Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Bradley Lega"'
Autor:
Daniel Peterson, Mark Van Poppel, Warren Boling, Perry Santos, Jason Schwalb, Howard Eisenberg, Ashesh Mehta, Heather Spader, James Botros, Frank D. Vrionis, Andrew Ko, P. David Adelson, Bradley Lega, Peter Konrad, Guillermo Calle, Fernando L. Vale, Richard Bucholz, R. Mark Richardson
Publikováno v:
Bioelectronic Medicine, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Background Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that causes persistent synovitis, bone damage, and progressive joint destruction. Neuroimmune modulation through electrical stimulation of the vagus nerve acti
Externí odkaz:
https://doaj.org/article/232b307d56d140b89ba5f4167a82f3ee
Autor:
Tamara Gedankien, Ryan Joseph Tan, Salman Ehtesham Qasim, Haley Moore, David McDonagh, Joshua Jacobs, Bradley Lega
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The cholinergic system is essential for memory. While degradation of cholinergic pathways characterizes memory-related disorders such as Alzheimer’s disease, the neurophysiological mechanisms linking the cholinergic system to human memory
Externí odkaz:
https://doaj.org/article/ab383e5b96ee4c28941ec6a5a2ff8ee2
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Neuronal assemblies remain understudied in human data. Here, the authors show that gamma phase-locked neuronal firing sequences comprise assemblies in human single unit recordings, and their ability to incorporate new neurons over time facilitates me
Externí odkaz:
https://doaj.org/article/05a131cfc177400591ed8664770ec3fb
Publikováno v:
Current Research in Neurobiology, Vol 5, Iss , Pp 100109- (2023)
The role of thalamocortical circuits in memory has driven a recent burst of scholarship, especially in animal models. Investigating this circuitry in humans is more challenging. And yet, the development of new recording and stimulation technologies d
Externí odkaz:
https://doaj.org/article/923d80380cf14f53a326a0406ed1492e
Publikováno v:
NeuroImage, Vol 257, Iss , Pp 119281- (2022)
Externí odkaz:
https://doaj.org/article/f0ff9631251543459de0fa77372d9f33
Autor:
Abhinav Goyal, Jonathan Miller, Salman E. Qasim, Andrew J. Watrous, Honghui Zhang, Joel M. Stein, Cory S. Inman, Robert E. Gross, Jon T. Willie, Bradley Lega, Jui-Jui Lin, Ashwini Sharan, Chengyuan Wu, Michael R. Sperling, Sameer A. Sheth, Guy M. McKhann, Elliot H. Smith, Catherine Schevon, Joshua Jacobs
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
We show that the human hippocampus exhibits two distinct theta oscillations during spatial navigation with the faster oscillation in posterior regions showing movement modulation. This result suggests a distinct feature of the human hippocampus compa
Externí odkaz:
https://doaj.org/article/467989c30c504da28bda4332b96d7324
Publikováno v:
Epilepsy & Behavior Reports, Vol 20, Iss , Pp 100569- (2022)
Objective: The object of this case series is to report the effectiveness and complication rates of presurgical evaluation and surgical treatment among elderly epilepsy patients in our clinic. Methods: We reviewed patients charts from 2016 to 2020 and
Externí odkaz:
https://doaj.org/article/5e531b9174e4467eaf7694c4599d1262
Publikováno v:
NeuroImage, Vol 245, Iss , Pp 118689- (2021)
Episodic memory requires associating items with temporal context, a process for which the medial temporal lobe (MTL) is critical. This study uses recordings from 27 human subjects who were undergoing surgical intervention for intractable epilepsy. Th
Externí odkaz:
https://doaj.org/article/9e6ab531548d49b6b6502130db06eb9f
Autor:
Ghazala Perven, Irina Podkorytova, Kan Ding, Mark Agostini, Sasha Alick, Rohit Das, Hina Dave, Marisara Dieppa, Alexander Doyle, Jay Harvey, Bradley Lega, Rodrigo Zepeda, Ryan Hays
Publikováno v:
Epilepsy & Behavior Reports, Vol 15, Iss , Pp 100441- (2021)
Purpose: Mesial temporal lobe epilepsy (MTLE) usually responds well to surgical treatment, although in non-lesional cases up to 50% of patients experience seizure relapse. The possibility of bilateral independent seizure onset should be considered as
Externí odkaz:
https://doaj.org/article/71c6102ab9d14953b836be878d12ef53
Autor:
Jonathan Miller, Andrew J. Watrous, Melina Tsitsiklis, Sang Ah Lee, Sameer A. Sheth, Catherine A. Schevon, Elliot H. Smith, Michael R. Sperling, Ashwini Sharan, Ali Akbar Asadi-Pooya, Gregory A. Worrell, Stephen Meisenhelter, Cory S. Inman, Kathryn A. Davis, Bradley Lega, Paul A. Wanda, Sandhitsu R. Das, Joel M. Stein, Richard Gorniak, Joshua Jacobs
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Theta oscillations are implicated in memory formation. Here, the authors show that low-theta oscillations in the hippocampus are differentially modulated between each hemisphere, with oscillations in the left increasing when successfully learning obj
Externí odkaz:
https://doaj.org/article/f92b2df7e7ee4c03a6f3725832bc4595