Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Bradley M. Minrovic"'
Autor:
Morgan E. Milton, Bradley M. Minrovic, Danni L. Harris, Brian Kang, David Jung, Caleb P. Lewis, Richele J. Thompson, Roberta J. Melander, Daina Zeng, Christian Melander, John Cavanagh
Publikováno v:
Frontiers in Molecular Biosciences, Vol 5 (2018)
2-aminoimidazole (2-AI) compounds inhibit the formation of bacterial biofilms, disperse preformed biofilms, and re-sensitize multidrug resistant bacteria to antibiotics. 2-AIs have previously been shown to interact with bacterial response regulators,
Externí odkaz:
https://doaj.org/article/082ce43dccd94bc0a0d952be55b3fb04
Autor:
Bradley M. Minrovic, Sarah E Harrill, Catherine M. Nguyen, Robert K. Ernst, Sara E. Martin, Roberta J. Melander, Colin Manoil, Christian Melander, Courtney E. Chandler, Christopher M. Brackett, Alison J. Scott
Publikováno v:
ACS Infectious Diseases. 5:1223-1230
In 2016, the World Health Organization deemed antibiotic resistance one of the biggest threats to global health, food security, and development. The need for new methods to combat infections caused by antibiotic resistant pathogens will require a var
Publikováno v:
ChemMedChem
Tuberculosis (TB) remains a significant global health problem for which new therapeutic options are sorely needed. The ability of the causative agent, Mycobacterium tuberculosis, to reside within host macrophages and form biofilm-like communities con
Autor:
Christian Melander, Roberta J. Melander, Bradley M. Minrovic, Brendan W. Corey, William M. Huggins, Daniel V. Zurawski, Anna C. Jacobs, Roger D. Sommer
Publikováno v:
ACS Medicinal Chemistry Letters. 8:27-31
With only two new classes of antibiotics developed in the last 40 years, novel antibiotics are desperately needed to combat the growing problem of multidrug-resistant and extensively drug resistant bacteria, particularly Gram-negative bacteria. Descr
Autor:
Sara E, Martin, Roberta J, Melander, Christopher M, Brackett, Alison J, Scott, Courtney E, Chandler, Catherine M, Nguyen, Bradley M, Minrovic, Sarah E, Harrill, Robert K, Ernst, Colin, Manoil, Christian, Melander
Publikováno v:
ACS Infect Dis
In 2016, the World Health Organization deemed antibiotic resistance one of the biggest threats to global health, food security, and development. The need for new methods to combat infections caused by antibiotic resistant pathogens will require a var
Autor:
Roberta J. Melander, Christian Melander, Bradley M. Minrovic, Leigh A. Jania, Veronica B Hubble, Beverly H. Koller, William T. Barker
Publikováno v:
ACS Med Chem Lett
[Image: see text] Antibiotic resistance has significantly increased since the beginning of the 21st century. Currently, the polymyxin colistin is typically viewed as the antibiotic of last resort for the treatment of multidrug resistant Gram-negative
Autor:
Roberta J. Melander, Veronica B Hubble, Christian Melander, Bradley M. Minrovic, Brittany A. Hubbard
Publikováno v:
ACS infectious diseases. 5(1)
A major contributor to fatalities in cystic fibrosis (CF) patients stems from infection with opportunistic bacterium Pseudomonas aeruginosa. As a result of the CF patient's vulnerability to bacterial infections, one of the main treatment focuses is a
Resensitizing Multidrug Resistant Bacteria to Antibiotics by Targeting Bacterial Response Regulators
Autor:
John Cavanagh, Daina Zeng, Caleb P. Lewis, Brian Kang, David Jung, Morgan E. Milton, Christian Melander, Richele J. Thompson, Danni L. Harris, G. Logan Draughn, Bradley M. Minrovic, Roberta J. Melander
Publikováno v:
The FASEB Journal. 32
Autor:
David Jung, Danni L. Harris, John Cavanagh, Richele J. Thompson, Christian Melander, Bradley M. Minrovic, Caleb P. Lewis, Morgan E. Milton, Roberta J. Melander, Daina Zeng, Brian Kang
Publikováno v:
Frontiers in Molecular Biosciences, Vol 5 (2018)
2-aminoimidazole (2-AI) compounds inhibit the formation of bacterial biofilms, disperse preformed biofilms, and re-sensitize multidrug resistant bacteria to antibiotics. 2-AIs have previously been shown to interact with bacterial response regulators,