Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Bradley M Zamft"'
Autor:
Thaddeus R. Cybulski, Joshua I Glaser, Adam Henry Marblestone, Bradley M Zamft, Edward S Boyden, George M Church, Konrad P Koerding
Publikováno v:
Frontiers in Computational Neuroscience, Vol 8 (2015)
To record from a given neuron, a recording technology must be able to separate the activity of that neuron from the activity of its neighbors. Here, we develop a Fisher information based framework to determine the conditions under which this is feasi
Externí odkaz:
https://doaj.org/article/ddc903d111bf47b9a2e50503f5d6571c
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131593 (2015)
Current high-resolution imaging techniques require an intact sample that preserves spatial relationships. We here present a novel approach, "puzzle imaging," that allows imaging a spatially scrambled sample. This technique takes many spatially disord
Externí odkaz:
https://doaj.org/article/ff02216ff8c744839885cacb7d412792
Autor:
Adam Henry Marblestone, Bradley M Zamft, Yael G Maguire, Mikhail G Shapiro, Thaddeus R Cybulski, Joshua I Glaser, Dario eAmodei, P. Benjamin eStranges, Reza eKalhor, David A Dalrymple, Dongjin eSeo, Elad eAlon, Michel M Maharbiz, Jose M Carmena, Jan M Rabaey, Edward S Boyden, George M Church, Konrad P Kording
Publikováno v:
Frontiers in Computational Neuroscience, Vol 7 (2013)
Simultaneously measuring the activities of all neurons in a mammalian brain at millisecond resolution is a challenge beyond the limits of existing techniques in neuroscience. Entirely new approaches may be required, motivating an analysis of the fund
Externí odkaz:
https://doaj.org/article/2d3de9c90b724ee1a1c8ae786477ce11
Autor:
Joshua I Glaser, Bradley M Zamft, Adam H Marblestone, Jeffrey R Moffitt, Keith Tyo, Edward S Boyden, George Church, Konrad P Kording
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 7, p e1003145 (2013)
A molecular device that records time-varying signals would enable new approaches in neuroscience. We have recently proposed such a device, termed a "molecular ticker tape", in which an engineered DNA polymerase (DNAP) writes time-varying signals into
Externí odkaz:
https://doaj.org/article/94b5016da9d64b199884824abbfe5445
Autor:
Jing Wu, Alexandra de Paz, Bradley M. Zamft, Adam H. Marblestone, Edward S. Boyden, Konrad P. Kording, Keith E. J. Tyo
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract DNA polymerase (pol) processivity, i.e., the bases a polymerase extends before falling off the DNA, and activity are important for copying difficult DNA sequences, including simple repeats. Y-family pols would be appealing for copying diffic
Externí odkaz:
https://doaj.org/article/f4b1ec7d932b45bca5803a0278a5f0b6
Autor:
Jamie K. Reaser, Alex Dehgan, Rebecca Aicher, Barbara T. Martinez, Bradley M. Zamft, Baisch David, Shah Selbe, Colin McCormick, Anthony J. Giordano
Publikováno v:
Biological Invasions. 22:75-100
The2016–2018National Invasive Species Council(NISC)Management Planand Executive Order 13751 call for US federal agencies to foster technology development and application to address invasive species and their impacts. This paper complements and draw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::239c9a6f6b8ef8113a436b577bcdff10
https://doi.org/10.1007/s10530-019-02146-y
https://doi.org/10.1007/s10530-019-02146-y
Autor:
Robert J. Conrado, Bradley M. Zamft
Publikováno v:
Plant Biotechnology Journal. 13:867-874
Summary Population growth and globally increasing standards of living have put a significant strain on the energy–food–water nexus. Limited water availability particularly affects agriculture, as it accounts for over 70% of global freshwater with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c947e547bd62e091cd6a80e6828aba
https://doi.org/10.1111/pbi.12382
https://doi.org/10.1111/pbi.12382
Autor:
Keith E. J. Tyo, Jing Wu, Alexandra M. De Paz, Edward S. Boyden, Adam H. Marblestone, Bradley M. Zamft, Konrad P. Kording
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
DNA polymerase (pol) processivity, i.e., the bases a polymerase extends before falling off the DNA, and activity are important for copying difficult DNA sequences, including simple repeats. Y-family pols would be appealing for copying difficult DNA a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e274db11159913c316dce1b494dea10
http://europepmc.org/articles/PMC5500549
http://europepmc.org/articles/PMC5500549
Publikováno v:
Proceedings of the National Academy of Sciences. 109:8948-8953
RNA polymerase pausing represents an important mechanism of transcriptional regulation. In this study, we use a single-molecule transcription assay to investigate the effect of template base-pair composition on pausing by RNA polymerase II and the ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7729f25ac0974ea4cff5a14bc704d4d5
https://doi.org/10.1073/pnas.1205063109
https://doi.org/10.1073/pnas.1205063109
Autor:
Keith E. J. Tyo, Edward S. Boyden, Thaddeus R Cybulski, George M. Church, Adam H. Marblestone, Konrad P. Kording, Bradley M. Zamft, Alexandra M. De Paz
Publikováno v:
Nucleic Acids Research
DNA polymerase fidelity is affected by both intrinsic properties and environmental conditions. Current strategies for measuring DNA polymerase error rate in vitro are constrained by low error subtype sensitivity, poor scalability, and lack of flexibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf89c61650e3f8be3adfcb63bfd515e
https://doi.org/10.1093/nar/gky296
https://doi.org/10.1093/nar/gky296