Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Bradley John Hedberg"'
Autor:
Zemane W'Giorgis, Bradley John Hedberg, Audrey Weber, Sergey Vshyvenko, Tomas Hudlicky, Natalia Neverova
Publikováno v:
Advanced Synthesis & Catalysis. 357:83-87
The first active aza analogue of narciclasine was synthesized from a pentasubstituted derivative of nicotinic acid. The key features of the synthesis include a halogen dance of bromopyridine and an intramolecular Heck reaction with a conduramine deri
Autor:
Janine LoBello, Yang Mao, Glen J. Weiss, Robert Dagil, Jeff Trent, Jo Soden, Ladan Fazli, Jim Freeth, Bradley John Hedberg, Chris K. Wang, Sherry Lee, Adam F. Sander, John Babcook, Makoto Endo, Francesco Favero, Jamie R. Rich, Peter Johannes Holst, Joseph Zaia, Morten Nielsen, Madeleine Dahlbäck, Poul H. Sorensen, Nhan L. Tran, Marina Ayres Pereira, Tobias Gustavsson, Line Barington, Torsten O. Nielsen, Thomas Mandel Clausen, Ali Salanti, Htoo Zarni Oo, Le Meng, Mette Ø. Agerbæk, Nader Al Nakouzi, Mads Daugaard, Thor G. Theander, Susan Thrane
Publikováno v:
Cancer cell. 28(4)
SummaryPlasmodium falciparum engineer infected erythrocytes to present the malarial protein, VAR2CSA, which binds a distinct type chondroitin sulfate (CS) exclusively expressed in the placenta. Here, we show that the same CS modification is present o
Autor:
Bradley John Hedberg, Sergey Vshyvenko, Audrey Weber, Natalia Neverova, Tomas Hudlicky, Zemane W'Giorgis
Publikováno v:
ChemInform. 46
Title compound (VI) is synthesized starting from pyridine derivative (I) over 12 steps in an overall yield of 2.05%.
Autor:
Peter Bergqvist, John A. Wilkins, Julie S. Nielsen, Michael R. Hughes, Diana Canals Hernaez, Kimberly Snyder, Michelle E Turvey, Bradley John Hedberg, Kelvin Po, Calvin D. Roskelley, Frederic Cruz, Jill Brandon, Shaun R. McColl, Kelly M. McNagny, Marcia L. Graves, John Babcook
Publikováno v:
Breast Cancer Research : BCR
Introduction Podocalyxin (gene name PODXL) is a CD34-related sialomucin implicated in the regulation of cell adhesion, migration and polarity. Upregulated expression of podocalyxin is linked to poor patient survival in epithelial cancers. However, it
Autor:
Bradley John Hedberg, Richard D. Swayze, Daryanaz Dargahi, Peter Bergqvist, Christopher J. Bond, Alireza Heravi-Moussavi, John Babcook, Jianghong An, Ryan Dercho, Leanna Yee, Steven J.M. Jones, Edie Dullaghan
Publikováno v:
Cancer Research. 75:2187-2187
Cancer is fundamentally a disease of disordered gene expression. In fact, reversal or neutralization of the changes in gene expression has been shown to be attractive targets for the development of new anti-cancer drugs and therapeutic strategies. Ne