Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bradley Lockwood"'
Autor:
Macdonald Lynn, Kara Anasti, Barton F. Haynes, Ryan Duffy, S. Munir Alam, M. Anthony Moody, Christos A. Kyratsous, Andrew J. Murphy, Krissey E. Lloyd, Cindy M. Bowman, Shi-Mao Xia, Nathan I. Nicely, Richard M. Scearce, Robert Parks, Masayuki Kuraoka, Christina Stolarchuk, Laurent Verkoczy, Garnett Kelsoe, Kevin Wiehe, Xiaoying Shen, Bradley Lockwood, Georgia D. Tomaras, Sabrina Arora
Publikováno v:
The Journal of Immunology. 198:1047-1055
In the RV144 gp120 HIV vaccine trial, decreased transmission risk was correlated with Abs that reacted with a linear epitope at a lysine residue at position 169 (K169) in the HIV-1 envelope (Env) V2 region. The K169 V2 response was restricted to Abs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48824f0452c21bb8456dc29fcdfb9927
https://doi.org/10.4049/jimmunol.1601640
https://doi.org/10.4049/jimmunol.1601640
Autor:
S. Moses Dennison, Hua-Xin Liao, Richard M. Scearce, Barton F. Haynes, Yao Chen, Laurent Verkoczy, Shi-Mao Xia, Amanda Newman, Bradley Lockwood, Hilary Bouton-Verville, Kwan-Ki Hwang, David C. Montefiori, S. Munir Alam, Jinsong Zhang
Publikováno v:
The Journal of Immunology. 191:2538-2550
A goal of HIV-1 vaccine development is to elicit broadly neutralizing Abs (BnAbs). Using a knock-in (KI) model of 2F5, a human HIV-1 gp41 membrane proximal external region (MPER)–specific BnAb, we previously demonstrated that a key obstacle to BnAb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7bf02a2670291c8af3d09537236bea
https://doi.org/10.4049/jimmunol.1300971
https://doi.org/10.4049/jimmunol.1300971
Autor:
Per Brandtzaeg, Kwan-Ki Hwang, Robert Parks, Jae-Sung Yu, S. Munir Alam, Hua-Xin Liao, Ruijun Zhang, Richard M. Scearce, Sallie R. Permar, Bradley Lockwood, Barton F. Haynes
Immunoglobulin A (IgA) antibodies exist in monomeric, dimeric, and secretory forms. Dimerization of IgA depends on a 15-kD polypeptide termed "joining (J) chain," which is also part of the binding site for an epithelial glycoprotein called "secretory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394813bdc92631b7d9473c3dace3d57c
https://europepmc.org/articles/PMC5003010/
https://europepmc.org/articles/PMC5003010/
Autor:
Bronwen E. Lambson, Hua-Xin Liao, Barton F. Haynes, Frederick H. Jaeger, Thomas B. Kepler, Georgia D. Tomaras, Ashley M. Trama, Katherine J. L. Jackson, M. Anthony Moody, Richard M. Scearce, Krishna M. Roskin, John F. Whitesides, Kelly A. Soderberg, Kwan-Ki Hwang, Andrew Foulger, Bradley Lockwood, Robert Parks, Krissey E. Lloyd, Thomas Lee Jeffries, Lynn Morris, Christina Stolarchuk, Kevin Wiehe, Dawn J. Marshall, Scott D. Boyd, Nathan Vandergrift, S. Munir Alam
Publikováno v:
Cell hostmicrobe. 16(2)
SummaryMonoclonal antibodies derived from blood plasma cells of acute HIV-1-infected individuals are predominantly targeted to the HIV Env gp41 and cross-reactive with commensal bacteria. To understand this phenomenon, we examined anti-HIV responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9daf72131426743a9f7aea704418bd8
https://pubmed.ncbi.nlm.nih.gov/25121750
https://pubmed.ncbi.nlm.nih.gov/25121750