Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Bradley M Wertheim"'
Autor:
Bradley M Wertheim, Yi-Dong Lin, Ying-Yi Zhang, Andriy O Samokhin, George A Alba, Elena Arons, Paul B Yu, Bradley A Maron
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0211909 (2019)
Transcriptomic analysis of pulmonary microvascular endothelial cells from experimental models offers insight into pulmonary arterial hypertension (PAH) pathobiology. However, culturing may alter the molecular profile of endothelial cells prior to ana
Externí odkaz:
https://doaj.org/article/4a71bc43facd414a8f4b147aaf23b9d9
Iatrogenic esophageal dysmotility as a barrier to transplantation in pulmonary arterial hypertension
Autor:
Michael S. Miller, Shelsey W. Johnson, Alexander R. Opotowsky, Michael J. Landzberg, Nirmal S. Sharma, Hilary J. Goldberg, Alexandra K. Wong, Alison S. Witkin, Josanna Rodriguez-Lopez, Ronald H. Goldstein, Bradley A. Maron, Bradley M. Wertheim
Publikováno v:
JHLT Open, Vol 5, Iss , Pp 100098- (2024)
Esophageal dysmotility is identified as a contraindication to lung transplantation at some centers due to increased risks of acute rejection, pulmonary infection, and chronic lung allograft dysfunction. Phosphodiesterase-type 5 inhibitors (PDE5i) are
Externí odkaz:
https://doaj.org/article/4145d27170eb4e76b982c3e6fb360f36
Autor:
Bradley M. Wertheim, Rui-Sheng Wang, Christelle Guillermier, Christiane V.R. Hütter, William M. Oldham, Jörg Menche, Matthew L. Steinhauser, Bradley A. Maron
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
In pulmonary arterial hypertension (PAH), inflammation promotes a fibroproliferative pulmonary vasculopathy. Reductionist studies emphasizing single biochemical reactions suggest a shift toward glycolytic metabolism in PAH; however, key questions rem
Externí odkaz:
https://doaj.org/article/3241f24b97504570a5420e07c730d523
Publikováno v:
J Voice
Summary Introduction Inducible laryngeal obstruction is a common and challenging cause of exertional dyspnea. We report a case of an unanticipated cardiac condition that presented with symptoms suggestive of inducible laryngeal obstruction. Discussio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8541ff67bd28fbf047a0a29cab731f49
https://doi.org/10.1016/j.jvoice.2020.12.002
https://doi.org/10.1016/j.jvoice.2020.12.002
Autor:
Shaan Khurshid, Timothy W. Churchill, Nathaniel Diamant, Paolo Di Achille, Christopher Reeder, Pulkit Singh, Meagan Wasfy, George A. Alba, Bradley A. Maron, David M. Systrom, Bradley M. Wertheim, null Patrick
Publikováno v:
Journal of Electrocardiology. 78:31-32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d788f3083be5aa61a2fb9b218b56c861
https://doi.org/10.1016/j.jelectrocard.2023.03.068
https://doi.org/10.1016/j.jelectrocard.2023.03.068
Autor:
Bradley A. Maron, David E. Kleiner, Elena Arons, Bradley M. Wertheim, Nirmal S. Sharma, Kathleen J. Haley, Andriy O. Samokhin, Ethan J. Rowin, Martin S. Maron, Douglas R. Rosing, Barry J. Maron
Publikováno v:
Chest.
Elevated mean pulmonary artery pressure (mPAP) is common in patients with hypertrophic cardiomyopathy (HCM) and heart failure symptoms. However, dynamic left ventricular (LV) outflow tract obstruction may confound interpretation of pulmonary hyperten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be21ac235de495c5d0d96bb3c0e534f7
https://pubmed.ncbi.nlm.nih.gov/36243062
https://pubmed.ncbi.nlm.nih.gov/36243062
Autor:
George A. Alba, Andriy O. Samokhin, Rui‐Sheng Wang, Bradley M. Wertheim, Kathleen J. Haley, Robert F. Padera, Sara O. Vargas, Ivan O. Rosas, Lida P. Hariri, Angela Shih, Boyd Taylor Thompson, Richard N. Mitchell, Bradley A. Maron
Publikováno v:
Pulmonary Circulation. 12
The pathobiology of in situ pulmonary thrombosis in acute respiratory distress syndrome (ARDS) due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is incompletely characterized. In human pulmonary artery endothelial cells (H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55dc2593c888421438c530579811800
https://doi.org/10.1002/pul2.12071
https://doi.org/10.1002/pul2.12071
Autor:
Corey E. Ventetuolo, Bradley M. Wertheim, Mariana Faria-Urbina, Frederick P. Bowman, Peter J. Leary, Richard N. Channick, Ryan J. Tedford, George A. Alba, Bradley A. Maron, Aaron B. Waxman, C. Danielle Hopkins, Andriy O. Samokhin, Jane A. Leopold, Ivana Nikolic, Paul B. Yu, Steven Hsu, Paul M. Hassoun
Publikováno v:
The Journal of Heart and Lung Transplantation. 39:289-299
Pulmonary arterial hypertension (PAH) is a highly morbid disease characterized by elevated pulmonary vascular resistance (PVR) and pathogenic right ventricular remodeling. Endothelial expression of the prometastatic protein NEDD9 is increased in fibr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46d9980685d4a5d498ff033a8d339d0
https://doi.org/10.1016/j.healun.2019.12.002
https://doi.org/10.1016/j.healun.2019.12.002
Publikováno v:
Circulation. 144
Introduction: Pulmonary vascular endothelial cell injury, dysfunction, and apoptosis are associated with the development of pulmonary arterial hypertension (PAH). Improving endothelial function may be therapeutically beneficial in this disorder. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3366ceeba622e70ba087b28930d4d4e6
https://doi.org/10.1161/circ.144.suppl_1.11090
https://doi.org/10.1161/circ.144.suppl_1.11090
Autor:
Bradley M Wertheim, Rui-Sheng Wang, Yingyi Zhang, Andriy O Samokhin, George A Alba, Elena Arons, William M Oldham, Bradley A Maron
Publikováno v:
Circulation. 144
Introduction: Advanced-stage pulmonary arterial hypertension (asPAH) is characterized by endothelial dysfunction and fibrotic remodeling of pulmonary arterioles that promotes irreversible right heart failure. Thus, identifying mechanisms that regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39c80f008bbaadf4fde59276f6899307
https://doi.org/10.1161/circ.144.suppl_1.10815
https://doi.org/10.1161/circ.144.suppl_1.10815