Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bradley M. Hersh"'
Publikováno v:
Integrative and Comparative Biology
Incorporating active research opportunities into undergraduate curricula is one of the most cited elements demonstrated to improve inclusive excellence and retention in all STEM fields. Allegheny College has a long and nationally-recognized tradition
Publikováno v:
Journal of insect physiology. 98
Polydnaviruses are dsDNA viruses that induce immune and developmental alterations in their caterpillar hosts. Characterization of polydnavirus gene families and family members is necessary to understand mechanisms of pathology and evolution of these
Autor:
Sean B. Carroll, Bradley M. Hersh
Publikováno v:
Development (Cambridge, England). 132(7)
The regulation of development by Hox proteins is important in the evolution of animal morphology, but how the regulatory sequences of Hox-regulated target genes function and evolve is unclear. To understand the regulatory organization and evolution o
Publikováno v:
Genome Biology
The relationship between regulatory complexity and gene spacing was examined in Caenorhabditis elegans and Drosophila melanogaster. Intergenic distance, and hence genome architecture, is shaped by regulatory information contained in noncoding DNA.
Publikováno v:
Journal of structural biology. 137(1-2)
Invertebrates and in Drosophila, lamins and lamin-associated proteins are primary targets for cleavage by caspases. Eliminating mammalian lamins causes apoptosis, whereas expressing mutant lamins that cannot be cleaved by caspase-6 delay apoptosis. C
The misregulation of programmed cell death, or apoptosis, contributes to the pathogenesis of many diseases. We used Nomarski microscopy to screen for mutants containing refractile cell corpses in a C. elegans strain in which all programmed cell death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9927549846962da2cb32e3592b70ae8
https://europepmc.org/articles/PMC123652/
https://europepmc.org/articles/PMC123652/
Autor:
Zheng Zhou, Bradley M. Hersh, Dieter Riemer, Yosef Gruenbaum, Fangli Chen, Barbara Conradt, H. Robert Horvitz
Publikováno v:
Science
The Caenorhabditis elegans Bcl-2–like protein CED-9 prevents programmed cell death by antagonizing the Apaf-1–like cell-death activator CED-4. Endogenous CED-9 and CED-4 proteins localized to mitochondria in wild-type embryos, in which most cells
Stationary-phase cultures of Escherichia coli can survive several hours or exposure to extreme acid (pH 2 to 3), a level well below the pH range for growth (pH 4.5 to 9). To identify the genes needed for survival in extreme acid, a microliter screeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9286712e8742f19614aefc0362ab61
https://europepmc.org/articles/PMC232665/
https://europepmc.org/articles/PMC232665/
Publikováno v:
Genome Biology. 5:R25
Background Factors affecting the organization and spacing of functionally unrelated genes in metazoan genomes are not well understood. Because of the vast size of a typical metazoan genome compared to known regulatory and protein-coding regions, func
Autor:
Jamie L. Wood, Bradley M. Hersh
Publikováno v:
Developmental Biology. (1):489