673248
https://doi.org/10.1101/2022.12.06.518574
https://doi.org/10.1101/2022.12.06.518574
Autor:
Bradley M. Readnour, Yetunde A. Ayinuola, Brady T. Russo, Zhong Liang, Vincent A. Fischetti, Victoria A. Ploplis, Shaun W. Lee, Francis J. Castellino
Human plasminogen (hPg)-binding M-protein (PAM), a major virulence factor of Pattern D Streptococcus pyogenes (GAS), is the primary receptor responsible for binding and activating hPg. PAM is covalently bound to the cell wall (CW) through cell membra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6c9037b43568ff360fe4d0b3f09dba3
https://doi.org/10.1101/2021.12.21.473763
https://doi.org/10.1101/2021.12.21.473763
Autor:
Bradley M, Readnour, Yetunde A, Ayinuola, Brady T, Russo, Zhong, Liang, Shaun W, Lee, Victoria A, Ploplis, Vincent A, Fischetti, Francis J, Castellino
Publikováno v:
Journal of Biological Chemistry. 298:101940
Trafficking of M-protein (Mprt) from the cytosol of Group A Streptococcus pyogenes (GAS) occurs via Sec translocase membrane channels that associate with Sortase A (SrtA), an enzyme that catalyzes cleavage of Mprt at the proximal C-terminal [-LPST